USE OF ANIMATION IN TEACHING PHYSIOLOGY

Objectives: To evaluate the gain in knowledge of first year MBBS students with the use of animation. Methodology: Prospective Interventional study was conducted in department of physiology. 200 first year MBBS students participated in the study. 100 students (Group-A) were taken as control group to them the topic of physiology was taught by didactic method and another 100 students (Group-B) were taken as intervention group, where the same topic was taught with Power point presentation along with animation. For each lecture preand posttest was taken. Five consecutive lectures were planned with this intervention. At the same time feedback forms were given to intervention group for purpose of analyzing the results qualitatively. After this intervention the crossover of groups were done only for the sake of getting benefit of intervention. Results: Data obtained was analyzed statistically. Pre and posttest mean were taken. Key words: Animation; Chalk and board; Overhead projector; Teaching aids; Visual impact

USE OF ANIMATION IN TEACHING PHYSIOLOGY

Objectives: To evaluate the gain in knowledge of first year MBBS students with the use of animation. Methodology: Prospective Interventional study was conducted in department of physiology. 200 first year MBBS students participated in the study. 100 students (Group-A) were taken as control group to them the topic of physiology was taught by didactic method and another 100 students (Group-B) were taken as intervention group, where the same topic was taught with Power point presentation along with animation. For each lecture preand posttest was taken. Five consecutive lectures were planned with this intervention. At the same time feedback forms were given to intervention group for purpose of analyzing the results qualitatively. After this intervention the crossover of groups were done only for the sake of getting benefit of intervention. Results: Data obtained was analyzed statistically. Pre and posttest mean were taken. Key words: Animation; Chalk and board; Overhead projector; Teaching aids; Visual impact

Screening study of dipstick urinalysis of healthy neonates delivered in tertiary care hospital, from Vadodara, Gujarat

Background: Urinary dipstick is one of the most important advances in the current diagnostic procedure in pediatric nephrourology. Dipstick test is easy to perform bedside test, gives an immediate result, is relatively cheap, and require less sophisticated training of personnel; so could be used for asymptomatic patients. Objectives: The objectives of the study were to evaluate the usefulness of urine dipstick bedside screening test for diagnosis of underlying congenital kidney disease in otherwise healthy neonates. Materials and Methods: The study was conducted from April 2018 to November 2018. A total of 900 healthy newborns were enrolled. Random spot urine samples were obtained within first 72 h of life. Dipstick test was performed using Siemens Multistix 10SG and positive or negative reading for biochemical parameters was recorded and compared with laboratory test. Newborns with 1st positive dipstick test were issued screen positive cards and called for follow-up on 7th day of life for 2nd dipstick test. Those with persistent 2nd dipstick positive were further investigated to rule out any congenital anomaly. Results: Of total 900 neonates, 504 (56%) were males and 396 (44%) were females. Of the total newborns, 441 (49%) were positive for proteinuria, 2 (0.2%) for nitrites, and 54 (6%) for leukocytes during 1st dipstick urinalysis. Urine routine microscopic evaluation showed 450 (50%) positive for protein and 322 (35%) positive for pus cells. On subsequent follow-up of positive cases, only 2 (0.5%) newborns were positive for proteinuria on 2nd dipstick (p=0.7061). Conclusion: Bedside dipstick urine test as a screening test was not useful in otherwise healthy neonates due to renal immaturity in first few days of life

To Study the Siddhant “Saman Gunabhyaso Hi Dhatunam Vriddhikaranam Iti” with respect to Shukrakshaya (Oligospermia) by using Vrishya Shatavari Ghrit

Ayurveda is oldest tradition addressing major healthcare issues in sophispticated way. There are number of modern medicines giving relief to the patients but having adverse effects at highest level. Ayurveda smartly not only addresses the issues but having less side effects. Current study focuses the use of Shatavarighrit in shukrakshay (oligospermia) patients. The study comes to a conclusion with a promising results in the patients of oligospermia. The study result to reduce the burden for patients and giving light who having infertility

Formulation and Evaluation of Floating In-Situ Gel of Nicardipine Hydrochloride

The present research work aimed to formulate and evaluate a gastro retentive in situ gelling system of Nicardipine Hydrochloride using Sodium Alginate as gelling polymer, HPMC K100M as release retard polymer, calcium carbonate as a cross-linking agent, and tri-sodium citrate as fluidity enhancer agent to treat hypertension. The mechanism for the floatation was based on ionic cross-linking. Several evaluation tests were carried out for pre and final formulation evaluation. Based on the outcomes white-colored, viscous solution of uniform consistency was obtained. Batch B1 was very well prepared for the ability to control long-term drug release. The drug content was found to be > 97 %, the viscosities were in the acceptable range suitable for swallowing, and pH was found to be in the range of 7.33 – 7.68 which was compatible with oral digestion. Design expert 13 Software was used to derive results of interaction and responses based on the concentration of polymer and statistical analysis. The optimized formulation i.e., Batch B1 (0.6 % w/v and 0.5 % w/v HPMC K100M) showed a slow drug release of 96.44 % up to 12 hours. The best fit model for the drug release followed the Higuchi model which explained that the drug release occurred by the Fiskian mechanism i.e., a combination of both diffusion and erosion. The in-situ gel prepared can ultimately provide prolonged release, enhance the bioavailability of the drug and increase patient compliance. Keywords: - In situ gel, Ionic cross linking, Sodium alginate, HPMC K100M, Nicardipine Hydrochloride

Corona virus crisis: Ground reality during the lockdown

The Corona virus pandemic has caused devastating effects across the world. With loss of tens and millions of lives and economic shutdown, the pandemic has caused a catastrophic effect which is to be felt by generations to come. This piece reflects on the social, emotional and economical consequences of the ongoing crisis as well as the extreme lockdown that has had overwhelming effect on millions of people across the globe. The Covid 19 pandemic has claimed many lives around the world and poses an unparalleled danger to public health, the food supply, and the workplace. During the lockdown, mental health problems and suicides are at an all-time high. Mental health conditions such as depression, anxiety, and stress are common during the lockdown.Women and infants, who are the most disadvantaged members of society, are more vulnerable to mental health problems and domestic abuse

Moths (Insecta: Lepidoptera) of Delhi, India: An illustrated checklist based on museum specimens and surveys

There have been several recent checklists, books and publications about Indian moths; however, much of this work has focused on biodiversity hotspots such as North-east India, Western Ghats and Western Himalayas. There is a lack of published literature on urban centres in India, despite the increased need to monitor insects at sites with high levels of human disturbance. In this study, we examine the moths of Delhi, the national capital region of India, one of the fastest growing mega-metropolitan cities. We present a comprehensive checklist of 338 moths species using 8 years of light trapping data (2012-2020) and examining about 2000 specimens from historical collections at the National Pusa Collection of ICAR-Indian Agricultural Research Institute, New Delhi (NPC-IARI) spanning over 100 years (1907-2020). The checklist comprises moths from 32 families spanning 14 superfamilies with Noctuoidea (48.5%) and Pyraloidea (20.4%) being the the two most dominant superfamilies. We provide links to images of live individuals and pinned specimens for all moths and provide detailed distribution records and an updated taxonomic treatment.This is the first comprehensive annotated checklist of the moths of Delhi. The present study adds 234 species to the biodiversity of moths from Delhi that were not reported previously, along with illustrations for 195 species

To fabricate and evaluate the wound healing activity of herbal medicated plasters containing the extracts obtained from Tridax procumbens and Azadirachta indica

The present research work is to fabricate medicated plaster containing herbal extracts for wound healing properties. Till date no herbal medicated plaster have been prepared and evaluated using the extracts obtained from the plants Neem and Coatbutton. The objective of the present studyis to provide the herbal medicated plasters to the society. The majoradvantage of this medicated herbal plaster is its safety, efficacy, portability and efficiency. There is much more study such as Collection of plant, Extraction of plant materials and their antimicrobial test, Evaluation of qualitative and quantitative test, Estimation of total phenolic content, Antioxidant study, Antimicrobial study, Estimation of patch test, Antimicrobial studies of patch test. The plant extracts were quantitatively analysed for total flavonoids content, total phenolic content, and antioxidant activity. Methanolic extract of Azadirechta indica and Tridax procumbens has shown presence of high content of flavonoids and total phenolic content. Also the Azadirachtin content in the neem extracts was determined. All the six extracts AIME, AIPE, AIAE, TPME, TPPE and TPAE were subjected to antimicrobial activity.In patch test FII batch shows the excellent antimicrobial activity.FII patch was selected for fabrication of plasters which was then subjected to the pharmacological study