Detection of Drug Interactions via Android Smartphone: Design and Implementation

Despite the morbidity and cases of widespread drug poisoning, clinical guidelines are largely written by taking into account only one treatment at a time. The cumulative impact of multiple treatments is rarely considered. Drug treatment for people with several diseases produces a complex regimen called “polypharmacy” with a potential combination of harmful and even lethal drugs that can be prevented. This polypharmacy causes in many cases the death of some people due to drug interactions. The vast majority of these deaths can be prevented by detecting interactions before taking these medications. But the problem is that such information exists in a state that is difficult to access for the general public, much less for people with little knowledge in the field. Although the pharmacist is unmistakable and most viable source to avoid such a problem, he cannot know what the patient does not mention because he is not aware of what may affect his treatment. To remedy this, we aim in this paper to develop an ergonomic Android application that will inform the patient about the potential risks of such drug interactions. The application is optimized to handle various databases and operate automation of QR code

Dynamics of the Amplitude-to-Phase Coupling of 1.5µm High Bandwidth Commercial Photodiodes

National audienceWe investigate the power-to-phase coupling in two commercial high bandwidth P-i-N near-IR photodetectors. We observe that a sudden change of the optical power induces a transient of the phase of the 20 GHz signal, at different time scales. The temperature rise of the photodetector junction is likely to be involved in this dynamical behaviour. The value of the bias voltage applied to the photodetector appears to control the size of the phase transients, as well as the optical power for which the slope of the amplitude-to-phase coupling cancels. These results are important in optimising RF optical links

Phase measurement of a microwave optical modulation: characterisation and reduction of amplitude-to-phase conversion in 1.5 µm high bandwidth photodiodes

En attente de publication papier; Lien vers l'éditeur: http://ieeexplore.ieee.org/xpl/articleDetails.jsp? arnumber=6775285&sortType%3Dasc_p_Sequence% 26filter%3DAND%28p_IS_Number%3A4357488%29International audienceHigh accuracy and low noise measurement of the phase of a microwave signal requires that spurious contributions are adequately dealt with. In this paper we investigate the power-to-phase coupling in two commercial high bandwidth P-I-N, near-IR photodetectors. We observe that a sudden change of the optical power induces a transient of the phase of the 20 GHz signal, at different time scales. The temperature rise of the photodetector junction is likely to be involved in this dynamical behaviour. The value of the bias voltage applied to the photodetector appears to control the size of the phase transients, as well as the optical power for which the slope of the amplitude-to-phase coupling cancels. The most efficient way to reduce amplitude to phase couplings consists in implementing optical demodulation, instead of electrical demodulation, of the microwave signal

Couplage amplitude-phase dans les photodiodes à grande bande passante: caractérisation statique et dynamique de photodiodes PIN InGaAs à 20GHz; transitoires d'échauffement de la jonction

International audienceLes photodiodes rapides sont un composant crucial des dispositifs opto-microondes. Les défauts desphotodiodes (non-linéarités, diaphonies, couplages amplitude-phase, ?) interviennent à des degrésdivers dans les utilisations qui en sont faites pour transformer en un photocourant les informationstransportées par le faisceau. Le couplage AM-PM est une contrainte dans les liens optiques: la limitesur le bruit de phase se traduit en une limite sur le bruit de puissance du faisceau sur lequel est codéle signal. Lorsque le bruit de phase à atteindre est très faible et conduit à des contraintes irréalistessur le bruit de puissance, une solution est de rechercher les conditions qui permettent de diminuer lavaleur du coefficient de couplage amplitude-phase

Caractérisation de l'amplificateur du système laser pré-stabilisé pour advanced Virgo

National audienceAdvanced Virgo est la version de seconde génération du détecteur d'ondes gravitationnelles Virgo. Sa sensibilité est accrue d'un facteur 10, grâce notamment à l'augmentation de la puissance optique. Un amplificateur 95 W a été étudié et caractérisé. Ses performances mesurées son compatibles avec les exigences du nouveau système laser pré-stabilisé

High bandwidth frequency lock of a rigid tunable optical cavity

International audienceIn this paper, we present a high bandwidth frequency lock of a rigid tunable Fabry Perot cavity based on a set of lead zirconate titanate (PZT) actuators. The cavity spacer was specifically designed such that the frequency of the first resonance of the whole assembly under PZT excitation is above 35 kHz, thus allowing a servo-loop bandwidth of 13 kHz. It is demonstrated that no significant noise is added by the cavity to the output beam with respect to the input beam over the servo-loop bandwidth. This cavity can be used as a pre-mode cleaner in interferometric gravitational wave detectors such as the Laser Interferometer Gravitational-Wave Observatory (LIGO) and Virgo

Laser power stabilization for Advanced VIRGO

International audienceSecond generation of laser interferometer gravitational wave detectors can now detect the fusion of compact stellar object pair weekly. To increase the sensitivity, an important change of design between first and second generation gravitational wave detectors is the use of homodyne detection instead of heterodyne. This modification has strongly increased the requirement on laser power stabilization for Advanced VIRGO [1] . The relative intensity noise (RIN) requirement depends on the effective defects of the interferometer mirrors and its operational state. It spans between 10 -8 Hz -1/2 and 1.2×10 -9 Hz -1/2 at 30 Hz for the most sensitive future configuration (2024)

Design et caractérisation des photorécepteurs à quadrants pour l’AIVT de l’instrument spatial LISA

National audienceCette contribution présente la conception, la réalisation et les mesures de performance des photorécepteurs à quadrants dédiés aux activités d’Assemblage, d’Intégration, de Validation et de Tests (AIVT) de l’instrument Laser Interferometer Space Antenna (LISA), futur détecteur spatial d’ondes gravitationnelles

Design et caractérisation des photorécepteurs à quadrants pour l’AIVT de l’instrument spatial LISA

National audienceCette contribution présente la conception, la réalisation et les mesures de performance des photorécepteurs à quadrants dédiés aux activités d’Assemblage, d’Intégration, de Validation et de Tests (AIVT) de l’instrument Laser Interferometer Space Antenna (LISA), futur détecteur spatial d’ondes gravitationnelles

Matter-wave laser Interferometric Gravitation Antenna (MIGA): New perspectives for fundamental physics and geosciences

International audienceThe MIGA project aims at demonstrating precision measurements of gravity with cold atom sensors in a large scale instrument and at studying the associated applications in geosciences and fundamental physics. The first stage of the project (2013-2018) will consist in building a 300-meter long optical cavity to interrogate atom interferometers and will be based at the low noise underground laboratory LSBB in Rustrel, France. The second stage of the project (2018-2023) will be dedicated to science runs and data analyses in order to probe the spatio-temporal structure of the local gravity field of the LSBB region, a site of high hydrological interest. MIGA will also assess future potential applications of atom interferometry to gravitational wave detection in the frequency band ∼0.1−10 Hz hardly covered by future long baseline optical interferometers. This paper presents the main objectives of the project, the status of the construction of the instrument and the motivation for the applications of MIGA in geosciences. Important results on new atom interferometry techniques developed at SYRTE in the context of MIGA and paving the way to precision gravity measurements are also reported