Compact parity conserving percolation in one-dimension

Compact directed percolation is known to appear at the endpoint of the directed percolation critical line of the Domany-Kinzel cellular automaton in 1+1 dimension. Equivalently, such transition occurs at zero temperature in a magnetic field H, upon changing the sign of H, in the one-dimensional Glauber-Ising model with well known exponents characterising spin-cluster growth. We have investigated here numerically these exponents in the non-equilibrium generalization (NEKIM) of the Glauber model in the vicinity of the parity-conserving phase transition point of the kinks. Critical fluctuations on the level of kinks are found to affect drastically the characteristic exponents of spreading of spins while the hyperscaling relation holds in its form appropriate for compact clusters.Comment: 7 pages, 7 figures embedded in the latex, final form before J.Phys.A publicatio

Local scale invariance in the parity conserving nonequilibrium kinetic Ising model

The local scale invariance has been investigated in the nonequilibrium kinetic Ising model exhibiting absorbing phase transition of PC type in 1+1 dimension. Numerical evidence has been found for the satisfaction of this symmetry and estimates for the critical ageing exponents are given.Comment: 8 pages, 2 figures (IOP format), final form to appear in JSTA

Non-Markovian Persistence at the PC point of a 1d non-equilibrium kinetic Ising model

One-dimensional non-equilibrium kinetic Ising models evolving under the competing effect of spin flips at zero temperature and nearest neighbour spin exchanges exhibiting a parity-conserving (PC) phase transition on the level of kinks are investigated here numerically from the point of view of the underlying spin system. The dynamical persistency exponent $\Theta$ and the exponent $lambda$ characterising the two-time autocorrelation function of the total magnetization under non-equilibrium conditions are reported. It is found that the PC transition has strong effect: the process becomes non-Markovian and the above exponents exhibit drastic changes as compared to the Glauber-Ising case.Comment: 6 pages, Latex, postscript figures include

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design

Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new drugs, which bind to calmodulin as a target. We present available structural information on the protein, obtained by X-ray diffraction, nuclear magnetic resonance spectroscopy and molecular modeling and try to derive some conclusions on structureactivity relationships