Qualitätsstandards zur Entwicklung, Anwendung und Bewertung von Messinstrumenten in der sozialwissenschaftlichen Umfrageforschung

Der vom Bundesministerium für Bildung und Forschung (BMBF) geförderte Rat für Sozial- und Wirtschaftsdaten (RatSWD) berät seit 2004 die Bundesregierung und die Regierungen der Länder in Fragen der Erweiterung und Verbesserung der Forschungsinfrastruktur für die empirischen Sozial-, Wirtschafts- und Verhaltenswissenschaften (SWV). Ende 2010 hat sich der RatSWD der Fragestellung gewidmet, wie sich die Qualität von Erhebungsinstrumenten in den Sozial- und Wirtschaftswissenschaften, insbesondere in der entsprechenden Umfrageforschung prüfen und sichern lässt. Der RatSWD hat daher auf seiner Sitzung am 9. November 2012 beschlossen, eine Arbeitsgruppe Qualitätssicherung von Erhebungsinstrumenten unter Leitung von Prof. Rammstedt einzurichten. Insbesondere war die Berufung der Arbeitsgruppe mit dem Wunsch verbunden, Qualitätsstandards zu definieren, um hierdurch die Qualität zu sichern und zu optimieren. Die Arbeitsgruppe hat sich die Formulierung dieser Standards zum primären Ziel gesetzt. Die vorliegende Publikation stellt diese Standards dar

Increased metabolic activity of leukocytes in AMS-susceptibles

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Quality standards for the development, application, and evaluation of measurement instruments in social science survey research

Since its establishment in 2004, the German Data Forum (RatSWD), which is funded by the German Federal Ministry of Science and Research (BMBF), has been advising the federal government and the governments of the federal states (Länder) on issues relating to the expansion and improvement of the research infrastructure for the empirical social, behavioral, and economic sciences (SBE). In late 2010, the RatSWD addressed the question of how the quality of survey instruments in the social and economic sciences, and especially in social and economic survey research, could be controlled and assured. At a meeting on November 9, 2012, the RatSWD therefore decided to set up a Quality Assurance of Survey Instruments Working Group under the leadership of Professor Beatrice Rammstedt. The establishment of the working group was prompted in particular by the desire to define quality standards in order to assure and optimize the quality of survey instruments. Hence, the working group made the formulation of these standards its primary objective. They are presented in this paper

Indirect markers of pulmonary endothelial function correlate with pulmonary artery pressure at high altitude

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No change of lung volumes and compliance measured by body pletzysmography in AMS at 4559 m

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Endothelin receptors upregulated in circulating endothelial cells in HAPE?

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Transpulmonary plasma ET-1 and nitrite differences in high altitude pulmonary hypertension.

Berger, Marc M. Christoph Dehnert, Damian M. Bailey, Andrew M. Luks, Elmar Menold, Christian Castell, Guido Schendler, Vitalie Faoro, Heimo Mairbäurl, Peter Bärtsch, and Eric R. Swenson. Transpulmonary plasma ET-1 and nitrite differences in high altitude pulmonary hypertension. High Alt. Med. Biol. 10:17-24, 2009.- Thirty-four mountaineers were studied at low (110 m) and high altitude (4559 m) to evaluate if increased pulmonary artery systolic pressure (PASP) at high altitude is associated with increased pulmonary endothelin-1 (ET-1) availability and alterations in nitrite metabolism across the lung. Blood samples were obtained using central venous and radial artery catheters for plasma ET-1 and nitrite. Pulmonary blood flow was measured by inert gas rebreathing to calculate transpulmonary exchange of plasma ET-1 and nitrite, and PASP was assessed by transthoracic Doppler echocardiography. After ascent to high altitude, PASP increased from 23 +/- 4 to 39 +/- 10 mmHg. Arterial and central venous plasma ET-1 increased, while plasma nitrite did not change significantly. At low altitude there was a transpulmonary loss of plasma ET-1, but a transpulmonary gain at high altitude. In contrast was a transpulmonary gain of plasma nitrite at low altitude and a transpulmonary loss at high altitude. PASP positively correlated with a transpulmonary gain of plasma ET-1 and negatively correlated with a transpulmonary loss of plasma nitrite. These results suggest that a transpulmonary gain of plasma ET- 1 is associated with higher PASP at high altitude. Transpulmonary loss of plasma nitrite indicates either less pulmonary nitric oxide (NO) production, which contributes to higher PASP, or increased NO bioavailability arising from nitrite reduction, which may oppose ET-1-mediated vasoconstriction.Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe