Acid-Induced Multicolor Fluorescence of Pyridazine Derivative

Smart luminescent materials that are responsive to external stimuli have received considerable attention. Here, we report a new D–A type 1,2-pyridiazine derivative (3,4,5,6-tetrakis­(4-methoxyphenyl)­pyridazine (<b>TPP</b>)) exhibiting turn-on fluorescence upon acid exposure both in solution and in the solid state. The protonation of the 1,2-pyridiazine ring caused a variation in the emission colors of the acidification species from blue (406 nm) to orange-red (630 nm) with a huge Δλ_em (224 nm). As a result, a synthetic rainbow of emission in solution could be achieved from one single molecule, and white photoluminescence was readily tuned by controlled protonation. A trifluoroacetic acid (TFA)-sensor film made from <b>TPP</b> was demonstrated as a TFA-sensitive surface with high sensitivity and reversibility. On the basis of these findings, we constructed a solid-state <b>TPP</b> film with a photoacid generator and demonstrated data encryption and decryption via a cascade protonation reaction that was well controlled by UV light

Controllable Fabrication of Pyramidal Silicon Nanopore Arrays and Nanoslits for Nanostencil Lithography

This paper presents a controllable method for the high-throughout fabrication of pyramidal silicon nanopore arrays (PSNAs). Using this method, square nanopore arrays with an average size of 60 nm, rectangular nanopores with different length–width ratios, and nanoslits with feature sizes as small as 13 nm were created. Focused ion beam (FIB) cutting experiments showed that the inner structure of the nanopore was exactly pyramidal, which offered unique ionic rectification properties. Moreover, preliminary nanostencil lithography experiments indicated that such PSNAs could be used as reusable masks to directly deposit large-scale surface patterns in both nano and micro scales, and with less time and low cost

Thiophene-Fused 1,10-Phenanthroline and Its Conjugated Polymers

A novel type of π-extended 1,10-phenanthroline, specifically with fused thiophene groups at the less exploited 3-, 4-, 7-, and 8-positions of the phenanthroline ring, and its conjugated polymers were designed and synthesized. The current developed route is based on the Bischler–Napieralski cyclization of the (1,2-phenylene)­diamide precursor, which offers a facile and versatile strategy for preparing soluble and well-defined 1,10-phenanthroline derivatives and their analogues. High molecular weight poly­(phenanthroline-<i>co</i>-fluorene)­s with good solubility in common organic solvents or water were prepared by palladium-catalyzed Suzuki–Miyaura–Schlüter polycondensation. The optical responsive properties of these thiophene-fused 1,10-phenanthroline-containing polymers have demonstrated these polymers could be a good candidate for potential applications as luminescent chemosensor materials thanks to the specific repeating unit along the backbone

Thiophene-Fused 1,10-Phenanthroline and Its Conjugated Polymers

A novel type of π-extended 1,10-phenanthroline, specifically with fused thiophene groups at the less exploited 3-, 4-, 7-, and 8-positions of the phenanthroline ring, and its conjugated polymers were designed and synthesized. The current developed route is based on the Bischler–Napieralski cyclization of the (1,2-phenylene)­diamide precursor, which offers a facile and versatile strategy for preparing soluble and well-defined 1,10-phenanthroline derivatives and their analogues. High molecular weight poly­(phenanthroline-<i>co</i>-fluorene)­s with good solubility in common organic solvents or water were prepared by palladium-catalyzed Suzuki–Miyaura–Schlüter polycondensation. The optical responsive properties of these thiophene-fused 1,10-phenanthroline-containing polymers have demonstrated these polymers could be a good candidate for potential applications as luminescent chemosensor materials thanks to the specific repeating unit along the backbone

Na Wu-corvis primary data

Na Wu-corvis primary dat

Low-Triggering-Potential and Narrow-Potential-Window Electrochemiluminescence of Silver Nanoclusters for Gene Assay

A low-triggering potential and a narrow-potential window are anticipated to decrease the electrochemical interference and cross talk of electrochemiluminescence (ECL). Herein, by exploiting the low oxidative potential (0.82 V vs Ag/AgCl) of dihydrolipoic acid-capped sliver nanoclusters (DHLA-AgNCs), a coreactant ECL system of DHLA-AgNCs/hydrazine (N2H4) is proposed to achieve efficient and oxidative-reduction ECL with a low-triggering potential of 0.82 V (vs Ag/AgCl) and a narrow-potential window of 0.22 V. The low-triggering-potential and narrow-potential-window nature of ECL can be primarily preserved upon labeling DHLA-AgNCs to probe DNA and immobilizing DHLA-AgNCs onto the Au surface via sandwiched hybridization, which eventually enables a selective ECL strategy for the gene assay at +0.82 V. This gene assay strategy can sensitively determine the gene of human papillomavirus from 10 to 1000 pM with a low limit of detection of 5 pM (S/N = 3) and would open a way to improve the applied ECL bioassay

Type of topical PGA medications used in patients with POAG.

<p>Type of topical PGA medications used in patients with POAG.</p

Corneal biomechanical properties of POAG patients with long-term treatment of bimatoprost, latanoprost or travoprost.

<p>Corneal biomechanical properties of POAG patients with long-term treatment of bimatoprost, latanoprost or travoprost.</p

Tuning the Mechanochromic Luminescence of BOPIM Complexes by Rational Introduction of Aromatic Substituents

Considering the great advantages of boron 2-(2′-pyridyl)­imidazole (BOPIM) based dyes, such as facile synthesis, high fluorescence quantum yield, large Stokes shift, and good thermal stability, three BOPIM complexes (<b>BOMPIM-Ph</b>, <b>BOPIM-Th</b>, and <b>BOPIM-TTh</b>) with different aromatic side groups have been developed. Their crystal structures and photophysical and mechanochromic luminescence properties were systematically studied. It was found that their solid state emission and mechanochromic behaviors are related to the side group. High color contrast reversible mechanochromism and piezochromism were observed for the three analogues, while <b>BOPIM-TTh</b> with more bulky thienothiophene groups showed a more sensitive and pronounced mechanochromic response. Steric and electronic effects of the aromatic donating substitutes were proved playing significant roles in regulating the intermolecular interactions and intramolecular charge transfer effect. Fine-tuning the molecular structures of such kind of BOPIM dyes allows convenient modulation of their optical properties and mechano-responsive behaviors

Box-and-whisker plot of the mean AT1 (A), AV1 (B), AT2 (C), AV2 (D) and DA (E) in the normal, glaucoma without PGA treatment and glaucoma with long-term PGA treatment groups.

<p>Black squares and thin error bars represent means and maximum/minimum values, respectively. General linear model analysis was performed to investigate the corneal biomechanical property changes among the 3 subgroups. Furthermore, pairwise comparisons using Bonferroni correction for least squares means were employed.</p