916 research outputs found

    The Effect of Customization Service on Flow Experience and Behavior Intensions in Customer Co-Design Process

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    Computer Mediated Environments (CMEs) prepared a satisfactory opportunity for providing customization service on line. This characteristics of synchronous and interactive allow designers or enterprises enhance to discover customer s’ demands. Interface design plays a core role and influence customers’ decisions. Yet, the research of this field also has varied investigation about “flow experience”, which considerable attention has been paid in the past to research issues related to motionless state of customization product process in CMEs (e.g. system, technology, and communication tool et al.), a literature on issues of dynamic state has emerged only very slowly and in a more scattered way. It excited the curiosity of this study In this study, we attempt evaluate customization improvements of customer value by content customization and context customization. Further to investigate the relationships between content and context customization, flow experience and behavioral intentions when provide customer co-design service. According the findings, content customization service and context customization service provided enhanced the flow experience occur. Yet, the flow experience was significantly associated with behavior intension

    Toward Kansei Engineering Model in Service Design: Interaction for Experience in Virtual Learning Environment

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    Service design is an emerging trend shifting from product design era. Internet provides effective and efficient service media reaching customer at the exact time. Online media has become social network providing wide opportunity for business, pleasures, and education. This study is focusing on applying kansei engineering model for service design in virtual learning environment (VLE) as learning is concerning with experiencing the process. Various virtual world studies discover that VLE can provide powerful experience in learning. On the other hand, learning styles and learning space potentially enhance experiential learning. Experiential learning theory defines learning process as transformation process from experience to knowledge. Experience is one of important element in service design principle. In addition, experience can be engineered by utilizing kansei engineering approach. Therefore, experience can be designed and engineered to achieve knowledge as service result. This study expected can guide service designers and learning curriculum designer in designing effective experiential learning method. The model developed from the analyzing and reviewing literature shows that kansei engineering can be utilized in experiential transformation process into knowledge and also in service in learning theory context

    A Study of the Cognition-Action Gap in Knowledge Management

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    We investigated three types of volitional control mechanisms that may impact people’s knowledge management (KM) practices. Our results show that, when employing KM, people do not always perform in a manner consis- tent with their beliefs concerning attitudes and intentions. This cognition-behavior inconsistency can be ex- plained by volitional control mechanisms. Specifically, both perceived self-efficacy (Bandura 1997) and action control (Kuhl and Bechmänn 1985) play a role in motivating individuals to share and use knowledge, while perceived behavioral control does not. In addition, action/state orientation moderates a person’s enactment of subjective norm and self-efficacy beliefs into intentions just as it moderates enactment of perceived behavioral control belief into behaviors. These results have important theoretical and managerial implication

    Late onset of large benign ductus arteriosus aneurysm presented with increased nuchal translucency and cystic hygroma at first trimester Down syndrome screening

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    AbstractObjectiveFetal ductus arteriosus aneurysm (DAA) is a rare but potentially risky congenital heart disease. It is often not diagnosed until the third trimester because of its asymptomatic nature and late onset. In rare occasions, DAA may result in serious complications; therefore, prenatal diagnosis is helpful.Case ReportHerein, we report the case of a foetus with cystic hygroma and increased nuchal translucency in the first trimester (but regressed at 20-week anomalous scan). Karyotyping indicated a 46 XY genotype. A large vascular mass was noted at the apex of the left lung by Doppler ultrasound at 38 weeks of gestation, with a diameter of 12.5 mm. After birth, echocardiography showed a patent ductus arteriosus with aneurysmal dilatation (17 mm as the largest diameter); thus, DAA was impressed. Chest computed tomography and three-dimensional angiography confirmed the large aneurysmal dilatation of the ductus arteriosus with a closed end at the pulmonary arterial side.ConclusionThe male infant survived, but presented mild respiratory distress at birth. He was discharged at 24 days of age. At that time, DAA had regressed partially (diameter of 8.5 mm and much less blood flow), and it fully regressed at 40 days of age

    A pharmacogenetic study of perampanel: association between rare variants of glutamate receptor genes and outcomes

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    Introduction: The selection of antiseizure medication usually requires a trial-and-error process. Our goal is to investigate whether genetic markers can predict the outcome of perampanel (PER) use in patients with epilepsy.Method: The studied participants were selected from our previous epilepsy genetics studies where whole exome sequencing was available. We reviewed the medical records of epilepsy patients older than 20 years old treated with PER. The outcome of PER treatment included the response to PER, the occurrence of any adverse drug reaction (ADR), the presence of behavior ADR, and the ability to adhere to PER for more than 1 year. We investigated the association between the rare variants of the glutamate receptor genes and the outcomes of PER use.Result: A total of 83 patients were collected. The gene group burden analysis showed that enriched genetic variants of the glutamate receptor gene group were statistically significantly associated with the occurrence of ADR, while the glutamate ionotropic receptor delta type subunit had a nominal association with the occurrence of ADR. The gene collapse analysis found that GRID1 had a nominal association with the occurrence of ADR and GRIN3A had a nominal association with the occurrence of behavior ADR. However, these nominal associations did not remain statistically significant once adjusted for multiple testing.Discussion: We found that enriched rare genetic variants of the glutamate receptor genes were associated with the occurrence of ADR in patients taking PER. In the future, combining the results of various pharmacogenetic studies may lead to the development of prediction tools for the outcome of antiseizure medications
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