Survey on Hybrid Anonymization using k-anonymity for Privacy Preserving in Data Mining

K-anonymity is the one of the popular privacy preserving model. In the data mining there is multiple technique is available k-anonymity is one of the technique which is used for the protecting privacy in the database. In this paper our main approach is hybrid anonymization. The main thing of this technique is that it is the mixing of two techniques. We introduce hybrid anonymization with hybrid generalization which is formed by not only generalization but also the data relocation. Data relocation serves trade-off between truthfulness and utility. Using the hybrid anonymization we maintain the privacy standard such as k-anonymity. In the previous research we find that k-anonymity is not good work with multiple sensitive data and there is more information loss occurs for that issue we use hybrid anonymization on multiple dataset. We show that our model can decrease the information loss in minimum time period

Review - Improve Performance of Efficient Aggregation Scheduling In Multihop Wireless Sensor Network

The aggregated scheduling of data in networks of wireless sensors with interference of signal with SINR limitations is studied. A routing tree is formulated hat provides an overview of scheduling algorithms by which schemas of interlinking that are free of collision for clustering of data. The latency of algorithm that is suggested is improvised of IAS & DAS. The delay counted n every algorithm is O(R + ?) in time-slots, where ? & R are radius of graph & the extreme degree of node in a minimized graph communication of the real network, are optimized in sensors which are wireless. It is observed that throughput of algorithms suggested in enhanced than that of CIAS & CDAS

ANTIOXIDANT AND ANTIULCER ACTIVITY OF ABRUS PRECATORIUS LEAF EXTRACT AGAINST ACETIC ACID-INDUCED GASTRIC ULCER IN RATS

Objective: The present study deals with the study of antiulcer activity of Abrus precatorius leaf extract in acetic acid-induced gastric ulcers was studied in rats. Methods: In the present study, A. precatorius leaf extract was carried out in antiulcer activity against acetic acid-induced gastric ulcer in rats. A. precatorius at doses of 150 mg/kg and 300 mg/kg were administered orally once daily for 10 days. Results: It was found that extract significantly reduced ulcer index. The plant leaves made gastric anti-secretory effect by decreasing gastric volume and acidity. Then, gastric mucin was increased, which showed gastric cytoprotective effect. The plant showed the prevention effect of increased lipid peroxidation during ulceration by acetic acid. Activities of the antioxidant enzymes were enhanced during ulceration by this plant leaves. Conclusion: Leaves of A. precatorius Linn. could decrease acetic acid-induced gastric ulcers in rats and this antiulcerogenic activity was mediated through antioxidant defense mechanism

Comparison of the Effects of Zonisamide, Ethosuximide and Pregabalin in the Chronic Constriction Injury Induced Neuropathic Pain in Rats

Background: Evidence has been generated that various anticonvulsant agents provide relief of several chronic pain syndromes and therefore as an alternative to opioids, nonsteroidal anti.inflammatory, and tricyclic antidepressant drugs in the treatment of neuropathic pain. The results of these studies thus raise the question of whether all anticonvulsant drugs or particular mechanistic classes may be efficacious in the treatment of neuropathic pain syndromes.Aim: The aim was to compare the clinically used anticonvulsant drugs which are differ in their mechanism of action in a chronic pain model, the chronic constriction injury, in order to determine if all anticonvulsants or only particular mechanistic classes of anticonvulsants are analgesic.Materials and Methods: The study included zonisamide, ethosuximide and pregabalin. All compounds were anticonvulsant with diverse mechanism of actions. The peripheral neuropathic pain was induced by chronic constriction injury of the sciatic nerve in male Sprague.Dawley rats. Zonisamide (80 and 40 mg/kg), ethosuximide (300 and 100 mg/kg), pregabalin (50 and 20 mg/kg), and saline was administered intraperitoneally in respective groups in a blinded, randomized manner from postoperative day (POD) 7.13. Paw withdrawal duration to spontaneous pain, chemical allodynia and  mechanical hyperalgesia and paw withdrawal latency to mechanical  allodynia and thermal hyperalgesia were tested before drug administration on POD7 and after administration on POD 7, 9, 11 and 13.Results: The present study suggests that these drugs could provide an effective alternative in the treatment of neuropathic pain. However, zonisamide and pregabalin appears to have suitable efficacy to treat a wide spectrum of neuropathic pain condition. Conclusion: The present findings suggest that the inhibition of N.type calcium channels or voltage.gated sodium and T.type calcium channels provides better analgesic potential instead of inhibition of T.type calcium channels alone.Keywords: Chronic constriction injury model, Ethosuximide, Neuropathic pain, Pregabalin, Zonisamid

Cationic Guar Gum as a depressor for a Gangue in froth flotation of Pyritic-zinc ore from Rajpura Dariba Mines, Udaipur, India

Flotation in one of the important operations in ore beneficiation process. Chemical auxilliaries play an important role in the froth flotation process 1. In order to obtain a successful flotation of slimy sulphide ores, two types of chemical auxilliaries are basically in use i. e. ( i ) a hydrocolloid acting as flocculent for gangue material, commonly referred as a depressor and (ii) a collector or a metal reagent, which conditions the mineral surface ( by adsorption and making it more hydrophobic ) so that it will rise to the surface when a frother is added. Besides these, certain other chemicals are also sometimes used to augment the action of either depressor or collector 2

Maximization of seed yield in transplanted fennel (Foeniculum vulgare Mill.)

A field experiment was conducted at Udaipur (Rajasthan) to study the effect of three plantdensities, four fertilizer treatments and two growth regulators on yield maximization oftransplanted fennel (Foeniculum vulgare).  Planting of fennel at a density of 27,770 plants ha-1recorded significantly higher yield attributes (umbels plant-1, seed yield plant-1 and test weight),while seed yield ha-1 was higher with a density of 55,550 plants ha-1 (20.89 q ha-1).  Applicationof 90 kg N + 40 kg P2O5 + 20 kg K2O + 20 kg S + 5 kg Zn ha-1 recorded significantly higher yieldattributes and yield of fennel during both the years.  Application of naphthalene acetic acid100 ppm recorded significantly higher yield attributes and seed yield. &nbsp

Phytopharmaceuticals and In-Vitro Antioxidant Potentials of Soyabean Methonolic Extract

Soyabean methanolic extract were used for investigation of phytopharmaceuticals and antioxidant potentials. The extract was analyzed for total phenolic compound, total flavonoid compound, reducing power, hydrogen peroxide and DPPH assay. The results depicted that the methonolic extract have broad range of antioxidants present in it. Keywords: phytopharmaceuticals, Soyabean methanolic extract, antioxidan

FORMULATION AND EVALUATION OF ORAL FLOATABLE IN-SITU GEL OF RANITEDINE HYDROCHLORIDE

Objective: The present investigation deals with the formulation, optimization and evaluation of sodium alginate based floating oral In situ gel of Ranitedine HCl. Sodium alginate used as a polymer and CaCO3 was used as a cross-linking agent. In-situ forming polymeric formulation drug delivery systems is in sol form before administration in the body, but once administered, undergoes gelation in-situ to form a gel. The formulation of gel depends upon factors like temperature modulation, pH changes, presence of ions and ultraviolet irradiation from which drug gets released in sustained and controlled manner. Methods: The objective of this study was to develop a novel in- situ gel system for sustained drug delivery using natural biodegradable polymers. The system utilizes polymers that exhibit sol-to-gel phase transition due to change in specific physicochemical parameters. Results: In-situ gel was formed at a gastric pH from designed set of experiments, it was evident that formulation containing 2 % of sodium alginate control the release of drug for longer duration. The in-situ gel exhibited the expected, viscosity, drug content, pH, in vitro gelling capacity, in vitro floating ability and sustained drug release. Conclusion: The formulated in situ gel for Ranitedine Hydrochloride was found to be stable in situ gel. It was found to have better floating efficacy and in vitro release profile characteristics. Better efficiency and results of batch F-6 gives newer alternative use of natural biodegradable polymers in situ gel formulation. Key Words: Oral In-situ gel, Sustained Release. Sodium alginate, Calcium Carbonate, Ranitedine HCl

Combined Tumor Cell-Based Vaccination and Interleukin-12 Gene Therapy Polarizes the Tumor Microenvironment in Mice

Tumor progression depends on tumor milieu, which influences neovasculature formation and immunosuppression. Combining immunotherapy with antiangiogenic/antivascular therapy might be an effective therapeutic approach. The aim of our study was to elaborate an anticancer therapeutic strategy based on the induction of immune response which leads to polarization of tumor milieu. To achieve this, we developed a tumor cell-based vaccine. CAMEL peptide was used as a B16-F10 cell death-inducing agent. The lysates were used as a vaccine to immunize mice bearing B16-F10 melanoma tumors. To further improve the therapeutic effect of the vaccine, we combined it with interleukin (IL)-12 gene therapy. IL-12, a cytokine with antiangiogenic properties, activates nonspecific and specific immune responses. We observed that combined therapy is significantly more effective (as compared with monotherapies) in inhibiting tumor growth. Furthermore, the tested combination polarizes the tumor microenvironment, which results in a switch from a proangiogenic/immunosuppressive to an antiangiogenic/immunostimulatory one. The switch manifests itself as a decreased number of tumor blood vessels, increased levels of tumor-infiltrating CD4+, CD8+ and NK cells, as well as lower level of suppressor lymphocytes (Treg). Our results suggest that polarizing tumor milieu by such combined therapy does inhibit tumor growth and seems to be a promising therapeutic strategy

Developing Pavement-Safety Based Guidelines for Improving Horizontal Curve Safety

Inadequate skid resistance on wet pavements, specifically on horizontal curves of rural highways, is responsible for vehicle crashes and fatalities. Several research projects have developed models that project the effect of various geometric and pavement parameters on skid resistance. This study is an attempt to revise an existing model proposed by Texas A&M Transportation Institute (TTI) researchers. The proposed model is based on pavement parameters including (mix type, gradation, aggregate parameters and traffic parameters). Laboratory and field tests (circular track meter (CTM), dynamic friction tester (DFT), 3-wheel polisher, micro-deval test, aggregate image measuring system (AIMS) and skid trailer test) were conducted on various treatment sites, aggregate types and mix types to analyze their performance and effects on skid resistance. Data used for this study include the data collected from laboratory and field tests, data from TxDOT pavement management information system (PMIS) along with data from past research. This study is a contribution to revise some equations in an existing skid prediction model and to develop a database consisting of skid related data which would help practitioners in taking pavement-safety related decisions on horizontal curves