Las representaciones artísticas de los «Cuetos Pardos» (Cabrales, Asturias): identificación, estudio preliminar, y planteamientos para resolver un enigma

The aim of this paper is to describe a group of engravings and paintings discovered in a rocky outcrop of eastern Asturias. This first analysis of the panel allowed us to know the main features of the art motifs that, nowadays, don’t have an absolute dating associated. Apart from the analysis of the rock art the text addresses the prehistoric context, as well as the landscape in the surroundings of the rock. These are key data for a comprehensive view of the site, as well as for understanding the long roots of the prehistoric communities in this space.El presente texto da noticia detallada de la localización de un conjunto de motivos pintados y grabados en una formación rocosa de la zona oriental de Asturias. El estudio preliminar del panel permite conocer en detalle las características de las muestras artísticas que, de momento, carecen de referencias cronológicas absolutas. Acompañando el análisis del panel se incluye una contextualización prehistórica y paisajística que permite entender no solo el paraje en el que se encuentran las figuras, sino también el largo anclaje prehistórico al lugar

Las representaciones artísticas de los «Cuetos Pardos» (Cabrales, Asturias): identificación, estudio preliminar, y planteamientos para resolver un enigma

The aim of this paper is to describe a group of engravings and paintings discovered in a rocky outcrop of eastern Asturias. This first analysis of the panel allowed us to know the main features of the art motifs that, nowadays, don’t have an absolute dating associated. Apart from the analysis of the rock art the text addresses the prehistoric context, as well as the landscape in the surroundings of the rock. These are key data for a comprehensive view of the site, as well as for understanding the long roots of the prehistoric communities in this space.El presente texto da noticia detallada de la localización de un conjunto de motivos pintados y grabados en una formación rocosa de la zona oriental de Asturias. El estudio preliminar del panel permite conocer en detalle las características de las muestras artísticas que, de momento, carecen de referencias cronológicas absolutas. Acompañando el análisis del panel se incluye una contextualización prehistórica y paisajística que permite entender no solo el paraje en el que se encuentran las figuras, sino también el largo anclaje prehistórico al lugar

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective