RELAPSE OF GUILLAIN-BARRE SYNDROME AFTER SPINAL ANESTHESIA: A CASE REPORT

Guillain-Barre Syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy characterized by progressive symmetric ascending muscle weakness, paralysis and hyporeflexia with or without sensory or autonomic symptoms. It is most commonly caused by an autoimmune response of the body to an infectious agent like Campylobacter jejuni. It is less common during pregnancy but it may relapse during postpartum period. Cases of GBS have been reported after Spinal, epidural and general anesthesia. Here we report a case of 28year old female patient who had relapse of GBS after undergoing emergency laparotomy for ruptured ectopic pregnancy. In this case report, we are presenting an unusual case of GBS relapsing 4 years after initial episode following spinal anesthesia.KEYWORDS: Guillain-Barre Syndrome; Campylobacter jejuni; Postpartum period

RELAPSE OF GUILLAIN-BARRE SYNDROME AFTER SPINAL ANESTHESIA: A CASE REPORT

Guillain-Barre Syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy characterized by progressive symmetric ascending muscle weakness, paralysis and hyporeflexia with or without sensory or autonomic symptoms. It is most commonly caused by an autoimmune response of the body to an infectious agent like Campylobacter jejuni. It is less common during pregnancy but it may relapse during postpartum period. Cases of GBS have been reported after Spinal, epidural and general anesthesia. Here we report a case of 28year old female patient who had relapse of GBS after undergoing emergency laparotomy for ruptured ectopic pregnancy. In this case report, we are presenting an unusual case of GBS relapsing 4 years after initial episode following spinal anesthesia.KEYWORDS: Guillain-Barre Syndrome; Campylobacter jejuni; Postpartum period

Comparative Evaluation of Effectiveness of Rocuronium Bromide vs. Succinyl Choline on Quality of Intubating Conditions during General Anesthesia

Objectives: To compare the quality of intubating conditions and hemodynamic responses to the administration of Rocuronium Bromide and Succinyl Choline during general anesthesia. Methods: This was a comparative study conducted at the anesthesiology department of a tertiary care medical college. Sixty patients undergoing various surgeries under general anesthesia were included in this study based on predefined inclusion and exclusion criteria. Patients were divided into Group S (receiving succinylcholine) and Group R (receiving rocuronium). In all patients, the quality of intubating conditions was assessed. Excellent or good conditions were considered to be acceptable intubating conditions, whereas fair and poor conditions were considered unacceptable. Results: Mean age, weight, gender distribution, and ASA grades were comparable in both groups. The overall quality of intubation was found to be better in group S than in group R, and the difference was statistically significant (P=0.004). The duration of action was significantly longer in group R than in group S (P<0.001). Hemodynamic stability was comparable in both the groups, except for heart rate at 10 min, which was higher in Group R than in Group S. Incidence of fasciculation was significantly more in Group S as compared to Group R, and the difference was found to be highly significant (P=0.0001). Conclusion: Succinylcholine for rapid sequence intubation is associated with better intubation conditions than rocuronium