30 research outputs found

    Interpretation of Airborne Magnetic Data of Upper Benue Trough, Northeastern Nigeria

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    Compilation of the airborne magnetic data was conducted by digitizing along the flight line, picking the contour values across each flight line over the upper Benue Trough, Northeastern Basement complex Nigeria. It shows complicated arrangement of long wavelength anomalies, with significant magnetic low. The study of airborne magnetic data revealed some features that are interpreted in terms of deep geologic structures with variation in susceptibility of the basement rocks of thick Cretaceous sediments. The NE-SW trending of the lineament map identifies the same trending of the Benue Trough. Such same trending may be inferred to have the same subsurface structural control. The residual magnetic anomaly map towards the SW region which is the location of Dong and Numan is smoother, which is masked off by the effect of the stronger magnetic basement likely to be a sedimentary basin. The NE-SW revelation shows that this basement region is polygenetic and has experienced magmatism, metamorphism, and structural deformations caused by Pan-Africa Orogeny

    Haematologic Indices in Pulmonary Tuberculosis with or without HIV Co-Infection in South Eastern Nigeria

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    To evaluate the changes in haematologic indices in patients with pulmonary tuberculosis (PTB) with or without Human Immune Deficiency Virus (HIV) co-infection in South Eastern Nigeria. The study population included 116 subjects (60 = males; 56 = females), recruited from 2 study centers: mile 4 Hospital Abakaliki Ebonyi State and Nnamdi Azikiwe University, Teaching  Hospital Nnewi, Anambra State, both in Nigeria. PTB + HIV (n = 20); PTB infection ( n = 27) and HIV sereopositive (n = 28). The PTB and HIV negative; control subjects were 41 (n = 41). Blood samples collected from subjects in Ethylene diamine tetra acetic acid (EDTA) container were used for the analysis of the Haemtological cells count,  packed cell volume (PCV) and Haemoglobin estimation using routine methods as described (Dacie and Lewis, 1984). HIV screening was done with Stat pak kit and confirmatory test by Western blot method. Erythrocyte sedimentation rate (ESR) was by Westergren method. Haemoglobin estimation (Hb), packed cell volume (PCV) values were significantly lower in patients with PTB (11.27±1.62 g/dl, 0.35±0.04 l/l) compared with control values (13.67±1.46 g/dl 0.41 ± 0.05 l/l) (p < 0.05). Patients with HIV seropositive showed significantly low PCV values of (0.36 ± 0.04 l/l) compared with the control subjects (0.41 ± 0.05 l/l) (p < 0.05). PTB patients showed higher TWBC counts (6062.5 ± 1481.83109/l) when compared those with HIV infection (3841.38±735.58 x 109/l) as well as normal control value (4363.64±551.66 x 109/l) (p < 0.05). Male and female values compared in this work showed no significant difference (p > 0.05). The results showed that the effect of PTB and HIV infection have caused some haematological deregulation. It also showed that sex has little or no effect on the studied parameters. Keywords: Pulmonary tuberculosis (PTB); Human ImmunoDeficiency Virus (HIV) and Hematologic Indice

    Preliminary report on magnetic susceptibility measurements on rocks within the Zaria granite batholith, Nigeria

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    Low field magnetic susceptibility measurements have been carried out within the Zaria granite batholith. The result has shown that magnetic susceptibility within the batholith varies between 29´10 -6 SI to 3506´10 -6 SI, with an average value of 684´10 -6 SI. The large variation in the measured values of the susceptibility is as a result of large variation of magnetic mineral content within an outcrop and the diversity of rock types within individual suite. Thin section observation of representative samples shows the major mineral to be feldspar, quartz and biotite, while magnetite, ilmenite and hematite occur as trace minerals. The frequency distribution shows a bimodal distribution, which is typical of granites due to a low-k peak for paramagnetic dominated specimens and high-k peak for magnetite/hematite dominated specimens. The occurrence of hematite and ilmenite may be due to the alteration of magnetite

    Packed cell volume and serum iron in subjects with HIV-malaria co-infection in Nnewi, South-Eastern Nigeria

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    The present study was designed to assess the PCV and serum iron in HIV-malaria co-infected subjects in Nnewi, South Eastern Nigeria. 207 participants aged between 16-72 (44 ± 28) years were recruited andclassified as follows based on standard screening and WHO criteria: (i) Asymptomatic HIV stage I subjects with or without malaria. (ii) Symptomatic HIV stage II subjects with or without malaria and not on (ART). (iii) HIV/AIDS subjects with or without malaria and on ART. (vi) HIV seronegative control subjects with or without malaria. Blood sample from these participants were analyzed for HIV seroreactivity, Plasmodium falciparum antigen, parasite density, serum iron concentrations and PCV using Standard Laboratory methods. The result showed that serum iron and PCV were significantly reduced amongst all the groups studied when compared with the control (

    Serum Lipid and Glucose Concentration in Relation to Some Physiological Varibles in College Students From Nnewi, Nigeria

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    Background: Serum lipid and glucose levels are largely determined by and or related to certain physical, physiological and biochemical parameters/variables. This study therefore, is aimed at determining the levels of serum lipid and glucose and the relationship between the serum lipid and glucose concentrations and the physical and physiological parameters/variables of apparently healthy individuals. Method: The blood samples of twenty-five medical students in the age range of 20 and 25 years were analyzed, for the serum glucose, total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDLc) levels after overnight fast, and LDLC calculated. Result: The mean serum glucose, HDLc, TC and LDLc were not significantly different in females and males students. The serum TG was however significantly lower in females than in the males (90.22 \ub1 25.17 vs. 116.93 \ub1 21.54 mg/dl; P< 0.05). Furthermore, females are significantly lower in weight than the males (61.2 \ub1 6.91 vs. 69.96 \ub1 9.30 kg; P< 0.05). Significant correlations were also recorded. Conclusion: The results presented showed that the slight difference seen in males and females was a factor of growth and diet and activity.Introduction :S\ue9rum lipide et niveau du glucose sont en grande partie d\ue9termin\ue9s par ou li\ue9s aux certains physique physiologique et variables/param\ue8tres biochimiques. Donc, l'objet de cette \ue9tude est de d\ue9terminer les niveaux de s\ue9rum lipide et du glucose et le rapport entre le s\ue9rum lipide et concentration du glucose et des variables/param\ue8tres physiques et physiologiques des individus apparemment en tr\ue8s bonne sant\ue9. M\ue9thodes : La prise de sang de vingt cinq \ue9tudiants en m\ue9decine dans la tranche d'\ue2ge de 20 - 25 ans ont \ue9t\ue9 \ue9tudi\ue9s pour le s\ue9rum glucose, cholest\ue9rol total (CT) triglyc\ue9ride (TG), et les niveaux de la densit\ue9 \ue9lev\ue9e du cholest\ue9rol lipoprot\ue9ines (HDLc) apr\ue8s un je\ufcne d'une nuit, et LDLc calcul\ue9. R\ue9sultats : Le s\ue9rum glucose, HDLc, TC et LDLc moyen n'\ue9taient pas sensiblement diff\ue9rents chez des \ue9tudiants du sexe f\ue9minin et masculin. Le s\ue9rum TG toutefois \ue9tait sensiblement inf\ue9rieur chez le sexe f\ue9minin et le sexe masculin (90,22+- 25,17 contre 116, 93+-21,54mg/dl ; P<0,05). Par ailleurs sexe f\ue9minin sont sensiblement inf\ue9rieurs en poids plus que chez le sexe masculin. (61,2+-6,91 contre 69,96+-9,30kg : P<0,05). Des corr\ue9lations importantes ont \ue9t\ue9 \ue9galement not\ue9es. Conclusion :À travers des r\ue9sultats, nous notons que la diff\ue9rence l\ue9g\ue8re vue chez le sexe masculin et le sexe f\ue9minin \ue9tait un facteur d'activit\ue9, d'alimentation et de la croissance

    Geoelectrical Investigation Of Aquifer Problems In Gosa Area Of Abuja, North Central, Nigeria

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    The study of aquifer problems in Gosa area of Abuja, North-central Nigeria, has been undertaken. Abuja, the capital city of Nigeria, is underlain by Precambrian basement rocks. Vertical electrical sounding (VES) was carried out at twelve locations within and around the Gosa area. The interpretation of the data obtained from the sounding revealed that six non-aquiferous geoelectrical layers overlie the unfractured basement. The first layer with average thickness of about 0.5 m and resistivity of 83 Ohmm. The thickness of the second layer is about 0.7 m and resistivity of 438 Ohm-m. The third layer is about 3.4 m thick and resistivity of about 63 Ohm-m. The fourth layer with average thickness of about 16.0 m and resistivity, 236 Ohm-m. The fifth layer with average thickness of 42.7 m and resistivity of about 68 Ohm-m. The thickness of sixth layer varies from 42.7 m to infinity and resistivity of about 2067 Ohm-m. Eight boreholes of varying depths, 45 to 70 m were drilled. Other areas were drilled with good yield of static water level of about 3.7 m, whereas Gosa aquifers were found dried. It could be attributed to basaltic intrusion that shattered the aquifer bearing rocks thereby devoid water in the zone after pronouncing from geophysical investigation

    EFFECT OF MAGNESIUM SUPPLEMENTATION ON PLASMA GLUCOSE IN PATIENTS WITH DIABETES MELLITUS

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    Magnesium depletion and/or deficiency are known feature of diabetes mellitus, and could lead to increased insulin resistance and diabetic complications. This study therefore looked at the potential benefit of magnesium administration on the management of diabetic mellitus. Twelve apparently healthy and 6 non-insulin dependent diabetic (NIDDM) subjects received 15mmol (360 mg) elemental magnesium as NUG2 (Meram Laboratories, France) in 500 ml of 0.9% saline intravenously over four hours. Blood samples were collected at baseline and at hourly intervals. The diabetic subjects had lower ionized (0.41±0.03 vs 0.48±0.01 mmoIAL; P< 0.05) and total (0.73±0.04 vs 0.88±0.02 mmol/L; P< 0.05) plasma magnesium concentrations than the non-diabetic subjects, reflecting a depletion of body magnesium. The administration of magnesium led to a significant increase in ionized and total plasma magnesium in both non-diabetic and diabetic subjects. Similarly, plasma glucose and insulin were significantly decreased, and homeostasis model assessment showed an increase in insulin sensitivity in diabetic subjects. In established cases of magnesium depletion and/or deficiency in diabetes mellitus, magnesium supplementation could be of great benefit in diabetic management

    Sex hormones and biochemical profiles of male gossypol users in South-West Nigeria

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    The present study was designed to evaluate the effects of gossypol administration on sex hormones and biochemical parameters of male subjects. Twelve male subjects receiving 20mg daily gossypol at the family planning clinic of University College Hospital, Ibadan were studied. Blood samples collected from the subjects before, at 16 weeks and 28 weeks of treatment with gossypol were used to determine the blood levels of sex hormones and biochemical parameters. There were significant reduction in spermatozoa count (P<0.01), motility (P<0.01) and testosterone concentration (P<0.01) but elevated concentrations of luteinizing hormone (LH) (P<0.05) and follicle stimulating hormone (FSH) (P<0.01) following treatment with gossypol. However, the seminal fluid volume was unchanged (P>0.05). Serum concentrations of sodium, potassium, transaminases, and alkaline phosphatases during the period of treatment showed a significant downward trend (P<0.05 in each case). Whereas there was no consistent pattern, in the serum concentrations of bilirubin, total protein and albumin. The findings of the present study suggest that gossypol is a potent male antifertility agent with capability of causing organ impairment

    Abnormal reproductive hormone profiles amongst infertile married women attending fertility support laboratory.

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    The present study was designed to use the reproductive hormone profiles to identify and classify infertility amongst married Nigerian women. 125 married women aged 20-38years; requiring laboratory investigations for reproductive hormone profile in order to determine the cause of their respective infertility were used. Serum levels of FSH, LH and progesterone were determined by Radioimmunoassay and the serum level of prolactin was determined by immunoradiometric assay. The results showed that 53 subjects (42%) were confirmed to be ovulating while 72(58%) were confirmed as having endocrine problems as the cause of infertility. The mean serum progesterone levels were significantly reduced in subjects identified as anovulatory of ovarian and idiopathic causes compared with corresponding level in the ovulating subjects,
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