The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids.

Trypanosomatid protozoa are unusual eukaryotes that are well known for having unusual ways of controlling their gene expression. The lack of a refined mode of transcriptional control in these organisms is compensated by several post-transcriptional control mechanisms, such as control of mRNA turnover and selection of mRNA for translation, that may modulate protein synthesis in response to several environmental conditions found in different hosts. In other eukaryotes, selection of mRNA for translation is mediated by the complex eIF4F, a heterotrimeric protein complex composed by the subunits eIF4E, eIF4G, and eIF4A, where the eIF4E binds to the 5'-cap structure of mature mRNAs. In this review, we present and discuss the characteristics of six trypanosomatid eIF4E homologs and their associated proteins that form multiple eIF4F complexes. The existence of multiple eIF4F complexes in trypanosomatids evokes exquisite mechanisms for differential mRNA recognition for translation

Quantum phase transitions and Berezinskii-Kosterlitz-Thouless temperature in a two-dimensional spin-orbit-coupled Fermi gas

We study the effect of spin-orbit coupling on both the zero-temperature and non-zero temperature behavior of a two-dimensional (2D) Fermi gas. We include a generic combination of Rashba and Dresselhaus terms into the system Hamiltonian, which allows us to study both the experimentally relevant equal-Rashba-Dresselhaus (ERD) limit and the Rashba-only (RO) limit. At zero temperature, we derive the phase diagram as a function of the two-body binding energy and Zeeman field. In the ERD case, this phase diagram reveals several topologically distinct uniform superfluid phases, classified according to the nodal structure of the quasiparticle excitation energies. Furthermore, we use a momentum dependent SU(2)-rotation to transform the system into a generalized helicity basis, revealing that spin-orbit coupling induces a triplet pairing component of the order parameter. At non-zero temperature, we study the Berezinskii-Kosterlitz-Thouless (BKT) phase transition by including phase fluctuations of the order parameter up to second order. We show that the superfluid density becomes anisotropic due to the presence of spin-orbit coupling (except in the RO case). This leads both to elliptic vortices and antivortices, and to anisotropic sound velocities. The latter prove to be sensitive to quantum phase transitions between topologically distinct phases. We show further that at a fixed non-zero Zeeman field, the BKT critical temperature is increased by the presence of ERD spin-orbit coupling. Subsequently, we demonstrate that the Clogston limit becomes infinite: $T_{\rm{BKT}}$ remains non-zero at all finite values of the Zeeman field. We conclude by extending the quantum phase transition lines to non-zero temperature, using the nodal structure of the quasiparticle spectrum, thus connecting the BKT critical temperature with the zero-temperature results.Comment: 17 pages, 7 figure

Effects of spin-orbit coupling on the Berezinskii-Kosterlitz-Thouless transition and the vortex-antivortex structure in two-dimensional Fermi gases

We investigate the Berezinskii-Kosterlitz-Thouless (BKT) transition in a two-dimensional (2D) Fermi gas with spin-orbit coupling (SOC), as a function of the two-body binding energy and a perpendicular Zeeman field. By including a generic form of the SOC, as a function of Rashba and Dresselhaus terms, we study the evolution between the experimentally relevant equal Rashba-Dresselhaus (ERD) case and the Rashba-only (RO) case. We show that in the ERD case, at fixed non-zero Zeeman field, the BKT transition temperature $T_{BKT}$ is increased by the effect of SOC for all values of the binding energy. We also find a significant increase in the value of the Clogston limit compared to the case without SOC. Furthermore, we demonstrate that the superfluid density tensor becomes anisotropic (except in the RO case), leading to an anisotropic phase-fluctuation action that describes elliptic vortices and antivortices, which become circular in the RO limit. This deformation constitutes an important experimental signature for superfluidity in a 2D Fermi gas with ERD SOC. Finally, we show that the anisotropic sound velocities exhibit anomalies at low temperatures, in the vicinity of quantum phase transitions between topologically distinct uniform superfluid phases.Comment: 5 pages, 3 figure

Bopp-Podolsky black holes and the no-hair theorem

Bopp-Podolsky electrodynamics is generalized to curved space-times. The equations of motion are written for the case of static spherically symmetric black holes and their exterior solutions are analyzed using Bekenstein's method. It is shown the solutions split-up into two parts, namely a non-homogeneous (asymptotically massless) regime and a homogeneous (asymptotically massive) sector which is null outside the event horizon. In addition, in the simplest approach to Bopp-Podolsky black holes, the non-homogeneous solutions are found to be Maxwell's solutions leading to a Reissner-Nordstr\"om black hole. It is also demonstrated that the only exterior solution consistent with the weak and null energy conditions is the Maxwell's one. Thus, in light of energy conditions, it is concluded that only Maxwell modes propagate outside the horizon and, therefore, the no-hair theorem is satisfied in the case of Bopp-Podolsky fields in spherically symmetric space-times.Comment: 9 pages, updated to match published versio

A model for structural defects in nanomagnets

A model for describing structural pointlike defects in nanoscaled ferromagnetic materials is presented. Its details are explicitly developed whenever interacting with a vortex-like state comprised in a thin nanodisk. Among others, our model yields results for the vortex equilibrium position under the influence of several defects along with an external magnetic field in good qualitative agreement with experiments. We also discuss how such defects may affect the vortex motion, like its gyrotropic oscillation and dynamical polarization reversal.Comment: 8 pages, resubmitted to Journal of Applied Physic