Имя Тудоръ в домонгольской Руси: христианское или скандинавское?

The personal name Tudorъ is attested for the first time in Old Russian sources in the treaty between Rus’ and Byzantium of 944 and it occurs later in chronicles, birchbark letters, and other written sources up to the end of the 12th century. It is traditionally interpreted as a variant of the Christian name Θεóδωρος/Fe(o)dorъ, although no Christian names are found among the roughly seventy personal names of the participants listed in the preamble to the treaty; the overwhelming majority of the names are Scandinavian. The name Tudorъ is much more satisfactorily derived from a popular Scandinavian anthroponym Þjóðarr. In the 11th‒12th centuries, it was widely used both by Old Russian nobility (not of Rurikid origin) and by ordinary inhabitants of the Novgorodian land. This name, however, began to be confused with the phonetically close Christian name Fedorъ/Feodorъ already in the 12th century: in a graffito in St. Sophia Cathedral in Kiev, the week dedicated to St. Theodor of Tyron (the first week of Great Lent) is called ‘Tudor’s week.’ In the 13th century the name Tudorъ fell out of usage because it was replaced by the Christian name Fedorъ/Feodorъ.Личное имя Тудоръ, впервые зафиксированное в русско-византийском договоре 944 г., происходит от распространенного древнескандинавского антропонима Þjóðarr. В XII в. оно широко употреблялось как в среде древнерусской элиты (но не представителями клана Рюриковичей), так и жителями Новгородской земли. В XIII в. это имя выходит из употребления, замененное фонетически сходным христианским Федоръ/Феодоръ

The Rehydration Ability of Whey Ingredients

The purpose of this research was to studythe ability of whey protein concentrates (WPC) and whey permeate produced with ultrafiltration of cheese whey to rehydrate. The products studied were cheese whey concentrate witha PDM percentage of 80% (WPC-80), and cheese whey permeate, both produced under the conditions of the PJSC Dairy “Voronezhsky”.WPC-80 and the whey permeate dissolution processes were studied using microscopy. Water-impermeable hydrophobic layers were formed at the boundary, preventing water penetration into dry particles. The result was a higher dissolution timeforWPC-80 compared with whey permeate. When WPC-80 came into contact with water,it initially formed an obtuse wetting angle with a slow change over time. Whey permeate reached the equilibrium wetting angle more quickly. Quickreconditioning of WPC moisture content required avoiding capillary penetration of water, which created a turbulent liquid flow. The application of these ingredients in different food industry areas can reduce the costs for finished products, contribute to cost-effectiveness, increase the total production, and reduce environmental risks. Keywords: whey protein concentrate, whey permeate powder, water-wetting, dissolutio

Technology for compiling supporting abstracts in the organization of students' independent work

In the conditions of modern Russian reality, higher educational institutions are faced with the need to train a highly qualified specialist capable of active independent activity. Speaking about independence, we note that this is one of the main features of a modern student and a future specialist, since the labor market needs employees who are fully prepared to solve professional problems, able to join professional activities immediately after graduation from higher school. Based on this need, higher education institutions try to build a learning process that can form a competent graduate who creatively applies his knowledge in practice. To do this, various innovative methods and tools are introduced into educational process. The purpose of the article is to analyze the experience of implementing the technology of making reference notes in the organization of independent work of students. The article presents an overview of the concept of "reference abstract" and "independent work", reveals the importance of independent work and features of its organization using reference notes. The study shows the possibilities of reference notes in the process of training students of pedagogical universities. The study revealed the performance of control and experimental groups in a professional course, one of the fundamental in the training of students of pedagogical universities. Using the questionnaire, the students ' assessment of the reference abstract technology influence on the independence was revealed. The implementation of the technology of reference notes in the organization of independent work of students allows you to expand the possibilities of training a modern highly qualified specialist

Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals

Secoisolariciresinol diglucoside (SDG), found mainly in flaxseed, is one of the essential lignans. SDG, as well as the beneficial fatty acid composition and high fiber content, has made flaxseed an important source of functional food or nutraceutical ingredients. Various studies have shown that SDG offers several health benefits, including protective effects against cardiovascular diseases, diabetes, cancer, and mental stress. These health benefits have been attributed to the antioxidant properties of SDG. Additionally, SDG metabolites, namely mammalian lignans, enterodiol and enterolactone, have shown promising effects against cancer. Therefore, understanding the biosynthetic pathway of SDG and its molecular mechanisms is a key to enable the production of new flaxseed cultivars rich in nutraceutical content. The present review highlights studies on the different health benefits of SDG, as well as lignan biosynthesis in flaxseed and genes involved in the biosynthetic pathway. Since SDG, the predominant lignan in flaxseed, is a glycosylated lignan, we also focus on studies investigating the genes involved in secoisolariciresinol glycosylation. These genes can be used to produce new cultivars with a novel level of glycosylation or lignan composition to maximize the yields of lignans with a therapeutic or protective potential

Genome of Linum usitatissimum convar. crepitans expands the view on the section Linum

Sequencing whole plant genomes provides a solid foundation for applied and basic studies. Genome sequences of agricultural plants attract special attention, as they reveal information on the regulation of beneficial plant traits. Flax is a valuable crop cultivated for oil and fiber. Genome sequences of its representatives are rich sources of genetic information for the improvement of cultivated forms of the plant. In our work, we sequenced the first genome of flax with the dehiscence of capsules—Linum usitatissimum convar. сrepitans (Boenn.) Dumort—on the Oxford Nanopore Technologies (ONT) and Illumina platforms. We obtained 23 Gb of raw ONT data and 89 M of 150 + 150 paired-end Illumina reads and tested different tools for genome assembly and polishing. The genome assembly produced according to the Canu—Racon ×2—medaka—POLCA scheme had optimal contiguity and completeness: assembly length—412.6 Mb, N50—5.2 Mb, L50—28, and complete BUSCO—94.6% (64.0% duplicated, eudicots_odb10). The obtained high-quality genome assembly of L. usitatissimum convar. crepitans provides opportunities for further studies of evolution, domestication, and genome regulation in the section Linum

Novel Photosensitizers Trigger Rapid Death of Malignant Human Cells and Rodent Tumor Transplants via Lipid Photodamage and Membrane Permeabilization

BACKGROUND: Apoptotic cascades may frequently be impaired in tumor cells; therefore, the approaches to circumvent these obstacles emerge as important therapeutic modalities. METHODOLOGY/PRINCIPAL FINDINGS: Our novel derivatives of chlorin e(6), that is, its amide (compound 2) and boronated amide (compound 5) evoked no dark toxicity and demonstrated a significantly higher photosensitizing efficacy than chlorin e(6) against transplanted aggressive tumors such as B16 melanoma and M-1 sarcoma. Compound 5 showed superior therapeutic potency. Illumination with red light of mammalian tumor cells loaded with 0.1 µM of 5 caused rapid (within the initial minutes) necrosis as determined by propidium iodide staining. The laser confocal microscopy-assisted analysis of cell death revealed the following order of events: prior to illumination, 5 accumulated in Golgi cysternae, endoplasmic reticulum and in some (but not all) lysosomes. In response to light, the reactive oxygen species burst was concomitant with the drop of mitochondrial transmembrane electric potential, the dramatic changes of mitochondrial shape and the loss of integrity of mitochondria and lysosomes. Within 3-4 min post illumination, the plasma membrane became permeable for propidium iodide. Compounds 2 and 5 were one order of magnitude more potent than chlorin e(6) in photodamage of artificial liposomes monitored in a dye release assay. The latter effect depended on the content of non-saturated lipids; in liposomes consisting of saturated lipids no photodamage was detectable. The increased therapeutic efficacy of 5 compared with 2 was attributed to a striking difference in the ability of these photosensitizers to permeate through hydrophobic membrane interior as evidenced by measurements of voltage jump-induced relaxation of transmembrane current on planar lipid bilayers. CONCLUSIONS/SIGNIFICANCE: The multimembrane photodestruction and cell necrosis induced by photoactivation of 2 and 5 are directly associated with membrane permeabilization caused by lipid photodamage

Proceedings of the Fifth Italian Conference on Computational Linguistics CLiC-it 2018

On behalf of the Program Committee, a very warm welcome to the Fifth Italian Conference on Computational Linguistics (CLiC-­‐it 2018). This edition of the conference is held in Torino. The conference is locally organised by the University of Torino and hosted into its prestigious main lecture hall “Cavallerizza Reale”. The CLiC-­‐it conference series is an initiative of the Italian Association for Computational Linguistics (AILC) which, after five years of activity, has clearly established itself as the premier national forum for research and development in the fields of Computational Linguistics and Natural Language Processing, where leading researchers and practitioners from academia and industry meet to share their research results, experiences, and challenges

Multidisciplinary technology of rehabilitation aims definition in patients with stroke on the basis of International Classification of Functioning, Disability and Health

Aim. To create and test an algorithm for rehabilitation goal setting based on international classification of functioning, disability and health (ICF) for patients with acute cerebral stroke. Materials and methods. The study included 75 patients. Rehabilitation was carried out at the first stage for patients in the acute phase of a stroke involving a multidisciplinary team, which included: neurologist, PRM, speech therapist, occupational therapist, physical therapist, clinical psychologist and nurse. For all patients, a rehabilitation diagnosis was established in the categories of ICF. Results. An algorithm of rehabilitation goal setting is based on the ICF and patient’s rehabilitation potential. Conclusions. The main element in the algorithm for determining the rehabilitation goal for a patient with cerebral stroke in the acute period is the selection of one of the most complex activities formulated by the multidisciplinary rehabilitation team in the categories of ICF activity and participation, and available to the patient by the end of the rehabilitation course. The goal of rehabilitation is established on the basis of a rehabilitation diagnosis at the conclusion of each specialist multidisciplinary team of the patient's recovery potential, and its definition is one of the most important technological components of rehabilitation