344 research outputs found
Stimulated Raman scattering in an optical parametric oscillator based on periodically poled MgO-doped stoichiometric LiTaO3
The evolution versus pump power of the spectrum of a singly resonant optical
parametric oscillator based on an MgO-doped periodically poled stoichiometric
lithium tantalate crystal is observed. The onset of cascade Raman lasing due to
stimulated Raman scattering in the nonlinear crystal is analyzed. Spurious
frequency doubling and sum-frequency generation phenomena are observed and
understood. A strong reduction of the intracavity Raman scattering is obtained
by a careful adjustment of the cavity losses.Comment: 6 figure
Psi-series solutions of the cubic H\'{e}non-Heiles system and their convergence
The cubic H\'enon-Heiles system contains parameters, for most values of
which, the system is not integrable. In such parameter regimes, the general
solution is expressible in formal expansions about arbitrary movable branch
points, the so-called psi-series expansions. In this paper, the convergence of
known, as well as new, psi-series solutions on real time intervals is proved,
thereby establishing that the formal solutions are actual solutions
Sub-kHz-level relative stabilization of an intracavity doubled continuous wave optical parametric oscillator using Pound-Drever-Hall scheme
We report the relative frequency stabilization of an intracavity frequency
doubled singly resonant optical parametric oscillator on a Fabry-Perot\'etalon.
The red/orange radiation produced by the frequency doubling of the intracavity
resonant idler is stabilized using the Pound-Drever-Hall locking technique. The
relative frequency noise of this orange light, when integrated from 1 Hz to 50
kHz, corresponds to a standard deviation of 700 Hz. The frequency noise of the
pump laser is shown experimentally to be transferred to the non resonant signal
beam
Pilot study of a brief provider and EMR-based intervention for overweight teens with asthma
INTRODUCTION: Asthma-related morbidity is increased in overweight patients, yet providers are given little guidance on how to discuss weight and asthma management with overweight teens.
OBJECTIVE: We piloted an electronic medical record (EMR)-based tailored discussion guide (TDG) and a brief provider training, to address weight management in overweight teens with asthma. The primary outcome was intervention impact on patient-reported asthma outcomes (e.g., asthma control and morbidity). Secondary outcomes included change in BMI, patient-centeredness, and change in healthy behaviors.
METHODS: Teens aged 13-18 years with persistent asthma and a body mass index ≥ 85th percentile for their age and sex were eligible. Parents of eligible teens were contacted before an upcoming appointment to allow teen enrollment during the clinic visit. Providers reviewed Motivational Interviewing (MI) concepts and were trained in the TDG for support of conversations around weight and asthma management. Measures included asthma outcomes retrieved from the EMR at 6- and 12-month post-baseline, teen impressions of patient-provider communication at 6-week post-enrollment, and teen report of healthy behaviors at 6- and 12-month post-baseline.
RESULTS: Of 44 teens enrolled (77% African-American, 63% female), mean BMI for intervention (n=25) and control groups (n=19) at baseline were similar. Thirty participants (68%) completed a 6-week questionnaire. Compared to controls, at 6 months, intervention teens reported fewer days of limited activity and uncontrolled asthma, but at 12 months, only restricted activity remained lower, and BMI was not reduced. Intervention teens reported clinic visits that were more patient-centered than controls, including discussion of asthma treatment options with provider, feeling ready to follow an asthma treatment routine, and receiving helpful tips about reaching a healthy weight. The healthy behavior dinner with family showed improvement for intervention teens at 6 and 12 months. The feasibility study also revealed a need to improve recruitment strategies and to streamline intervention delivery.
CONCLUSION: Modest improvements in patient-reported asthma outcomes and health behaviors were observed. There was strong evidence that the TDG supports provider discussion of weight and asthma to create a more patient-centered conversation from the perspective of participating teens. Challenges to recruitment and clinic adaptation must be addressed before advancing to a full-scale trial.
TRIAL REGISTRATION: NCT02575326 Teen Asthma Control Encouraging a Healthier Lifestyle, www.cllinicaltrials.gov
Stable two-dimensional solitary pulses in linearly coupled dissipative Kadomtsev-Petviashvili equations
A two-dimensional (2D) generalization of the stabilized Kuramoto -
Sivashinsky (KS) system is presented. It is based on the Kadomtsev-Petviashvili
(KP) equation including dissipation of the generic (Newell -- Whitehead --
Segel, NWS) type and gain. The system directly applies to the description of
gravity-capillary waves on the surface of a liquid layer flowing down an
inclined plane, with a surfactant diffusing along the layer's surface.
Actually, the model is quite general, offering a simple way to stabilize
nonlinear waves in media combining the weakly-2D dispersion of the KP type with
gain and NWS dissipation. Parallel to this, another model is introduced, whose
dissipative terms are isotropic, rather than of the NWS type. Both models
include an additional linear equation of the advection-diffusion type, linearly
coupled to the main KP-NWS equation. The extra equation provides for stability
of the zero background in the system, opening a way to the existence of stable
localized pulses. The consideration is focused on the case when the dispersive
part of the system of the KP-I type, admitting the existence of 2D localized
pulses. Treating the dissipation and gain as small perturbations and making use
of the balance equation for the field momentum, we find that the equilibrium
between the gain and losses may select two 2D solitons, from their continuous
family existing in the conservative counterpart of the model (the latter family
is found in an exact analytical form). The selected soliton with the larger
amplitude is expected to be stable. Direct simulations completely corroborate
the analytical predictions.Comment: a latex text file and 16 eps files with figures; Physical Review E,
in pres
Construction of Special Solutions for Nonintegrable Systems
The Painleve test is very useful to construct not only the Laurent series
solutions of systems of nonlinear ordinary differential equations but also the
elliptic and trigonometric ones. The standard methods for constructing the
elliptic solutions consist of two independent steps: transformation of a
nonlinear polynomial differential equation into a nonlinear algebraic system
and a search for solutions of the obtained system. It has been demonstrated by
the example of the generalized Henon-Heiles system that the use of the Laurent
series solutions of the initial differential equation assists to solve the
obtained algebraic system. This procedure has been automatized and generalized
on some type of multivalued solutions. To find solutions of the initial
differential equation in the form of the Laurent or Puiseux series we use the
Painleve test. This test can also assist to solve the inverse problem: to find
the form of a polynomial potential, which corresponds to the required type of
solutions. We consider the five-dimensional gravitational model with a scalar
field to demonstrate this.Comment: LaTeX, 14 pages, the paper has been published in the Journal of
Nonlinear Mathematical Physics (http://www.sm.luth.se/math/JNMP/
Constraints on new interactions from neutron scattering experiments
Constraints for the constants of hypothetical Yukawa-type corrections to the
Newtonian gravitational potential are obtained from analysis of neutron
scattering experiments. Restrictions are obtained for the interaction range
between 10^{-12} and 10^{-7} cm, where Casimir force experiments and atomic
force microscopy are not sensitive. Experimental limits are obtained also for
non-electromagnetic inverse power law neutron-nucleus potential. Some
possibilities are discussed to strengthen these constraints.Comment: 18 pages, 3 figure
Risk perception of arsenic exposure from rice intake in a UK population
In the UK, consumption of rice and rice-based products is on the rise but, notwithstanding public expressed concerns about such products as an exposure route for arsenic (e.g. BBC News report, 2017“Should I worry about arsenic in my rice?”) there are few, if any published data on public perceptions of risks associated with exposure to arsenic in rice. We therefore aimed to determine the risk perception of arsenic exposure from rice intake and factors that are associated with arsenic knowledge and whether or not this knowledge had an influence on rice consumption and cooking practices. A questionnaire, targeting participation of rice-eating ethnic minorities in Greater Manchester, UK, was administered to 184 participants. A multivariate generalized linear model was used to determine the factors associated with rice consumption behaviour, cooking practices, and risk perception. We show for the first time that the general population did not associate arsenic, which they perceive as toxic to health, with rice consumption. More than half of the participants knew about arsenic as a hazardous substance but less than ten percent knew that rice consumption could be an important route of arsenic exposure. Knowledge of arsenic was significantly lower in Asian/Asian British:Pakistanis (Pakistani) (OR: 0.006; 95% CI:0.00-0.03) and Asian/Asian British:Bangladeshis (Bangladeshi) (OR: 0.064; 95% CI:0.01-0.25) compared to White:English/Welsh/Scottish/Northern Irish/British (White British). Moreover, Bangladeshis consumed three times more rice (OR: 2.92; 95% CI:1.73-4.93) compared to White British. Overall higher rice consumption was not associated with higher knowledge of the nutritional value of rice. Rinsing rice before cooking, an effective arsenic removal technique, was practised by 93% of the participants, however the most popular cooking method was the use of adequate water (rice to water ratio of 1:2) but not excess water (rice to water ratio of > 1:4), the latter being more effective in removing arsenic. Better education, higher weekly expenditure on food and prior knowledge of arsenic hazard were all significant factors positively influencing a change in behaviour to reduce arsenic exposure from rice intake
Independent optical excitation of distinct neural populations
Optogenetic tools enable examination of how specific cell types contribute to brain circuit functions. A long-standing question is whether it is possible to independently activate two distinct neural populations in mammalian brain tissue. Such a capability would enable the study of how different synapses or pathways interact to encode information in the brain. Here we describe two channelrhodopsins, Chronos and Chrimson, discovered through sequencing and physiological characterization of opsins from over 100 species of alga. Chrimson's excitation spectrum is red shifted by 45 nm relative to previous channelrhodopsins and can enable experiments in which red light is preferred. We show minimal visual system–mediated behavioral interference when using Chrimson in neurobehavioral studies in Drosophila melanogaster. Chronos has faster kinetics than previous channelrhodopsins yet is effectively more light sensitive. Together these two reagents enable two-color activation of neural spiking and downstream synaptic transmission in independent neural populations without detectable cross-talk in mouse brain slice.PostprintPeer reviewe
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