13 research outputs found
Associating polymer-surfactant systems
Some recent illustrations of the phase behavior of polymer-amphiphile systems in solution are presented. Surfactant-polymer association is demonstrated for various amphiphilic synthetic and biological polymers both on a macroscopic and on a single molecular level
Determination of Equilibrium Association Constants of Ligand–DNA Complexes by Electrospray Mass Spectrometry
International audienceElectrospray mass spectrometry can be used to detect ligand-DNA noncovalent complexesformed in solution. This chapter describes how to determine equilibrium associationconstants of the complexes. Particular attention is devoted to describing how to tune anelectrospray mass spectrometer using a 12-mer oligodeoxynucleotides duplex in order toperform these experiments. This protocol can then be applied to any nucleic acid structurethat can be ionized with electrospray mass spectrometry