International Nosocomial Infection Control Consortium report, datasummary of 50 countries for 2010-2015 : Device-associated module

Q3Artículo original1495-1504Background: We report the results of International Nosocomial Infection Control Consortium (INICC) sur-veillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America,Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific.Methods:During the 6-year study period, using Centers for Disease Control and Prevention National Health-care Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregateof 3,506,562 days.Results:Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAIrates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associatedpneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples,frequencies of resistance ofPseudomonasisolates to amikacin (29.87% vs 10%) and to imipenem (44.3%vs 26.1%), and ofKlebsiella pneumoniaeisolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27%vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs.Conclusions:Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported inCDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the re-duction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC’s main goal tocontinue facilitating education, training, and basic and cost-effective tools and resources, such as stan-dardized forms and an online platform, to tackle this problem effectively and systematically

Boletín Clínico, Vol. 04, No.05. Febrero

Revistas recibidas oct. y nov. de 1937 Universidad de Antioquia. Facultad de Medicina. Biblioteca Medica anexo Algunas ideas sobre las ulceras gastroduodenales Yepes Cadavid, Jesús p.193-202 Fabricacion de celulas vivas en los laboratorios Semana medica : Cincuentenario de la academia Academia de Medicina de Medellin p.209 Tratamiento de la tricomoniasis Boletin Clinico p.210 Obstrucion intestinal congenita Mejia Uribe, Rafael p.211-214 Infeccion sin bacterias : El virus y sus efectos en las plantas, en los animales y en el hombre; inmunidad para las celulas vivas; resultado dela investigacion biologica Boletin Clinico p.215-217 El metodo de Hennebert y Leroux para inyecciones intratraqueales p.218-220 La federacion medica y las companias extranjeras Federacion Medica Colombiana p.221 El ministerio de negocios extranjeros de la republica francesa y la universidad de antioquia Movimiento Universitario p.222-227 Un valioso obsequio Universidad de Antioquia. Facultad de Medicina. Biblioteca Medica p.228-229 Coleccion Montoya y Florez adquiridos por compra Universidad de Antioquia. Facultad de Medicina. Biblioteca Medica p.230-237 Reglamento de la primera conferencia nacional de la tuberculosis en Boletin Clinico p.23

Boletín Clínico, Vol. 04, No.04. Enero

Coleccion Francisco A. Uribe Mejia : Libros obsequiados por el Dr. Julio Uribe U. Universidad de Antioquia. Facultad de Medicina. Biblioteca Medica anexo Conferencia sobre constantes urosemiograficas en la altiplanicie y necesidad de la investigación cientifica original Lombana Perez, Joaquin p.147-164 Los medicos colombianos y las compañias extranjeras. Sesion del 20 de diciembre de 1937 Colegio Medico de Antioquia p.165-172 Fracturas del craneo y su tratamiento por la trepanacion Ortiz Velasquez, Julio p. 174-177 Cartilla vitaminicas Boletin Clinico p. 178-184 Los medicos Camargo de Martinez, Leonor p. 185-186 Fiebre artificial Boletin Clinico p.187-189- Una Distincion Bien Merecida p.190-191 Valiosos conceptos acerca de la obra lecciones de botanica del Dr. Emilio Robledo Jaramillo Arango, Roberto ; Montoya T., Wenceslao ; Cadavid Restrepo, Tomas anex

Boletín Clínico, Vol. 04, No.03. Diciembre

Notas bibliograficas * Algunos valiosos conceptos acerca de la obra "Lecciones de Botánica" * Del Doctor Emilio Robledo. * A proposito de un sindromo tifoideo. Pag. 101–112 * Observaciones clinicas un caso raro de ictericia mecanica. Pag. 113–117 * Aplicación de la radiografia en odontologia. Pag.118–121 * Los gallinazos como transmisores de enfermedades. Pag.122–126 * Actividades profesionales. de la academia de medicina de medellin. Pag.127–130 * El caso del Dr. Arciniegas. Pag.131 * Constancia de los médicos de la camara. Pag. 132 * Federación Médica Colombiana. Comité del Colegio Médico de Antioquia * Criminalidad. Pag. 144–149 * Biblioteca de la Facultad de Médicina de la Universidad de Antioquia. * Biblioteca de la Facultad ColecciónFfrancisco A. Uribe MejiaA proposito de un sindromo tifoideo Restrepo, Jose Miguel p.101-112 Observaciones clinicas, un caso raro de ictericia mecanica Velez Toro, Joaquin p.113-117 Aplicación de la radiologia en odontologia Garcia Robledo, Alberto p.118-121 Gallinazos como transmisores de enfermedad Muñoz Rivas, Guillermo p.122-126 Actividades profesionales de la Academia de Medicina De Medellin Academia de Medicina de Medellin p.127-128 Sobre stadium municipal Academia de Medicina de Medellin p.128-130 El caso del Dr. Arciniegas Federacion Medica Colombiana p.131 Constancia de los medicos de la camara Boletin Clinico p.132 Comite del Colegio Medico de Antioquia Federacion Medica Colombiana p.133-143 Criminalidad Academia Nacional de Medicina de Colombia p.14

Evolution of Spinal Cord Transection of Rhesus Monkey Implanted with Polymer Synthesized by Plasma Evaluated by Diffusion Tensor Imaging

In spinal cord injury (SCI) there is damage to the nervous tissue, due to the initial damage and pathophysiological processes that are triggered subsequently. There is no effective therapeutic strategy for motor functional recovery derived from the injury. Several studies have demonstrated neurons growth in cell cultures on polymers synthesized by plasma derived from pyrrole, and the increased recovery of motor function in rats by implanting the polymer in acute states of the SCI in contusion and transection models. In the process of transferring these advances towards humans it is recommended to test in mayor species, such as nonhuman primates, prioritizing the use of non-invasive techniques to evaluate the injury progression with the applied treatments. This work shows the ability of diffusion tensor imaging (DTI) to evaluate the evolution of the SCI in nonhuman primates through the fraction of anisotropy (FA) analysis and the diffusion tensor tractography (DTT) calculus. The injury progression was analysed up to 3 months after the injury day by FA and DTT. The FA recovery and the DTT re-stabilization were observed in the experimental implanted subject with the polymer, in contrast with the non-implanted subject. The parameters derived from DTI are concordant with the histology and the motor functional behaviour

Six-year multicenter study on short-term peripheral venous catheters-related bloodstream infection rates in 727 intensive care units of 268 hospitals in 141 cities of 42 countries of Africa, the Americas, Eastern Mediterranean, Europe, South East Asia, and Western Pacific Regions: International Nosocomial Infection Control Consortium (INICC) findings

Short-term peripheral venous catheter-related bloodstream infection (PVCR-BSI) rates have not been systematically studied in resource-limited countries, and data on their incidence by number of device days are not available. Prospective, surveillance study on PVCR-BSI conducted from September 1, 2013, to May 31, 2019, in 727 intensive care units (ICUs), by members of the International Nosocomial Infection Control Consortium (INICC), from 268 hospitals in 141 cities of 42 countries of Africa, the Americas, Eastern Mediterranean, Europe, South East Asia, and Western Pacific regions. For this research, we applied definition and criteria of the CDC NHSN, methodology of the INICC, and software named INICC Surveillance Online System. We followed 149,609 ICU patients for 731,135 bed days and 743,508 short-term peripheral venous catheter (PVC) days. We identified 1,789 PVCR-BSIs for an overall rate of 2.41 per 1,000 PVC days. Mortality in patients with PVC but without PVCR-BSI was 6.67%, and mortality was 18% in patients with PVC and PVCR-BSI. The length of stay of patients with PVC but without PVCR-BSI was 4.83 days, and the length of stay was 9.85 days in patients with PVC and PVCR-BSI. Among these infections, the microorganism profile showed 58% gram-negative bacteria: Escherichia coli (16%), Klebsiella spp (11%), Pseudomonas aeruginosa (6%), Enterobacter spp (4%), and others (20%) including Serratia marcescens. Staphylococcus aureus were the predominant gram-positive bacteria (12%). PVCR-BSI rates in INICC ICUs were much higher than rates published from industrialized countries. Infection prevention programs must be implemented to reduce the incidence of PVCR-BSIs in resource-limited countries

International Nosocomial Infection Control Consortium (INICC) report, data summary of 45 countries for 2012-2017: Device-associated module

We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2012 to December 2017 in 523 intensive care units (ICUs) in 45 countries from Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. During the 6-year study period, prospective data from 532,483 ICU patients hospitalized in 242 hospitals, for an aggregate of 2,197,304 patient days, were collected through the INICC Surveillance Online System (ISOS). The Centers for Disease Control and Prevention-National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI) were applied. Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the medical-surgical ICUs, the pooled central line-associated bloodstream infection rate was higher (5.05 vs 0.8 per 1,000 central line-days); the ventilator-associated pneumonia rate was also higher (14.1 vs 0.9 per 1,000 ventilator-days,), as well as the rate of catheter-associated urinary tract infection (5.1 vs 1.7 per 1,000 catheter-days). From blood cultures samples, frequencies of resistance, such as of Pseudomonas aeruginosa to piperacillin-tazobactam (33.0% vs 18.3%), were also higher. Despite a significant trend toward the reduction in INICC ICUs, DA-HAI rates are still much higher compared with CDC-NHSN's ICUs representing the developed world. It is INICC's main goal to provide basic and cost-effective resources, through the INICC Surveillance Online System to tackle the burden of DA-HAIs effectively

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically