Mice Liver Microsomes Stabilize Erythrocytes With Respect To Lysis Induced By Trifluoroperazine

[No abstract available]3011671674Seeman, P., (1972) Pharmacol. Rev., 24, pp. 583-655Minetti, M., Di Stasi, A.M.M., (1987) Biochemistry, 26, pp. 8133-8137Yamaguchi, T., Watanabe, S., Kimoto, E., (1985) Biochim. Biophys. Acta, 820, pp. 157-164Vazquez, A., Tudela, J., Varon, E., (1992) Anal. Biochem., 202, pp. 245-248Vazquez, A., Tudela, J., Varon, E., (1992) Biochem. Pharmacol., 44, pp. 889-894Aki, H., Yamamoto, M., (1989) Biochem. Pharmacol., 39, pp. 396-398Omura, T., Sato, R., (1964) J. Biol. Chem., 239, pp. 2371-2385Chargaf, E., (1957) Nucleic Acids, 1, pp. 450-483. , E. Chargaf and J. N. Davidson (eds.), Academis Press, New YorkSeeman, P., (1966) Biochem. Pharmacol., 15, pp. 1737-1752Pereira, R.S., Bertocci, A.P.F., Vercesi, A.E., (1992) Biochem. Pharmacol., 41, pp. 1-

Metabolic Oxidation Of Dipyridamole(dip) By Mouse Liver Microsomes

A method of spectrofluorimetric monitoring of dipyridamole (DIP) metabolism has been developed. The spectrophotometric monitoring of NADPH microsomal oxidation as a measure of DIP metabolism has also been performed. The drug metabolic oxidation by microsomes requires NADPH and is accompanied by the oxidation of both cofactor and cytochrome b5. Carbon monoxide inhibits DIP metabolic oxidation.211120126Mancuso, G., (1995) Genitourinary Medicine, 71, p. 57Selley, M.L., (1994) Atherosclerosis, 111, p. 91Pospisil, M., (1995) Rad. Res., 142, p. 16Snoek, R., (1994) Antiviral Chemistry & Chemotherapy, 5, p. 312Sato, S., (1993) Anti-cancer Drug Design, 8, p. 289Damile, B.D., (1994) Int J. Cancer, 56, p. 113Vallejo, C.T., (1995) Amer. J. Clin. Oncol., 18, p. 185Ragazzi, E., (1995) Int. J. Oncol., 6, p. 659Iuliano, L., (1992) Lipids, 27, p. 349Lowry, O.H., (1951) Biol Chem., 193, p. 265Omura, T., Sato, R., (1964) J. Biol. Chem., 239, p. 2371Degterev, I.A., (1990) Pharmac. Chem. J., 24, p. 9Verovskiy, V.N., (1990) Pharmac. Chem. J., 24, p. 20Degterev, I.A., (1993) Bioactive Compounds. Biotransformation and Biological Action, , NOVA Science Publ., New Yor