Application of chemometric analysis to infrared spectroscopy for the identification of wood origin

Chemical characteristics of wood are used in this study for plant taxonomy classification based on the current Angiosperm Phylogeny Group classification (APG III System) for the division, class and subclass of woody plants. Infrared spectra contain information about the molecular structure and intermolecular interactions among the components in wood but the understanding of this information requires multivariate techniques for the analysis of highly dense datasets. This article is written with the purposes of specifying the chemical differences among taxonomic groups, and predicting the taxa of unknown samples with a mathematical model. Principal component analysis, t-test, stepwise discriminant analysis and linear discriminant analysis, were some of the chosen multivariate techniques. A procedure to determine the division, class, subclass and order of unknown samples was built with promising implications for future applications of Fourier Transform Infrared spectroscopy in wood taxonomy classification

Pedro Madruga : leyenda

Convenio RA

Cistectomía parcial laparoendoscópica umbilical

The aim of this study is to present our center's experience in single-port umbilical laparoendoscopic partial cystectomies, in both benign and malignant pathologies. Patient characteristics, perioperative aspects and the surgical techniques used are reviewed. Since May 2012, five patients have undergone a transumbilical single-port laparoendoscopic partial cystectomy with curved equipment through a reusable multichannel system and a 3.5 mm accessory trocar. Patients were three males and two females aged between 28 and 78 (median: 44 ± 42.5) years. The etiologies were endometriosis (in 2 cases), a tumor in the diverticulum, a congenital bladder diverticulum and ureterocele (1 case of each).0.964 JCR (2015) Q4, 63/77 Urology & nephrologyUE

Eficacia de la terapia de ondas de choque de baja intensidad para la disfunción eréctil: revisión sistemática y metaanálisis

Context The low-intensity shockwave (LISW) therapy is a recently developed modality for treating erectile dysfunction. Objective To assess the efficacy of LISW therapy for treating erectile dysfunction as described in the literature. Acquisition of evidence Two independent reviewers identified studies eligible for a systematic review and meta-analysis of various sources written in English and Spanish, using the databases of PubMed, EMBASE and Web of Science. We excluded studies on Peyronie's disease. We employed the DerSimonian-Laird method for defining heterogeneity, calculating the grouped standard deviation of the mean (SDM). The primary objective of this review is to assess efficacy based on the change in the International Index of Erectile Function (IIEF-EF) over baseline at 1 month from the start of treatment, both for the treatment arm and the placebo arm. The secondary objective is focused on analysing IIEF-EF at 3–6 months from the start of the therapy. Summary of the evidence The pooled data of 636 patients from 12 studies showed that treatment with LISW resulted in a significant increase in IIEF-EF at 1 month with respect to baseline (SDM, −2.92; p = 0.000), to a greater degree than placebo (SDM, −0.99; p = 0.000). The IIEF-EF at 3–6 months for the treated patients was significantly greater than baseline (SDM, −2.78; p = 0.000). Only one study compared the efficacy of placebo at 3–6 months vs baseline (SDM, −9.14). The comparison between LISW and placebo favors active treatment (SDM, 2.53; p = 0.000) at 1 month. There are insufficient data in the literature to assess the response over placebo at 3–6 months. Conclusions According to the literature, treatment with LISW for erectile dysfunction is effective, both in the short and medium term. LISW has been described as more effective than placebo in the short term. The long-term efficacy data are insufficient. More studies are needed to explain the role of this therapy according to specific causes of erectile dysfunction.Contexto La terapia con ondas de choque de baja intensidad (OCBI) es una modalidad de reciente uso en el tratamiento de la disfunción eréctil. Objetivo Evaluar la eficacia de la terapia con OCBI para el tratamiento de la disfunción eréctil según se describe en la literatura. Adquisición de evidencia Dos revisores independientes identificaron estudios elegibles para llevar a cabo revisión sistemática y metaanálisis de diferentes fuentes escritas en inglés y español, utilizando las bases de datos de PubMed, Embase y Web of Science. Se excluyeron los estudios sobre la enfermedad de Peyronie. Se utilizó el método Der Simonian-Laird para definir la heterogeneidad calculando la desviación estándar de la media (DME) agrupada. El objetivo primario de esta revisión es evaluar la eficacia según el cambio del Índice internacional de función eréctil (IIEF-EF) sobre basal al mes de inicio de tratamiento, tanto para el brazo de tratamiento como para el brazo placebo. El objetivo secundario se centra en analizar IIEF-EF a 3-6 meses tras el inicio de la terapia. Síntesis de evidencia Los datos agrupados de 636 pacientes procedentes de 12 estudios mostraron que el tratamiento con OCBI conlleva un aumento significativo de IIEF-EF al mes con respecto a basal (DME = –2,92; p = 0,000), en un grado mayor que placebo (DME = –0,99; p = 0,000). El IIEF-EF a 3-6 meses en pacientes tratados fue significativamente mayor que basal (DME = –2,78; p = 0,000). Solo hay un estudio que compara eficacia de placebo a 3-6 meses vs basal (DME = –9,14). La comparación entre OCBI y placebo favorece el tratamiento activo (DME = 2,53; p = 0,000) al mes. No existen datos suficientes para evaluar respuesta sobre placebo a los 3-6 meses en la literatura. Conclusiones El tratamiento con OCBI para la disfunción eréctil según la literatura resulta eficaz, tanto a corto como a medio plazo. A corto plazo se ha descrito incluso más eficaz que placebo. Los datos sobre eficacia a largo plazo son insuficientes. También se necesitan más estudios para dilucidar el papel de esta terapia según las causas específicas de la disfunción eréctil.Sin financiación1.260 JCR (2017) Q4, 61/76 Urology and NephrologyUE

Treatment for long bulbar urethral strictures with membranous involvement using urethroplasty with oral mucosa graft

Estudio prospectivo sobre 14 pacientes con estenosis de uretra bulbomembranosa sometidos a uretroplastia de ampliación con injerto de mucosa bucal entre 2005 y 2013, según la técnica de Barbagli modificada con anclaje proximal del injerto y fijación del mismo sobre la albugínea cavernosa en 12 casos (%) y ventralmente en 2 (%). El tiempo de seguimiento mínimo fue de un año. Se evaluaron resultados subjetivos (satisfacción del paciente) y objetivos (Qmáx y RPM pre y postoperatorios) y complicaciones. Se consideró fracaso la necesidad de cualquier instrumentación postoperatoria.1.022 JCR (2014) Q4, 60/76 Urology & nephrologyUE

Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia

This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer’s disease are also present during the disorder’s preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating between those older people with MCI and a high probability of developing dementia and those with MCI that will not do so. We found that the disease’s most differentiating parameters prior to its onset involve changes in speech duration and an alteration in rhythm rate and intensity. These parameters seem to be related to the first difficulties in lexical access among older people with AD

Two-port laparoscopic reconstructive surgery of the urinary tract with reusable umbilical system (hybrid less): a proof of concept study

Objectives: We compared perioperative results and complications of reconstructive surgery of the urinary tract performed using a multichannel platform through the umbilicus and one additional 3.5-mm with a cohort of patients simultaneously treated with conventional 4-port laparoscopy. Materials and methods: Matched-pair study comparing perioperative outcomes, postoperative visual analogue pain scale (VAPS) and morbidity of 2-port (n = 20) and 4-port (n = 10) laparoscopic reconstructive urological surgery. Preoperative and perioperative data compared included demographics, type of surgery, operative time, blood loss, decrease in serum hemoglobin, operative complications, length of stay and postoperative complications according to Clavien-Dindo classification. Results: There was no significant difference between groups regarding age, gender, body mass index, American Society of Anesthesiologists score, type of surgery, operative time, operative complications and intraoperative or postoperative transfusion. Estimated blood loss was lower using reduced-port approach. VAPS at postoperative day one was significantly lower for 2-port approach and so was the length of stay. Patient satisfaction with the wound was higher for 2-port surgery. Differences were not observed in number and severity of postoperative complications. Conclusions: Urological reconstructive operations can be safely performed using the hybrid laparoendoscopic single-site umbilical approach, resulting in lower blood loss, higher patient satisfaction and lower postoperative pain, which also facilitate earlier hospital discharge, than the same reconstructive procedures performed through multiport conventional laparoscopy.Sin financiación1.611 JCR (2016) Q3, 49/77 Urology & NephrologyUE

Comparative study of hybrid laparoendoscopic single-site (LESS) partial nephrectomy and conventional multiport laparoscopy

Objetivo: Comparar resultados operatorios y oncológicos de la nefrectomía parcial realizada mediante abordaje laparoendoscópico a través de puerto único (LESS) reutilizable y laparoscópico multipuerto. Material y método: Estudio comparativo prospectivo pareado no aleatorizado de pacientes tratados con nefrectomía parcial mediante abordaje LESS híbrido con trocar auxiliar de 3,5 mm (n = 20) y con laparoscopia multipuerto convencional (n = 26). Resultados: La media de seguimiento fue 31 ± 18,6 meses. Un caso LESS (5%) se reconvirtió a laparoscopia. No hubo diferencias significativas entre grupos con respecto a edad, sexo, índice de masa corporal, lateralidad, localización, tamaño tumoral o empleo de doble-J; aunque hubo dominancia de ASA-I (p = 0,09) y de histología benigna (p = 0,05) en el grupo LESS. Tampoco hubo diferencias en tiempo operatorio, tiempo de isquemia, empleo de materiales hemostáticos, sangrado estimado, hemoglobina postoperatoria, transfusión u otras complicaciones. Ningún caso precisó ampliar herida cutánea para extracción de espécimen. Los pacientes LESS tuvieron menor tiempo de drenaje (p = 0,006) y menor estancia hospitalaria (p = 0,003). No hubo diferencias en número ni severidad de complicaciones según escala Clavien-Dindo. Un paciente en grupo laparoscópico falleció por TEP tras el alta hospitalaria. No hubo márgenes positivos ni recidivas o progresión de la enfermedad tumoral en el tiempo evaluado. Conclusiones: La nefrectomía parcial LESS no implica ventajas en resultados operatorios salvo menor estancia hospitalaria, posiblemente debido a hemostasia operatoria más precisa y/o selección de casos. No conlleva riesgos operatorios y oncológicos, pero tampoco supone mejora en tiempo de isquemia, pérdida hemática o tasa de transfusión. Tampoco supone una ventaja evidente en términos cosméticos.Objective: To investigate the surgical and oncological outcomes of hybrid laparoendoscopic single-site (LESS) in partial nephrectomy with reusable components compared with multiport laparoscopy. Material and method: Hybrid LESS technique with auxiliary 3.5 mm trocar (n = 20) was compared with conventional multiport laparoscopy (n = 26) by a prospective, paired, nonrandomized, and comparative study in partially nephrectomized patients. Results: Follow-up average was 31 ± 18.6 months. In one case, LESS was converted to laparoscopy. No differences were found regarding age, sex, body mass index, laterality, localization, tumor size or use of double J stent. Dominance of Loop-I (P = 0.09) and benign histology (P = 0.05) were observed in the LESS group. Neither there were differences regarding operating time, ischemia time, use of hemostatic materials, estimated blood loss, postoperative hemoglobin levels, transfusion or other complications. In any case, to extend the skin incision for specimen extraction was not necessary. Drainage time (P = 0.006) and hospital stay (P = 0.003) were better in LESS patients. Concerning complications, no significant differences were observed according Clavien-Dindo scale. In laparoscopic group one patient died of pulmonary embolism after hospital discharge. No positive margins were observed in any case. During follow-up neither tumor recurrence nor disease progression were observed. Conclusions: Regarding surgical outcomes, partial nephrectomy by LESS technique does not imply improvements, excepting shorter hospital stay, probably due to accurate surgical hemostasis and/or selection of cases. No surgical and oncological risks are involved, as well as no improvement in ischemia time, blood loss or transfusion rate. We find no significant difference in cosmetic outcomes.Sin financiación1.260 JCR (2017) Q4, 61/76 Urology and NephrologyUE