4 research outputs found
Investigations on Hepatoprotective Activity of Leaf Extracts of Aegle marmelos (L.) Corr. (Rutaceae)
The present study was carried out to screen and evaluate the hepatoprotective activity of leaf extracts of Aegle marmelos (L.) Corr. Hepatoprotective activities of ethanolic and aqueous extracts of A. marmelos were examined against carbon tetrachloride induced liver damage in mice using silymarin as control. Enzyme activities of Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT) and Alkaline Phosphatase (ALP) were analyzed. Results indicate that ethanolic and aqueous leaf extracts of A. marmelos had moderate activity over carbon tetrachloride treatment as compared to control. Results of the present investigation confirm the traditional uses of this plant as a potential hepatoprotective agent
Studies on Hepatoprotective Properties of Leaf Extracts of Azadirachta indica A. Juss (Meliaceae)
The present study was carried out to evaluate the hepatoprotective role of leaf extracts of Azadirachta indica A. Juss. Hepatoprotective activities of ethanolic and aqueous extracts of A. indica were examined against carbon tetrachloride induced liver damage in mice using silymarin as control. Enzyme activities of Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT) and Alkaline Phosphatase (ALP) were analyzed. Phytochemical leaf extracts of A. indica exhibited significant hepatoprotective activity. Ethanolic and aqueous leaf extracts of A. indica exhibited moderate activity over carbon tetrachloride treated animals. Results confirm the traditional - ethnomedicinal use of A. indica as a potential source of hepatoprotective agent
Antioxidant activity of Arthritin-A polyherbal formulation
403-407In complete
freund’s adjuvant induced arthritis in male albino rats, a significant increase
in serum lipid peroxidase besides increase in paw swelling and a significant
decrease in superoxide dismutase, glutathione peroxidase and total reduced
glutathione levels were observed. Arthritin produced a marked reversal of these
enzyme levels, besides a significant reduction in paw swelling. The results
suggest that, the polyherbal formulation ‘Arthritin’ exerts its effects by
modulating lipid peroxidation and enhancing anti-oxidant and detoxifying enzyme
systems