8,849 research outputs found
Coherent control of collective nuclear quantum states via transient magnons
Ultrafast and precise control of quantum systems at x-ray energies involves photons with oscillation periods below 1 as. Coherent dynamic control of quantum systems at these energies is one of the major challenges in hard x-ray quantum optics. Here, we demonstrate that the phase of a quantum system embedded in a solid can be coherently controlled via a quasi-particle with subattosecond accuracy. In particular, we tune the quantum phase of a collectively excited nuclear state via transient magnons with a precision of 1 zs and a timing stability below 50 ys. These small temporal shifts are monitored interferometrically via quantum beats between different hyperfine-split levels. The experiment demonstrates zeptosecond interferometry and shows that transient quasi-particles enable accurate control of quantum systems embedded in condensed matter environments
Spatially resolved spectroscopy of monolayer graphene on SiO2
We have carried out scanning tunneling spectroscopy measurements on
exfoliated monolayer graphene on SiO to probe the correlation between its
electronic and structural properties. Maps of the local density of states are
characterized by electron and hole puddles that arise due to long range
intravalley scattering from intrinsic ripples in graphene and random charged
impurities. At low energy, we observe short range intervalley scattering which
we attribute to lattice defects. Our results demonstrate that the electronic
properties of graphene are influenced by intrinsic ripples, defects and the
underlying SiO substrate.Comment: 6 pages, 7 figures, extended versio
Ability of FFR-CT to detect the absence of hemodynamically significant lesions in patients with high-risk NSTE-ACS admitted in the emergency department with chest pain, study design and rationale.
In the era of High-sensitive troponin (hs-Tn), up to 50% of patients with a mild increase of hs-Tn will finally have a normal invasive coronary angiogram. Fractional Flow Reserve (FFR) derived from coronary computed tomographic angiography (FFR-CT) has never been used as a non-invasive tool for the diagnosis of coronary artery disease in patients with high-risk acute coronary syndrome without ST segment elevation (NSTE-ACS).
The study aims to determine the role of coronary CT angiography and FFR-CT in the setting of high-risk NSTE-ACS.
We will conduct a prospective trial, enrolling 250 patients admitted with high-risk NSTE-ACS who will rapidly undergo a coronary CT angiography and then a coronary angiography with FFR measurements. Results of coronary CT, FFR-CT and coronary angiography (± FFR) will be compared.
In conclusion, non-invasive identification of patients with high-risk NSTE-ACS who could avoid coronary angiography would reduce procedure related risks and medical costs
Charge-induced conformational changes of dendrimers
We study the effect of chargeable monomers on the conformation of dendrimers
of low generation by computer simulations, employing bare Coulomb interactions.
The presence of the latter leads to an increase in size of the dendrimer due to
a combined effect of electrostatic repulsion and the presence of counterions
within the dendrimer, and also enhances a shell-like structure for the monomers
of different generations. In the resulting structures the bond-length between
monomers, especially near the center, will increase to facilitate a more
effective usage of space in the outer-regions of the dendrimer.Comment: 7 pages, 12 figure
Quantum computing with antiferromagnetic spin clusters
We show that a wide range of spin clusters with antiferromagnetic
intracluster exchange interaction allows one to define a qubit. For these spin
cluster qubits, initialization, quantum gate operation, and readout are
possible using the same techniques as for single spins. Quantum gate operation
for the spin cluster qubit does not require control over the intracluster
exchange interaction. Electric and magnetic fields necessary to effect quantum
gates need only be controlled on the length scale of the spin cluster rather
than the scale for a single spin. Here, we calculate the energy gap separating
the logical qubit states from the next excited state and the matrix elements
which determine quantum gate operation times. We discuss spin cluster qubits
formed by one- and two-dimensional arrays of s=1/2 spins as well as clusters
formed by spins s>1/2. We illustrate the advantages of spin cluster qubits for
various suggested implementations of spin qubits and analyze the scaling of
decoherence time with spin cluster size.Comment: 15 pages, 7 figures; minor change
The Magnetorotational Instability in Core Collapse Supernova Explosions
We investigate the action of the magnetorotational instability (MRI) in the
context of iron-core collapse. Exponential growth of the field on the rotation
time scale by the MRI will dominate the linear growth process of field line
"wrapping" with the same characteristic time. We examine a variety of initial
rotation states, with solid body rotation or a gradient in rotational velocity,
that correspond to models in the literature. A relatively modest value of the
initial rotation, a period of ~ 10 s, will give a very rapidly rotating PNS and
hence strong differential rotation with respect to the infalling matter. We
assume conservation of angular momentum on spherical shells. Results are
discussed for two examples of saturation fields, a fiducial field that
corresponds to Alfven velocity = rotational velocity and a field that
corresponds to the maximum growing mode of the MRI. Modest initial rotation
velocities of the iron core result in sub-Keplerian rotation and a
sub-equipartition magnetic field that nevertheless produce substantial MHD
luminosity and hoop stresses: saturation fields of order 10^{15} - 10^{16} G
develop within 300 msec after bounce with an associated MHD luminosity of about
10^{52} erg/s. Bi-polar flows driven by this MHD power can affect or even cause
the explosions associated with core-collapse supernovae.Comment: 42 pages, including 15 figures. Accepted for publication in ApJ. We
have revised to include an improved treatment of the convection, and some
figures have been update
Transcaval versus Supra-Aortic Vascular Accesses for Transcatheter Aortic Valve Replacement: A Systematic Review with Meta-Analysis.
A growing body of evidence suggests that extrathoracic vascular accesses for transcatheter aortic valve replacement (TAVR) yield favorable outcomes and can be considered as primary alternatives when the gold-standard transfemoral access is contraindicated. Data comparing the transcaval (TCv) to supra-aortic (SAo) approaches (transcarotid, transsubclavian, and transaxillary) for TAVR are lacking. We aimed to compare the outcomes and safety of TCv and SAo accesses for TAVR as alternatives to transfemoral TAVR. A systematic review with meta-analysis was performed by searching PubMed/MEDLINE and EMBASE databases for all articles comparing TCv-TAVR against SAo-TAVR published until September 2023. Outcomes included in-hospital or 30-day all-cause mortality (ACM) and postoperative complications. A total of three studies with 318 TCv-TAVR and 179 SAo-TAVR patients were included. No statistically significant difference was found regarding in-hospital or 30-day ACM (relative risk [RR] 1.04, 95% confidence interval [CI] 0.47-2.34, p = 0.91), major bleeding, the need for blood transfusions, major vascular complications, and acute kidney injury. TCv-TAVR was associated with a non-statistically significant lower rate of neurovascular complications (RR 0.39, 95%CI 0.14-1.09, p = 0.07). These results suggest that both approaches may be considered as first-line alternatives to transfemoral TAVR, depending on local expertise and patients' anatomy. Additional data from long-term cohort studies are needed
Polarization state of the optical near-field
The polarization state of the optical electromagnetic field lying several
nanometers above complex dielectric structures reveals the intricate
light-matter interaction that occurs in this near-field zone. This information
can only be extracted from an analysis of the polarization state of the
detected light in the near-field. These polarization states can be calculated
by different numerical methods well-suited to near--field optics. In this
paper, we apply two different techniques (Localized Green Function Method and
Differential Theory of Gratings) to separate each polarisation component
associated with both electric and magnetic optical near-fields produced by
nanometer sized objects. The analysis is carried out in two stages: in the
first stage, we use a simple dipolar model to achieve insight into the physical
origin of the near-field polarization state. In the second stage, we calculate
accurate numerical field maps, simulating experimental near-field light
detection, to supplement the data produced by analytical models. We conclude
this study by demonstrating the role played by the near-field polarization in
the formation of the local density of states.Comment: 9 pages, 11 figures, accepted for publication in Phys. Rev.
The Impact II, a Very High-Resolution Quadrupole Time-of-Flight Instrument (QTOF) for Deep Shotgun Proteomics
Hybrid quadrupole time-of-flight (QTOF) mass spectrometry is one of the two major principles used in proteomics. Although based on simple fundamentals, it has over the last decades greatly evolved in terms of achievable resolution, mass accuracy, and dynamic range. The Bruker impact platform of QTOF instruments takes advantage of these developments and here we develop and evaluate the impact II for shotgun proteomics applications. Adaption of our heated liquid chromatography system achieved very narrow peptide elution peaks. The impact II is equipped with a new collision cell with both axial and radial ion ejection, more than doubling ion extraction at high tandem MS frequencies. The new reflectron and detector improve resolving power compared with the previous model up to 80%, i.e. to 40,000 at m/z 1222. We analyzed the ion current from the inlet capillary and found very high transmission (>80%) up to the collision cell. Simulation and measurement indicated 60% transfer into the flight tube. We adapted MaxQuant for QTOF data, improving absolute average mass deviations to better than 1.45 ppm. More than 4800 proteins can be identified in a single run of HeLa digest in a 90 min gradient. The workflow achieved high technical reproducibility (R2 > 0.99) and accurate fold change determination in spike-in experiments in complex mixtures. Using label-free quantification we rapidly quantified haploid against diploid yeast and characterized overall proteome differences in mouse cell lines originating from different tissues. Finally, after high pH reversed-phase fractionation we identified 9515 proteins in a triplicate measurement of HeLa peptide mixture and 11,257 proteins in single measurements of cerebellum-the highest proteome coverage reported with a QTOF instrument so far
Magnetization steps in a diluted Heisenberg antiferromagnetic chain: Theory and experiments on TMMC:Cd
A theory for the equilibrium low-temperature magnetization M of a diluted
Heisenberg antiferromagnetic chain is presented. The magnetization curve, M
versus B, is calculated using the exact contributions of finite chains with 1
to 5 spins, and the "rise and ramp approximation" for longer chains. Some
non-equilibrium effects that occur in a rapidly changing B, are also
considered. Specific non-equilibrium models based on earlier treatments of the
phonon bottleneck, and of spin flips associated with cross relaxation and with
level crossings, are discussed. Magnetization data on powders of TMMC diluted
with cadmium [i.e., (CH_3)_4NMn_xCd_(1-x)Cl_3, with 0.16<=x<=0.50 were measured
at 0.55 K in 18 T superconducting magnets. The field B_1 at the first MST from
pairs is used to determine the NN exchange constant, J, which changes from -5.9
K to -6.5 K as x increases from 0.16 to 0.50. The magnetization curves obtained
in the superconducting magnets are compared with simulations based on the
equilibrium theory. Data for the differential susceptibility, dM/dB, were taken
in pulsed magnetic fields (7.4 ms duration) up to 50 T, with the powder samples
in a 1.5 K liquid-helium bath. Non-equilibrium effects, which became more
severe as x decreased, were observed. The non-equilibrium effects are
tentatively interpreted using the "Inadequate Heat Flow Scenario," or to
cross-relaxation, and crossings of energy levels, including those of excited
states.Comment: 16 pages, 14 figure
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