Economic Analysis of Tradeoffs Between Security and Disaster Recovery

The threat of computer crime is increasingly becoming a big concern for organizations. Organizations have to continuously manage their investment in information security technologies in an attempt to minimize the damage caused by information resource breaches. This article proposes an economic model in an attempt to evaluate the trade-offs between security and disaster-recovery technologies. The article intends to provide a directional strategy for managers in terms of increasing budgetary allocations for each of these technologies. The proposed model presents insights for managers

Is More Information Better? The Effect of Traders\u27 Irrational Behavior on an Artificial Stock Market

This paper presents a computer simulated artificial stock market to examine market rationality issues. We constructeconomicagentswithdifferentdegreesofirrationalitytoparticipateinthestockmarket. Theagents replicate the irrational behaviors described in the psychology and finance literatures and determine the outcome of the market. The main focus of this study is to examine the two contradicting (efficient market versus noise trading) finance hypotheses in the presence of rational and irrational traders

The Experimental Analysis of Information Security Management Issues for Online Financial Services

E-commerce offers the banking industry great opportunity, but also creates a set of new risks and vulnerability such as security threats. Information security, therefore, is an essential management and technical requirement for any efficient and effective financial activities over the Internet. Still, its definition is a complex endeavor due to the constant technological and business change and requires a coordinated match of managerial and technical solutions. This research intends to provide an instrument to test and evaluate the strategies to counter threats facing online financial institutions through an artificial economic setup at the Synthetic Environments for Simulation and Analysis (SEAS) laboratory at the Krannert Graduate School of Management, Purdue University. The research also intends to provide guidelines for forming information security policies and strategies for survival and success in the dynamic and hostile business environment. Initial results indicate that online banks that were proactive in recognizing the threats and devising policies to counter them generated greater revenue and were able to focus on the core activities. Public disclosure of security breaches by the victim banks resulted in better overall health of the simulated economy. The simulation is still in its development and testing phase and the research team intends to present the findings at the conference

Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma

A sensitive and specific high performance reversed phase liquid chromatographic method was developed for quantification of citicoline monosodium (CTM) in human plasma. The active drug was isocratically eluted at a flow rate of 1 ml/min at ambient temperature in a nucleosil C18 analytical column with a mobile phase composed of tetrabutyl ammonium hydro gen sulfate buffer (0.005 M, pH5.0): methanol (95:05, v/v). Photodiode array (PDA) was performed at 270 nm and the retention time of the drug was found to be 6.64 min. The lowest limit of quantification (LLOQ) and of detection (LOD) were found to be 30 and 10 ng/ml, respectively. The method was validated and the response was found to be linear in the drug (CTM in spiked plasma) concentration range 150-900 ng/ml. The method was found to be accurate, with ranging from 96.38 to 98.65 % and precise, with intra-day, inter-day as well as analyst-toanalyst precision. The total recoveries of the method ranged between 95.69 and 97.89 %. Stability data revealed that the drug is stable in human plasma under various test conditions and the method can be successfully used for analysis of CTM in human plasma and in pharmacokinetic studies.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Impact of COVID-19 on tourism in Nepal

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Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Quality of Education, Productivity Changes, and Income Distribution.

A general equilibrium model of a dual economy is constructed with workers and managers and hierarchical production. Ability is continuous, and there is perfect competition in the product market. Higher quality of education is treated as a form of technical progress. An equilibrium wage profile is derived. Different kinds of technical and productivity changes yield different gainers and losers. Declines in the quality of education generally lead to an increase in inequality. Surprisingly, groups suffering from declines in quality of education often benefit at the costs of others. Parallels are drawn with recent experience. Copyright 2000 by University of Chicago Press.