Unilateral Vision Loss without Ophthalmoplegia as a Rare Complication of Spinal Surgery

Postoperative visual loss is an extremely rare complication of nonocular surgery. The most common causes are ischemic optic neuropathy, central retinal artery occlusion, and cerebral ischemia. Acute visual loss after spinal surgery is even rarer. The most important risk factors are long-lasting operations, massive bleedings, fluid overload, hypotension, hypothermia, coagulation disorders, direct trauma, embolism, long-term external ocular pressure, and anemia. Here, we present a case of a 54-year-old male who developed acute visual loss in his left eye after a lumbar instrumentation surgery and was diagnosed with retinal artery occlusion

Konya‘da nadir görülen zoonotik infeksiyon; babesiozis olgu sunumu

Babesiozis, Babesia mikroorganizmasının sebep olduğu eritrosit içi kene kaynaklı zoonotik bir infeksiyondur. Ülkemizde sporadik olarak görülmekle birlikte insan babesiozisi konusunda yayınlanmış çok fazla olgu bulunmamaktadır. Bu olguda ateş, pansitopeni nedeniyle araştırılan, kene teması olmadığı halde perifer kan yaymasında eritrosit içi parazitler görülerek, Babesiozis tanısı ile kinin ve klindamisin ile tedavi edilmiş ve tedavinin ikinci gününde ateşi düşüp tam kan sayımı düzelen bir olgu sunuyoruz

Analysis of peripapillary choroidal thickness in unilateral amblyopia

Purpose: To evaluate the peripapillary choroidal thickness (CT) in children with unilateral amblyopia using spectral-domain optical coherence tomography (SD-OCT). Methods: One hundred and six eyes of 53 children with unilateral amblyopia and 20 eyes of 20 children with normal vision were involved in this study. Of the 53 children with unilateral amblyopia, 29 (54.7%) had hyperopic anisometropic amblyopia and 24 (45.3%) had strabismic amblyopia. Peripapillary CT was measured from 6 mm length radial B-scans at the optic nerve head using the enhanced depth imaging program of an SD-OCT (Heidelberg Engineering, Germany). Age, sex, refractive error, and best-corrected visual acuity were also recorded. Results: The average peripapillary CT was greater in amblyopic eyes than in the fellow eyes of the children with amblyopia (P = 0.002), and control eyes (P < 0.001). There was no significant difference between the fellow eyes of children with amblyopia and the control eyes (P = 0.158). The average peripapillary CT was negatively correlated with axial length (AL) in amblyopic eyes (r = -0.381; P = 0.005) and fellow eyes (r = -0.392; P = 0.004) but not in control eyes (r = -0.232; P = 0.325). After adjustment for the possible effects of AL, the average peripapillary CT in amblyopic eyes was still greater than in fellow eyes (P = 0.014) and control eyes (P = 0.022). Conclusion: The peripapillary choroid of eyes with amblyopia was thicker than that of the fellow eyes and control eyes. No significant difference was observed between fellow eyes and control eyes

Shigella flexneri Bacteremia in a Patient with Behcet’s Disease and Receiving Immunosuppressive Treatment: A Case Report

Shigella bacteremia usually causes gastrointestinal infections and has a table of disease accompanied by abdominal pain, bloody diarrhoea and fever. Bacteremia is not a common case but develops in the children under two years age and in malnourished children. Shigella bacteremia has a high rate of mortality and is a rare complication in adults which usually occurs in the presence of predisposing factors as diabetes and steroid use. In this study we presented a case, who had Behçet’s disease and received immunosuppressive treatment, developed S. flexneri bacteremia at the age of 56

A case-control study on the temperament and Psychological mood of patients with chronic Hepatitis B

WOS: 000419796200001Objective: To evaluate the personality and temperament traits in patients with chronic hepatitis B in comparison to healthy subjects and to determine whether there is a relation between personality trait and level of anxiety or depression. Materials/Subjects and Method: This was a case-control study in which 67 patients who had been under follow-up with diagnosis of chronic hepatitis B and 103 aged-matched healthy subjects were included. Study participants were asked to complete three self-report questionnaires-Temperament and Character Inventory (TCI) to define personality traits, Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) to evaluate presence and severity of depression and anxiety. Results: Total and sub-scale scores of five out of seven dimensions of TCI-reward dependence, persistence, self-directedness, cooperativeness, and self-transcencewere significantly higher in Group 1 than Group 2. Total BDI and BAI scores were significantly higher in Group 1 than Group 2. Significantly more patients had a BDI score of 17 or over in Group 1 than Group 2. There was no significant correlation between total scores of TCI dimensions and total BAI or BDI scores except weak correlations between harm avoidance or self-directedness and total BAI or BDI scores. Conclusion: In terms of personality trait, patients with chronic hepatitis B exhibit higher reward dependence, persistence, self-directedness, cooperativeness, and self-transcendence from healthy population. The personality traits of patients should be considered during the management of hepatitis B in order to optimize treatment outcome and to prevent development of new mental health problems during the course of the disease

Association of Tumor Necrosis Factor Alpha -238G/A and -308G/A Promotor Polymorphisms with Clearance of Hepatitis B Virus Infection in Turkish Population

Objectives: Acute viral hepatitis B may lead to chronic hepatitis in 6% of adultpopulation. We compared the frequency of Tumor necrosis factor alpha promotor polymorphisms in chronic hepatitis B patients and people with natural immunity against hepatitis B.Materials and Methods: Chronic hepatitis B patients and age matched control cases with natural immunity to hepatitis B virus were recruited 1:1 in this study. Tumornecrosis factor alpha -238G/A and -308G/A polymorphisms were studied withPCR-RFLP. ?2 test was performed in statistical analysis.Results: A total of 101 volunteers enrolled in two study groups. Thirty-eight menand 12 women constituted the chronic hepatitis B patient group and 40 men and11 women recruited in natural immunity group. Frequency of -238G allele was87.5% and 97% in chronic hepatitis B and natural immunity groups, respectively.Frequency of -308G allel was 93% and 92.1% in chronic hepatitis B and natural im-munity groups, respectively. Frequencies of polymorphisms at positions -238 and-308 in the promotor of tumor necrosis factor alpha gene were not different be-tween chronic hepatitis B and natural immunity groups.Discussion: Tumor necrosis factor alpha promoter polymorphisms at -238 and-308 positions do not effect the outcome hepatitis B infection in Turkish population. Clearance of hepatitis B virus infection is multifactorial. Thus, further studiesneeded to identify genetic predisposition to chronic hepatitis B infection

Transscleral diode laser cyclophotocoagulation in refractory glaucoma

Amaç: Medikal veya cerrahi tedavilerle kontrol edilemeyen ileri evre glokom olgularında transskleral diod lazer siklofotokoagülasyon (TSDLS) uygulamasının güvenilirliğinin ve etkinliğinin değerlendirilmesi. Gereç ve Yöntem: 2009-2011 yılları arasında TSDLS tedavisi uygulanan olgular retrospektif olarak incelendi. Tedavi öncesi ve sonrası göz içi basıncı (GİB) değerleri, görme keskinlikleri, kullanılan antiglokomatöz tedavi sayıları ve komplikasyonlar kaydedildi. TSDLS başarı kriteri, son kontrolde GİB ölçümünün 6-22 mmHg (ilaçlı ya da ilaçsız) olması olarak belirlendi. Sonuçlar: Çalışmaya 37 olgunun 37 gözü dahil edildi. Olguların yaş ortalaması 61,7317,13 yıl (19-80 yıl) ve ortalama takip süresi 8,065,81 ay (3-22 ay) idi. Tedavi öncesi ortalama GİB değerleri 38,688,94 mmHg, tedavi sonrası 2. haftada 26,4611,34 mmHg (p 0,01) ve son kontrolde 24,9710,84 mmHg (p0,01) idi. Olguların %40,5’inde son kontrolde ölçülen GİB değerleri 22 mmHg ve altındaydı. Göz başına ortalama diod lazer seans sayısı 1,480,73 olarak saptanırken birden fazla tedavi seansı gerektiren olgu sayısı 13 (%35,1) idi. Kullanılan antiglokomatöz tedavi etken madde sayısı tedavi öncesi 3,141,18 iken tedavi sonrası 2,761,23 olarak saptandı. Takip süresince olguların hiçbirinde fitizis bulbi ya da persistan hipotoni gelişmedi. Tart›flma: TSDLS uygulaması, dirençli glokom olgularında GİB düşürülmesinde etkin ve güvenilir bir tedavi yöntemidir. Aynı zamanda antiglokomatöz tedavi kullanımında azalma sağlayarak hastaların tedaviye uyumunu ve yaşam kalitesini artırmaktadır.Purpose: To evaluate the safety and efficacy of transscleral diode laser cyclophotocoagulation (TSDLC) in advanced glaucoma refractory to medical or surgical treatment. Material and Method: The data of subjects who were treated with TSDLC between 2009 and 2011 were retrospectively reviewed. Intraocular pressure before and after treatment, visual acuity, the number of medications and complications were analysed. Success was defined as final IOP of 6-22 mmHg with or without antiglaucomatous medications. Results: Thirty seven eyes of 37 patients were included in the study. Mean age of patients and mean follow-up time were 61.73±17.13 years (range: 19-80 years) and 8.06±5.81 months (range: 3-22 months), respectively. Mean pretreatment IOP was 38.68±8.94 mmHg and IOP was 26.46±11.34 mmHg (p >0.01) at the second week, whereas it was 24.97±10.84 mmHg (p>0.01) at the last visit. IOP of less than 22 mmHg was achieved in 40.5% of eyes at the last visit. Mean treatment number per eye was 1.48±0.73, and more than one treatment was required in 13 (35.1%) eyes. Preoperative and postoperative mean total antiglaucomatous medications were 3.14±1.18 and 2.76±1.23, respectively. No phthisis bulbi or persistent hypotonia developed during the follow-up period. Discussion: TSDLC is an effective and safe method for the treatment of refractory glaucoma. It also served to reduce the number of antiglaucoma medications, thus improving both the quality of life of the patients and their compliance to therapy

Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey

Background: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors