A latent class analysis of adolescents’ technology and interactive social media use: Associations with academics and substance use

Latent class analysis was used to identify patterns of technology and social media use among adolescents in a national study (n = 26,348). Multinomial logistic regression was used to examine associations between latent classes and academics and substance use. Results demonstrated four classes: Infrequent Users (55%), Interactive Users (21%), Television Watchers (14%), and Constant Users (10%). Compared to Infrequent Users, Interactive, and Constant Users had lower grades and higher alcohol and marijuana use. Television Watchers had lower grades and participated in fewer extracurricular activities compared to Infrequent Users, but there were no differences on substance use. Results show that adolescents with the most media‐intensive profiles were also at greater risk for poor academic outcomes and substance use.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153199/1/hbe2154.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/153199/2/hbe2154_am.pd

Poster 285 High Prevalence of Cranial Asymmetry May Exist in Infants with Neonatal Brachial Plexus Palsy (NBPP)

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147206/1/pmr2s184b.pd

Poster 285 High Prevalence of Cranial Asymmetry May Exist in Infants with Neonatal Brachial Plexus Palsy (NBPP)

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147206/1/pmr2s184b.pd

The Effect of a Cooler on the Rate of Heat Loss from a Horse Post-Exercise

Coolers are large wool blankets put on horses after exercising or bathing during cold weather. They are intended to allow moisture to travel away from the body of the horse while providing an insulating layer to help stabilize their body temperature and to prevent them from getting a chill. We tested the effectiveness of these wool coolers by comparing the rate of heat loss from a horse's skin with and without the added wool layer. Using the modeling software of FIDAP we were able to simulate the coupled processes of heat transfer from the horse?s skin and sweat evaporation. The model was run in FIDAP after determining an optimized mesh size and time step, which allowed accurate finite element modeling but maintained a reasonable run time. The model shows that the wool helps maintain a constant body temperature post exercise by providing an insulating layer. Since accurate diffusivity and conductivity values for wool and hair were hard to find, a sensitivity analysis was performed to determine the effect of an error on the temperature and mass profiles. After varying the diffusivities by one order of magnitude and the conductivities by 10%, the model determined that errors in these variables have little to no effect on horse body temperature approximations after one half hour

The Fundamental Value of Presence in Peer and Mutual Support: Observations from Telephone Support for High Risk Groups

“Being there” takes on considerable importance amidst recognition of the substantial deleterious effects of social isolation and loneliness. In particular, presence/ “being there” may be important features of the many contributions of peer and mutual support to health and wellbeing. This study examined how peer support may enhance a sense of presence based on a) contact data for years 2015-2016 from telephonic peer support services of Rutgers University Behavioral Health Care, and b) structured interviews with peer supporters and clients of these programs. Features of peer support that convey presence include a) 24/7 availability, b) structure of peer support around shared cultural roles – e.g., “Cop2Cop,” “Mom2Mom,” rather than shared diagnoses, c) training of supporters to provide a setting for open expression of feelings, and d) structural features such as IT systems that facilitate continuity by enabling those answering a call readily to refer to previous calls. Impacts include client reports of being understood, not being judged, and being cared for through routine follow-up, even though contact such as voicemails. Managers and peer supporters should recognize the diverse organizational and processes that convey presence/ “being there” and its central importance in peer and mutual support

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications

SummaryBromodomains are epigenetic readers that are recruited to acetyllysine residues in histone tails. Recent studies have identified non-acetyl acyllysine modifications, raising the possibility that these might be read by bromodomains. Profiling the nearly complete human bromodomain family revealed that while most human bromodomains bind only the shorter acetyl and propionyl marks, the bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 also recognize the longer butyryl mark. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks. None of the human bromodomains tested binds succinyl marks. We characterized structurally and biochemically the binding to different acyl groups, identifying bromodomain residues and structural attributes that contribute to specificity. These studies demonstrate a surprising degree of plasticity in some human bromodomains but no single factor controlling specificity across the family. The identification of candidate butyryl- and crotonyllysine readers supports the idea that these marks could have specific physiological functions

The Fundamental Value of Presence in Peer and Mutual Support: Observations from Telephone Support for High Risk Groups

“Being there” takes on considerable importance amidst recognition of the substantial deleterious effects of social isolation and loneliness. In particular, presence/ “being there” may be important features of the many contributions of peer and mutual support to health and wellbeing. This study examined how peer support may enhance a sense of presence based on a) contact data for years 2015-2016 from telephonic peer support services of Rutgers University Behavioral Health Care, and b) structured interviews with peer supporters and clients of these programs. Features of peer support that convey presence include a) 24/7 availability, b) structure of peer support around shared cultural roles – e.g., “Cop2Cop,” “Mom2Mom,” rather than shared diagnoses, c) training of supporters to provide a setting for open expression of feelings, and d) structural features such as IT systems that facilitate continuity by enabling those answering a call readily to refer to previous calls. Impacts include client reports of being understood, not being judged, and being cared for through routine follow-up, even though contact such as voicemails. Managers and peer supporters should recognize the diverse organizational and processes that convey presence/ “being there” and its central importance in peer and mutual support

Stop AAPI Hate National Report

This national report covers the 9,081 incident reports to Stop AAPI Hate from March 19, 2020 to June 30, 2021. The number of hate incidents reported to our center increased from 6,603 to 9,081 during April—June 2021. Of all incident reports, 4,548 hate incidents occurred in 2020 and 4,533 of hate incidents occurred in 2021.

Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

Cardiac neural crest cells contribute to important portions of the cardiovascular system including the aorticopulmonary septum and cardiac ganglion. Using replication incompetent avian retroviruses for precise high-resolution lineage analysis, we uncover a previously undescribed neural crest contribution to cardiomyocytes of the ventricles in Gallus gallus, supported by Wnt1-Cre lineage analysis in Mus musculus. To test the intriguing possibility that neural crest cells contribute to heart repair, we examined Danio rerio adult heart regeneration in the neural crest transgenic line, Tg(-4.9sox10:eGFP). Whereas the adult heart has few sox10+ cells in the apex, sox10 and other neural crest regulatory network genes are upregulated in the regenerating myocardium after resection. The results suggest that neural crest cells contribute to many cardiovascular structures including cardiomyocytes across vertebrates and to the regenerating heart of teleost fish. Thus, understanding molecular mechanisms that control the normal development of the neural crest into cardiomyocytes and reactivation of the neural crest program upon regeneration may open potential therapeutic approaches to repair heart damage in amniotes

Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

Cardiac neural crest cells contribute to important portions of the cardiovascular system including the aorticopulmonary septum and cardiac ganglion. Using replication incompetent avian retroviruses for precise high-resolution lineage analysis, we uncover a previously undescribed neural crest contribution to cardiomyocytes of the ventricles in Gallus gallus, supported by Wnt1-Cre lineage analysis in Mus musculus. To test the intriguing possibility that neural crest cells contribute to heart repair, we examined Danio rerio adult heart regeneration in the neural crest transgenic line, Tg(-4.9sox10:eGFP). Whereas the adult heart has few sox10+ cells in the apex, sox10 and other neural crest regulatory network genes are upregulated in the regenerating myocardium after resection. The results suggest that neural crest cells contribute to many cardiovascular structures including cardiomyocytes across vertebrates and to the regenerating heart of teleost fish. Thus, understanding molecular mechanisms that control the normal development of the neural crest into cardiomyocytes and reactivation of the neural crest program upon regeneration may open potential therapeutic approaches to repair heart damage in amniotes