4 research outputs found

    Level of serum uric acid in patients with preeclampsia compared to controls and its relation to feto-maternal outcome

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    Background: Uric acid is the final product of the purine metabolism in humans. The two final reactions in its production which catalyze the conversion of hypoxanthine to xanthine and the latter to uric acid are catalyzed by the enzyme xanthine oxidoreductase. The role of uric acid in the progression of prediabetes to diabetes has been known. Serum uric acid has been shown to be associated with cardiovascular disease, hypertension, and chronic kidney disease. The present study was done to see the level of uric acid in preeclampsia and  healthy pregnant controls, to relate serum uric acid results to the severity of hypertension and its relation to fetomaternal outcome in patients attending OPD at RMC Ajmer.Methods: 100 cases of preeclampsia of age group between 20-40 year and gestational age ≥28 weeks and 100 normal healthy women with similar gestational age and age group were included in the study and maternal serum uric acid was estimated in both groups.Results: Mean serum uric acid levels in preeclampsia was 7.65±081 mg/dl and 3.21±072 mg/dl in control group. Perinatal complication was more in case group, 74 % were preterm compared to 11% in control group. Mean birth weight in study group was 2.07 kg, of which 24% babies were VLBW 52% were LBW, and 24% babies had normal birth weight, in control group mean birth weight was 2.82 kg. The difference was found to be statistically significant (p value 0.001). In the study group, the MSUA concentration is found higher in LBW and VLBW babies compared to normal birth weight babies.Conclusions: There is a positive correlation between SUA & severity of preeclampsia, and a significant adverse fetal outcome is observed with raised MSUA in preeclamptic patients

    Isolation, Identification and quantitative analysis of Ellagic acid: a tannin compound from Helicteres isora

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    Plant derived secondary metabolites have widely attracted humans with great interest due to their immense medicinal and pharmacological properties. Ellagic acid, a natural phenolic compound found in many fruits exhibits both antimutagenic and anticarcinogenic activity. Qualitative analysis of the plant samples of Helicteres isora showed the presence of ellagic acid in in vivo (stem bark) and in vitro (callus) samples. Presence of isolated ellagic acid was confirmed by superimposable IR spectra of isolated and authentic samples of ellagic acid. The ellagic acid was further identified and confirmed by using different techniques such as TLC (Rf 0.41), and HPLC (Rt =5.546 min) studies

    Effect of Auxin and Cytokinin on Grafting and Growth of Sapling of Guava (Psidium guajava L.)

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    The experiment was conducted to study the effect of auxin and cytokinin on grafting and growth of sapling of guava (Psidium guajava L.) at department of Horticulture, College of Agriculture, ummedganj, KOTA, KVK Modal nursery Agriculture university Kota during the year of 2020-21.In the investigation, L-49 cultivar of guava (Psidium guajava L.) was selected as mother plant for obtaining scion bud. The foliar spray of NAA and BA (50 and 25 ppm each) either on rootstock or/and scion branch was applied 10 days prior to grafting. The most responsive treatments was foliar spray on rootstocks with BA at 25 ppm concentration. Rootstocks treated with BA (25 ppm) resulted in length of scion shoot after grafting (16.63 cm), diameter of sprouted scion (2.80 cm), diameter of rootstocks (3.41 cm), number of leaves (20.83), leaf area (24.76 cm2), number of lateral shoot (7.89) as compared to others treatments
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