25 research outputs found
Integrated nutrition management in pigeon pea intercropping systems for enhancing production and productivity in sustainable manner– A review
India is the largest producer and consumer of pulses in the world accounting for about 29 per cent of the world area and 19 per cent of the world’s production. In order to achieve self-sufficiency in pulses, the projected requirement by the year 2025 is estimated at 27.5 MT. To meet this requirement, the productivity needs to be enhanced to 1000 kg/ha, and an additional area of about 3-4 Mha has to be brought under pulses besides reducing post-harvest losses. This uphill task has to be accomplished under more severe production constraints, especially abiotic stresses, abrupt climatic changes, emergence of new species/ strains of insect-pests and diseases, and in-creasing deficiency of secondary and micronutrients in the soil. This requires a two-pronged proactive strategy, i.e. improving per unit productivity and reducing cost of production. The yield levels of pulses have remained low and stagnant, also area and total production. Among the pulses pigeon pea is second most important grain-legumes and major constraints in pigeon pea production is mostly grown in grown on marginal lands under rainfed agriculture and without nutrient management, hence are prone to abiotic stresses. Therefore, it is essential for higher production and productivity of pigeon pea, use of high yielding varieties which suitable for intercrop as well as sole cropping system with best nutrient management practices
Comparative trends of accidental to intentional mortalities over a one-year period at a tertiary care centre
Background: The trends of deaths due to unnatural incidents are on the rise each year throughout the world, including India. Incremental trends have been observed in all mortalities throughout the country. Although all these mortalities seem preventable, yet not much has been achieved over the years. Intentional mortalities are yet more preventable as compared to non intentional ones. The trends of unnatural deaths were observed at a tertiary care centre of the capital city of Rajasthan to determine the comparative magnitude of such fatalities to predict possible reasons for them.Methods: An observational study was carried out for a one year period (2013-14) at the Department of Forensic Medicine of an apex institution of the capital metropolitan city to determine the comparative trends of accidental to suicidal and homicidal deaths amongst the medico-legal autopsies carried out over the study period. The results were analysed to look into the probable reasons for these preventable deaths.Results: Accidental fatalities contributed maximally followed by suicides and homicides. All types of unnatural deaths were more commonly observed in young adult male population. Road accidents were the major offenders followed by thermal injuries and falls. Intentional fatalities due to self harm or other human beings shared a considerable burden among unexpected mortalities over the study region.Conclusions: Majority of the reported fatalities were preventable deaths occurring amongst the active and productive population and hence, it is of utmost importance to analyse such deaths to suggest remedial measures bring down the toll of such causalities
Net zero pole streets light by solar PV module
People have started to move non-conventional energy source. The energy generated from non-conventional energy source should be used in effective manner. It is also eco-friendly and viable for the environments. The solar street light is an innovation take for the sustainable growth through many policies like make in India. This paper proposes a net-zero pole streets lighting by solar PV module and the mean of net-zero is that no power demand from the grid. The proposed system consists of a PV panel, LEDs lamp, and micro-inverter. In this project we have used LEDs lights due to many advantages as compare to other lamps. This LEDs lighting is very efficient (very high efficiency) and cost effective (long life). In additional in this project we used micro-inverter. This micro-inverter is converted DC supply from the PV module into AC supply and its AC supply is feed to the grid through a net-meter. In this project battery is not required
Alcoholic Extract of Eclipta alba
As per WHO estimates, 80% of people around the world use medicinal plants for the cure and prevention of various diseases including cancer owing to their easy availability and cost effectiveness. Eclipta alba has long been used in Ayurveda to treat liver diseases, eye ailments, and hair related disorders. The promising medicinal value of E. alba prompted us to study the antioxidant, nontoxic, and anticancer potential of its alcoholic extract. In the current study, we evaluated the in vitro cytotoxic and antioxidant effect of the alcoholic extract of Eclipta alba (AEEA) in multiple cancer cell lines along with control. We have also evaluated its effect on different in vivo toxicity parameters. Here, we found that AEEA was found to be most active in most of the cancer cell lines but it significantly induced apoptosis in human breast cancer cell lines by disrupting mitochondrial membrane potential and DNA damage. Moreover, AEEA treatment inhibited migration in both MCF 7 and MDA-MB-231 cells in a dose dependent manner. Further, AEEA possesses robust in vitro antioxidant activity along with high total phenolic and flavonoid contents. In summary, our results indicate that Eclipta alba has enormous potential in complementary and alternative medicine for the treatment of cancer
Status of Early-Career Academic Cardiology, A Global Perspective
Early career academic cardiologists, whom many believe are an important component of the future of cardiovascular care, face a myriad of challenges. The Early Career Section Academic Working Group of the American College of Cardiology (ACC) along with senior leadership support, assessed the progress of this cohort from 2013–2016 with a global perspective. Data consisted of accessing National Heart Lung and Blood Institute (NHLBI) public information, American Heart Association and international organizations providing data, and a membership-wide survey. Although NHBLI increased funding of career development grants, only a small number of early career ACC members have benefited as funding of the entire cohort has decreased. Personal motivation, institutional support, and collaborators continued to be positive influential factors. Surprisingly, mentoring ceased to correlate positively with obtaining external grants. Totality of findings suggests that the status of early career academic cardiologists remain challenging; therefore, we recommend a set of attainable solutions
Recommended from our members
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
Comparative trends of accidental to intentional mortalities over a one-year period at a tertiary care centre
Background: The trends of deaths due to unnatural incidents are on the rise each year throughout the world, including India. Incremental trends have been observed in all mortalities throughout the country. Although all these mortalities seem preventable, yet not much has been achieved over the years. Intentional mortalities are yet more preventable as compared to non intentional ones. The trends of unnatural deaths were observed at a tertiary care centre of the capital city of Rajasthan to determine the comparative magnitude of such fatalities to predict possible reasons for them.Methods: An observational study was carried out for a one year period (2013-14) at the Department of Forensic Medicine of an apex institution of the capital metropolitan city to determine the comparative trends of accidental to suicidal and homicidal deaths amongst the medico-legal autopsies carried out over the study period. The results were analysed to look into the probable reasons for these preventable deaths.Results: Accidental fatalities contributed maximally followed by suicides and homicides. All types of unnatural deaths were more commonly observed in young adult male population. Road accidents were the major offenders followed by thermal injuries and falls. Intentional fatalities due to self harm or other human beings shared a considerable burden among unexpected mortalities over the study region.Conclusions: Majority of the reported fatalities were preventable deaths occurring amongst the active and productive population and hence, it is of utmost importance to analyse such deaths to suggest remedial measures bring down the toll of such causalities
Integrated nutrition management in pigeon pea intercropping systems for enhancing production and productivity in sustainable manner– A review
India is the largest producer and consumer of pulses in the world accounting for about 29 per cent of the world area and 19 per cent of the world’s production. In order to achieve self-sufficiency in pulses, the projected requirement by the year 2025 is estimated at 27.5 MT. To meet this requirement, the productivity needs to be enhanced to 1000 kg/ha, and an additional area of about 3-4 Mha has to be brought under pulses besides reducing post-harvest losses. This uphill task has to be accomplished under more severe production constraints, especially abiotic stresses, abrupt climatic changes, emergence of new species/ strains of insect-pests and diseases, and in-creasing deficiency of secondary and micronutrients in the soil. This requires a two-pronged proactive strategy, i.e. improving per unit productivity and reducing cost of production. The yield levels of pulses have remained low and stagnant, also area and total production. Among the pulses pigeon pea is second most important grain-legumes and major constraints in pigeon pea production is mostly grown in grown on marginal lands under rainfed agriculture and without nutrient management, hence are prone to abiotic stresses. Therefore, it is essential for higher production and productivity of pigeon pea, use of high yielding varieties which suitable for intercrop as well as sole cropping system with best nutrient management practices
Not Available
Not AvailableRough lemon fruits are highly acidic and possess greater nutraceutical value due to the consumers. Hence, the rough lemon juice squashes were prepared using varying juice concentration 50, 40, 30, 20 & 10 per cent and stored at ambient temperature (28 ± 3 ° C). Periodical observation were recorded at fresh (0), 3 and 6
month interval. Squash prepared with 40 per cent juice was found to be the best recipe with respect to organoleptic qualities viz. colour, flavour, taste and overall acceptability till 180 days of storage under ambient conditions.Not Availabl