Comparative study of neuroimaging features and clinical symptoms in patients with eclampsia

Background: Eclampsia is a life-threatening emergency that remains a major cause for feto-maternal morbidity and mortality. The purpose of our study was to access various computed tomographic scan (CT) findings in eclampsia patients and compare neurological symptoms with radiological findings. Methods: A prospective analytical study was undertaken in department of obstetrics and gynecology, J. K. Lon hospital, Kota during the period of 2019-2020. Women who presented as eclampsia and admitted in indoor wards were included in the study. Data analyzed included various maternal and fetal parameters, CT scan findings and outcome of pregnancy. Results: The incidence of eclampsia was 1.1% of total deliveries. High risk factors associated with eclampsia were primigravida (70%), maternal age (70% in 21-25 years age group), illiteracy (64%), inadequate antenatal care (96%), early gestation (68%). On CT scan findings 52% patients had abnormal CT scan findings of which most common was cerebral edema (57.7%). Parieto-occipital lobe was most common region to be affected. Altered sensorium was found to be significantly associated with abnormal CT scan findings.Conclusions: Eclampsia is a major cause of fetal and maternal morbidity and mortality.  CT scan in eclampsia have significant role in early diagnosis of patients with cerebral pathologies and these CT scan findings were associated with the level of consciousness and number of convulsive episodes.  Thus, CT scan helps in further management of these patients by multidisciplinary approach

Successful pregnancy outcome in a patient of chronic myeloid leukemia on imatinib therapy

Pregnancy and cancer is a complex situation. The coincidence chronic myeloid leukemia (CML) and pregnancy is an uncommon event, in part because CML occurs mostly in older age group. The management of CML, during pregnancy is a difficult problem because of potential effects of therapy on the mother and foetus. Imatinib, a tyrosine kinase inhibitor induces dramatic hematologic and cytogenetic responses in CML, but it is not recommended for use in pregnancy or if the patient plans to conceive. In literature there are very few reports of successful outcome of pregnancy while on imatinib. In this report we describe a successful pregnancy and labor under treatment with imatinib in a known case of CML.

Successful pregnancy outcome in a patient of chronic myeloid leukemia on imatinib therapy

Pregnancy and cancer is a complex situation. The coincidence chronic myeloid leukemia (CML) and pregnancy is an uncommon event, in part because CML occurs mostly in older age group. The management of CML, during pregnancy is a difficult problem because of potential effects of therapy on the mother and foetus. Imatinib, a tyrosine kinase inhibitor induces dramatic hematologic and cytogenetic responses in CML, but it is not recommended for use in pregnancy or if the patient plans to conceive. In literature there are very few reports of successful outcome of pregnancy while on imatinib. In this report we describe a successful pregnancy and labor under treatment with imatinib in a known case of CML.

Design of a Near Zero Ultraflatten Dispersion Photonic Crystal Fiber for Communication System

The proposed photonic crystal fiber presents dispersion flattened optical fiber (DF-PCF) for tailoring near zero ultraflatten dispersion of 0.61 ps/nm/km for 1.26 microm to 1.64 microm wide wavelength range or 380 nm flat band as well as low confinement losses of near 10-5 dB/km. The finite difference time domain (FDTD) method with transparent boundary condition (TBC) is employed to investigate the guiding properties. Through the simulation result it has been observed that it is possible to achieve near zero ultraflatten dispersion of 0.61 ps/nm/km for 1.26 microm to 1.64 microm with low confinement losses of the order less than 10-5 dB/km for second and third optical window.nbs