1,808 research outputs found

    Apollo extension system lsv studies. mission command and control

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    Steering system and control circuit for Lunar Surface Vehicle /LSV/ - Apollo projec

    Apollo logistic support systems nolab studies- mission command and control interim report

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    Vehicle stability, steering, and control system characteristics for Apollo logistic support of lunar mobile laboratory /Molab

    A polarizable interatomic force field for TiO2_2 parameterized using density functional theory

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    We report a classical interatomic force field for TiO2_2, which has been parameterized using density functional theory forces, energies, and stresses in the rutile crystal structure. The reliability of this new classical potential is tested by evaluating the structural properties, equation of state, phonon properties, thermal expansion, and some thermodynamic quantities such as entropy, free energy, and specific heat under constant volume. The good agreement of our results with {\em ab initio} calculations and with experimental data, indicates that our force-field describes the atomic interactions of TiO2_2 in the rutile structure very well. The force field can also describe the structures of the brookite and anatase crystals with good accuracy.Comment: Accepted for publication in Phys. Rev. B; Changes from v1 include multiple minor revisions and a re-write of the description of the force field in Section II

    Gaussian Process: A Smooth and Flexible Approach to Estimating Index Complementarities in Organizational Economics

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    A common question in organizational economics is how does a bundle or index of managerial practices or characteristics impact on firm or employee level outcomes. The presence of complementarities is of particular interest but we argue should not be restricted to particular functional forms like the multiplicative ‘interaction’ of slope coefficients. As an alternative we propose the use of Gaussian processes to estimate a smooth non-linear function of the management practices index/bundle

    Dryland Clovers: A Phytochemical Resource

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    Recent developments in the utilisation of phytoestrogens of red clover (Wuttke et al., 2002) have encouraged us to investigate a wider range of Trifolium species for metabolites which could provide new product opportunities. The phytochemistry of the agronomically-important Trifolium species white (Trifolium repens) and red (T. pratense) clovers has been investigated in some detail (Foo et al., 2000; Sivakumaran et al., 2004). However numerous other clover species have been neglected in agriculture due to agronomic issues or the fact they are annuals and require more intensive management. While some of these clover species have been studied for their genetic diversity (Marshall et al., 2002), investigations of the chemical composition of these specific species has not been reported

    Detecting delirium superimposed on dementia: diagnostic accuracy of a simple combined arousal and attention testing procedure

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    Detecting delirium superimposed on dementia (DSD) can be challenging because assessment partly relies on cognitive tests that may be abnormal in both conditions. We hypothesized that a combined arousal and attention testing procedure would accurately detect DSD. Patients aged ≥70 years were recruited from five hospitals across Europe. Delirium was diagnosed by physicians using DSM-5 criteria using information from nurses, carers, and medical records. Dementia was ascertained by the Informant Questionnaire on Cognitive Decline in the Elderly. Arousal was measured using the Observational Scale of Level of Arousal (OSLA), which assesses eye opening, eye contact, posture, movement, and communication. Attention was measured by participants signaling each time an “A” was heard when “S-A-V-E-A-H-A-A-R-T” was read out. The sample included 114 persons (mean age 82 years (SD 7); 54% women). Dementia alone was present in 25% (n = 28), delirium alone in 18% (n = 21), DSD in 27% (n = 31), and neither in 30% (n = 34). Arousal and attention was assessed in n = 109 (96%). Using OSLA, 83% participants were correctly identified as having delirium (sensitivity 85%, specificity 82%, AUROC 0.92). The attention task correctly classified 76% of participants with delirium (sensitivity 90%, specificity 64%, AUROC 0.80). Combining scores correctly classified 91% of participants with delirium (sensitivity 84%, specificity 92%, AUROC 0.94). Diagnostic accuracy remained high in the subgroup with dementia (93% correctly classified, sensitivity 94%, specificity 92%, AUROC 0.98). This combined arousal–attention assessment to detect DSD was brief yet had high diagnostic accuracy. Such an approach could have clinical utility for diagnosing DSD

    Optimizing end-labeled free-solution electrophoresis by increasing the hydrodynamic friction of the drag-tag

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    We study the electrophoretic separation of polyelectrolytes of varying lengths by means of end-labeled free-solution electrophoresis (ELFSE). A coarse-grained molecular dynamics simulation model, using full electrostatic interactions and a mesoscopic Lattice Boltzmann fluid to account for hydrodynamic interactions, is used to characterize the drag coefficients of different label types: linear and branched polymeric labels, as well as transiently bound micelles. It is specifically shown that the label's drag coefficient is determined by its hydrodynamic size, and that the drag per label monomer is largest for linear labels. However, the addition of side chains to a linear label offers the possibility to increase the hydrodynamic size, and therefore the label efficiency, without having to increase the linear length of the label, thereby simplifying synthesis. The third class of labels investigated, transiently bound micelles, seems very promising for the usage in ELFSE, as they provide a significant higher hydrodynamic drag than the other label types. The results are compared to theoretical predictions, and we investigate how the efficiency of the ELFSE method can be improved by using smartly designed drag-tags.Comment: 32 pages, 11 figures, submitted to Macromolecule
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