The dating game: Cultivation effects on relational investment

This study investigated the relationship between high exposure to reality television dating shows (Rock of Love, The Bachelorette, etc) and higher perceptions of alternatives to a current romantic relationship as explained by Cultivation Theory (Gerbner & Gross, 1973) and the Investment Model (Rusbult, 1980). This study employs interpersonal communication strategies to study media effects. Surveys were collected from 273 students at a large university. Results indicate higher exposure to reality television dating shows may cultivate a higher perception of alternatives to a current romantic relationship, however do not cultivate a belief that one\u27s partner believes themselves to have a high perception of alternatives. Various covariates are also tested including love styles and the perceived reality of television. Limitations and directions for future research are also discussed

The reliability of the swimming ergometer in obtaining VO₂ max of male and female age-group swimmers

This study was designed to test the reliability of the swimming ergonometer in obtaining VO2 max of male and female age-group swimmers

Long-range electron transfer in structurally engineered pentaammineruthenium (histidine-62) cytochrome c

In many biological processes, long-range electron transfer (ET) plays a key role. When the three-dimensional structures of proteins are accurately known, use of modified proteins and protein-protein complexes provides an experimental approach to study ET rates between two metal centers. For Ru(His)- modified proteins, the introduction of histidine residues at any desired surface location by site-directed mutagenesis opens the way for systematic investigations of ET pathways

Spectroscopic and redox properties of amine-unctionalized K_2[Os-^(II)(bpy)(CN)_4] complexes

We report the first examples of amine-functionalized K_2[Os^(II)(bpy)(CN)_4] (bpy = 2,2'-bipyridine) complexes. The tetracyanoosmate complexes were prepared by UV irradiation (λ = 254 nm) of K_4[Os^(II)(CN)_6] and primary amine-functionalized bpy ligands in acidic aqueous media. The aqueous solution pH dependences of the spectroscopic and redox properties of 4,4'- and 5,5'-substituted complexes have been investigated. The pendant amine functional groups and coordinated cyanide ligands are basic sites that can be sequentially protonated, thereby allowing systematic tuning of electrochemical and optical spectroscopic properties

Infrared point source variability between the Spitzer and MSX surveys of the Galactic mid-plane

We present a list of 552 sources with suspected variability, based on a comparison of mid-infrared photometry from the GLIMPSE I and MSX surveys, which were carried out nearly a decade apart. We were careful to address issues such as the difference in resolution and sensitivity between the two surveys, as well as the differences in the spectral responses of the instruments. We selected only sources where the IRAC 8.0 and MSX 8.28 micron fluxes differ by more than a factor of two, in order to minimize contamination from sources where the difference in fluxes at 8 micron is due to a strong 10 micron silicate feature. We present a subset of 40 sources for which additional evidence suggests variability, using 2MASS and MIPSGAL data. Based on a comparison with the variability flags in the IRAS and MSX Point-Source Catalogs we estimate that at least a quarter of the 552 sources, and at least half of the 40 sources are truly variable. In addition, we tentatively confirm the variability of one source using multi-epoch IRAS LRS spectra. We suggest that most of the sources in our list are likely to be Asymptotic Giant Branch stars.Comment: 47 pages, 12 Figures, 3 Tables, accepted for publication in A

Diet, nutrition, obesity and their role in arthritis

Obesity and poor nutrition, individually and together, have created costly musculoskeletal disease epidemic in the United States. Processed food, with abundant empty calories, has contributed greatly to our dietary woes. Much of the food consumed today is packed with calories but refined to the point that essential nutrients are lacking. Even worse, processed food may have ingredients added that are detrimental to good health. Abundant research has documented a close relationship between obesity, poor diet and orthopaedic problems. Dietary supplements have been proven to provide both disease prevention and therapeutic benefits. Unfortunately, many weight loss programs and methods are ineffective and possibly dangerous. Additionally, the FDA does not regulate the nutritional supplement industry and product quality is high variable. It is imperative that physicians treating patients with musculoskeletal complaints understand these disease producing relationships and have a network in place to refer patients to reputable weight loss entities and for high quality nutritional supplements

Automated Synthesis of 3‘-Metalated Oligonucleotides

We report the first synthesis of a metallonucleoside bound to a solid support and subsequent oligonucleotide synthesis with this precursor. Large-scale syntheses of metal-containing oligonucleotides are achieved using a solid support modified with [Ru(bpy)_2(impy‘)]^(2+) (bpy is 2,2‘-bipyridine; impy‘ is 2‘-iminomethylpyridyl-2‘-deoxyuridine). A duplex formed with the metal-containing oligonucleotide exhibits superior thermal stability when compared to the corresponding unmetalated duplex (Tm = 50 °C vs T_m = 48 °C). Electrochemical (E_(1/2) = 1.3 V vs NHE), absorption (λ_(max) = 480 nm), and emission (λ_(max) = 720 nm, τ = 44 ns, Φ = 0.11 × 10^(-3)) data for the ruthenium-modified oligonucleotides indicate that the presence of the oligonucleotide does not perturb the electronic properties of the ruthenium complex. The absence of any change in the emission properties upon duplex formation suggests that the [Ru(bpy)_2(impy)]^(2+) chromophore will be a valuable probe for DNA-mediated electron-transfer studies. Despite the relatively high Ru(III/II) reduction potential, oxidative quenching of photoexcited [Ru(bpy)_2(impy)]^(2+) does not lead to oxidative damage of guanine or other DNA bases

Description and life history of Cardicola alseae sp.n. (Trematoda : Sanguinicolidae)

Cardicola alseae is a blood dwelling trematode found in the fishes Salmo clarki henshawi and Salmo gairdneri gairdneri. Eggs which were ovoid in shape and non-operculate left the adult and passed to the gill capillaries of the secondary lamellae. The miracidium was ovoid, 0.070 mm. long by 0.052 mm. wide, covered with long cilia, and internally had an eyespot composed of 40 to 50 melanin granules. The miracidium was encased in an egg capsule which enlarged prior to eruption and release of the larva. Sporocysts were found in the visceral mass of the snail Oxytrema silicula (Gould). No mother sporocyst generation was identified. Percentage of infection was Iow, with infected snails having sporocysts of equal size, Usually one to three adult cercariae were present in each sporocyst, along with germinal balls in many stages of development. Cercariae were of the lophocercous, furcocercous, brevifurcate, apharyngeate type with furcae possessing claws on the tips. A delicate dorsal keel extended at least three-fourths the length of the body and reached its widest point at the dorsal bend of the body. If a cercaria touched the soft part of a potential host, it would attach, drop its tail, and penetrate within 15 to 20 minutes. The adult fluke was removed from blood vessels of the giIls, liver, mesenteries, and kidneys. It was covered with small spines, possessed a highly saccular testis, subterminal mouth, an H-shaped intestine, and lacked a pharynx. The fluke appeared to possess the characteristics of the genus Cardicola. C. alseae differs from the other two blood flukes found in salmonid fish in the morphology of the cercaria, size of the adult worm, number of rows of marginal spines, forrn of the testis and ovary, and shape of the excretory bladder and intestine

Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN41194621]

BACKGROUND: Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD). This condition is characterized by a particularly high incidence of coronary heart disease (CHD) and stroke, but is little studied thus far in randomised controlled trials. METHOD: Patients were recruited through 85 practices in the British Medical Research Council General Practice Research Framework and through nine hospital vascular clinics. The treatment regimen, which is double-blind and placebo-controlled, is bezafibrate 400 mg/day. The 1568 patients recruited represent 86% of those eligible at screening. RESULTS: None of the anticipated side effects (mainly gastrointestinal) differed between the two groups. Nearly 80% of the total person-years accrued at 3 years were spent on trial treatment. Bezafibrate significantly reduced total cholesterol by approximately 8.0% and low-density lipoprotein (LDL)-cholesterol by approximately 9.0%, and increased high-density lipoprotein (HDL)-cholesterol by approximately 11.0% initially, falling to about 6.0% at 3 years. Triglycerides were significantly reduced by about 23.0% and fibrinogen by about 14.0%. Plasma creatinine rose by approximately 11% in those on active treatment. All of these effects were highly significant (P < 0.0001). Bezafibrate had no effect on the level of C-reactive protein (CRP). CONCLUSION: The trial recruited an unusually high proportion of eligible patients, ensuring the general applicability of its results. The fibrinogen-lowering and lipid-modifying effects of bezafibrate were confirmed. Although bezafibrate lowers fibrinogen, it has no effect on CRP; this suggests that the reduction in fibrinogen is due to an effect on its metabolism rather than suppression of an inflammatory response

Measures for simulator evaluation of a helicopter obstacle avoidance system

The U.S. Army Aeroflightdynamics Directorate (AFDD) has developed a high-fidelity, full-mission simulation facility for the demonstration and evaluation of advanced helicopter mission equipment. The Crew Station Research and Development Facility (CSRDF) provides the capability to conduct one- or two-crew full-mission simulations in a state-of-the-art helicopter simulator. The CSRDF provides a realistic, full field-of-regard visual environment with simulation of state-of-the-art weapons, sensors, and flight control systems. We are using the CSRDF to evaluate the ability of an obstacle avoidance system (OASYS) to support low altitude flight in cluttered terrain using night vision goggles (NVG). The OASYS uses a laser radar to locate obstacles to safe flight in the aircraft's flight path. A major concern is the detection of wires, which can be difficult to see with NVG, but other obstacles--such as trees, poles or the ground--are also a concern. The OASYS symbology is presented to the pilot on a head-up display mounted on the NVG (NVG-HUD). The NVG-HUD presents head-stabilized symbology to the pilot while allowing him to view the image intensified, out-the-window scene through the HUD. Since interference with viewing through the display is a major concern, OASYS symbology must be designed to present usable obstacle clearance information with a minimum of clutter