1,178 research outputs found
Bedrock Geology of Bremer County, Iowa
https://ir.uiowa.edu/igs_ofm/1077/thumbnail.jp
Bedrock Geology of the Upper Iowa River Watershed Phase 4: Dorchester (Iowa) 7.5\u27 Quadrangle,
https://ir.uiowa.edu/igs_ofm/1058/thumbnail.jp
Workshop on Mars Sample Return Science
Martian magnetic history; quarantine issues; surface modifying processes; climate and atmosphere; sampling sites and strategies; and life sciences were among the topics discussed
Surficial Geology of the Upper Iowa River Watershed: Phase 4: Cresco Ne 7.5\u27 Quadrangle,
https://ir.uiowa.edu/igs_ofm/1055/thumbnail.jp
Bedrock Geology of the Upper Iowa River Watershed: Phase 4: Ridgeway 7.5\u27 Quadrangle,
https://ir.uiowa.edu/igs_ofm/1056/thumbnail.jp
Bedrock Geology of the Davenport West 7.5\u27 Quadrangle, Scott County, Iowa
https://ir.uiowa.edu/igs_ofm/1064/thumbnail.jp
PPC: an algorithm for accurate estimation of SNP allele frequencies in small equimolar pools of DNA using data from high density microarrays
Robust estimation of allele frequencies in pools of DNA has the potential to reduce genotyping costs and/or increase the number of individuals contributing to a study where hundreds of thousands of genetic markers need to be genotyped in very large populations sample sets, such as genome wide association studies. In order to make accurate allele frequency estimations from pooled samples a correction for unequal allele representation must be applied. We have developed the polynomial based probe specific correction (PPC) which is a novel correction algorithm for accurate estimation of allele frequencies in data from high-density microarrays. This algorithm was validated through comparison of allele frequencies from a set of 10 individually genotyped DNA's and frequencies estimated from pools of these 10 DNAs using GeneChip 10K Mapping Xba 131 arrays. Our results demonstrate that when using the PPC to correct for allelic biases the accuracy of the allele frequency estimates increases dramatically
Surficial Geology of the Upper Iowa River Watershed Phase 4: Ridgeway 7.5\u27 Quadrangle,
https://ir.uiowa.edu/igs_ofm/1057/thumbnail.jp
Surficial Geology of the Fertile SE 7.5\u27\u27 Quadrangle, Worth and Cerro Gordo Counties, Iowa
https://ir.uiowa.edu/igs_ofm/1075/thumbnail.jp
Surficial Geology of the Northwood 7.5\u27 Quadrangle,
https://ir.uiowa.edu/igs_ofm/1083/thumbnail.jp
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