Design and Manufacturing of the Carbon Fiber Roll Table

Backpacking and exploration of the great outdoors has surged in popularity in the 21st century, especially after the COVID-19 pandemic called for many to change their hobbies and interests. Additionally, many people explore new, remote locations as a way of breaking free from the chains of addiction to media and reliance on technology. Our team experienced this shift firsthand as our interest in backpacking and exploration has grown in recent years. Upon our reflection of this newfound hobby, we realized that the camping equipment market was missing one thing: a “do it all” backpacking table. Our team wanted to address this need in the backpacking community by creating a versatile, lightweight, and durable camping table that will help people experience the beauty found in nature. The product design, cost, and manufacturing process were all developed and chosen with these criteria in mind. In spring of 2022, we conducted market research through public polls and think tanks. From this research, we established a target market of individuals between the ages of 18-30 years old that are active backpackers and outdoor enthusiasts. This target market is a niche sub-category of the camping equipment and accessory market. Additionally, market research identified four consumer considerations: durability, versatility, weight, and affordability, all of which were considered during each phase of the design and production process. After establishing a market for our product concept, an outline of future work and procedures was established to manufacture our product. To begin, we would need to convert our drawings and ideas into an initial prototype. This phase of the manufacturing process was critical for success because it served as the foundation of what our product would be down the road. Additionally, this initial prototype was a proof of concept to prove that our design drawing was feasible. Next, our timeline called for product design and material changes based on our review of the initial prototype. These changes factored in physical limitations and manufacturing process restrictions that would be problematic in the future. For example, the primary design change was related to the coupler that holds all three table legs together at a single point. The initial design was bulky and expensive, so creating a more efficient coupler was necessary. All three previous stages of our process lead to a final product that resembled the product we set out to create. The final product was lightweight, versatile, and strong. The product itself was nearly flawless. In review of our final product, the next stage was completing a holistic profitability analysis of the end product since the primary mission of all businesses is to create income for stakeholders. We were able to complete this holistic analysis by combining data from processing time studies, material purchase orders, industry research, and target market surveys. Although we utilized this same data when making design and material decisions, the result of this end-stage financial study proved that our final product and design would be profitable

Economic impact of using risk models for eligibility selection to the International lung screening Trial

OBJECTIVES: Using risk models as eligibility criteria for lung screening can reduce race and sex-based disparities. We used data from the International Lung Screening Trial(ILST; NCT02871856) to compare the economic impact of using the PLCOm2012 risk model or the US Preventative Services' categorical age-smoking history-based criteria (USPSTF-2013). MATERIALS AND METHODS: The cost-effectiveness of using PLCOm2012 versus USPSTF-2013 was evaluated with a decision analytic model based on the ILST and other screening trials. The primary outcomes were costs in 2020 International Dollars ($), quality-adjusted life-years (QALY) and incremental net benefit (INB, in$ per QALY). Secondary outcomes were selection characteristics and cancer detection rates (CDR). RESULTS: Compared with the USPSTF-2013 criteria, the PLCOm2012 risk model resulted in $355 of cost savings per 0.2 QALYs gained (INB=$4294 at a willingness-to-pay threshold of $20 000/QALY (95$4205-$4383). Using the risk model was more cost-effective in females at both a 1.5$6616 and $6112, respectively), compared with males ($5221 and $695). The PLCOm2012 model selected more females, more individuals with fewer years of formal education, and more people with other respiratory illnesses in the ILST. The CDR with the risk model was higher in females compared with the USPSTF-2013 criteria (Risk Ratio = 7.67, 95 % CI: 1.87-31.38). CONCLUSION: The PLCOm2012 model saved costs, increased QALYs and mitigated socioeconomic and sex-based disparities in access to screening

The Moral Floor: A Philosophical Examination of the Connection Between Ethics and Business

ethical behavior, corporate social performance, corporate financial performance,

A MHz X-ray diffraction set-up for dynamic compression experiments in the diamond anvil cell

An experimental platform for dynamic diamond anvil cell (dDAC) research has been developed at the High Energy Density (HED) Instrument at the European X-ray Free Electron Laser (European XFEL). Advantage was taken of the high repetition rate of the European XFEL (up to 4.5 MHz) to collect pulse-resolved MHz X-ray diffraction data from samples as they are dynamically compressed at intermediate strain rates (≤10 3 s −1 ), where up to 352 diffraction images can be collected from a single pulse train. The set-up employs piezo-driven dDACs capable of compressing samples in ≥340 µs, compatible with the maximum length of the pulse train (550 µs). Results from rapid compression experiments on a wide range of sample systems with different X-ray scattering powers are presented. A maximum compression rate of 87 TPa s −1 was observed during the fast compression of Au, while a strain rate of ∼1100 s −1 was achieved during the rapid compression of N 2 at 23 TPa s −1

NGO assessment study report (Yellow Book)

http://sci.esa.int/science-e/www/object/index.cfm?fobjectid=49839#The NGO (New Gravitational wave Observatory) concept results from the reformulation of the LISA mission into a European-led mission. This report, the so-called Yellow Book, contains the results of ESA's assessment study (Phase 0/A) of the candidate L-class Cosmic Vision mission NGO

Sustainable Development and Corporate Performance: A Study Based on the Dow Jones Sustainability Index

competitive advantage, value creating, sustainable development, performance, Dow Jones Sustainability Index,