A novel systematic approach for analysing exploratory design ideation

Two kinds of design ideation process may be distinguished in terms of the problems addressed: (i) solution-focused, i.e. generating solutions to address a fixed problem specifying a desired output; and (ii) exploratory, i.e. considering different interpretations of an open-ended problem and generating associated solutions. Existing systematic analysis approaches focus on the former; the literature is lacking such an approach for the latter. In this paper, we provide a means to systematically analyse exploratory ideation for the first time through a new approach: Analysis of Exploratory Design Ideation (AEDI). AEDI involves: (1) open-ended ideation tasks; (2) coding of explored problems and solutions from sketches; and (3) evaluating ideation performance based on coding. We applied AEDI to 812 concept sketches from 19 open-ended tasks completed during a neuroimaging study of 30 professional product design engineers. Results demonstrate that the approach provides: (i) consistent tasks that stimulate problem exploration; (ii) a reliable means of coding explored problems and solutions; and (iii) an appropriate way to rank/compare designers’ performance. AEDI enables the benefits of systematic analysis (e.g. greater comparability, replicability, and efficiency) to be realised in exploratory ideation research, and studies using open-ended problems more generally. Future improvements include increasing coding validity and reliability

Insights into design concept similarity judgements

Similarity has been shown to influence various measures of outcome creativity in combinatorial design tasks, but the role of similarity during the combination of design concepts is unknown. As an initial step towards understanding design concept similarity we review prominent models of similarity processing, highlight challenges with adoption in a design context, and carry out an exploratory experimental investigation of design concept similarity perception. Similarity may be the result of structural alignment processing and similarity ratings appear to vary with the number of commonalities

Dopamine Beta Hydroxylase Genotype Identifies Individuals Less Susceptible to Bias in Computer-Assisted Decision Making

Computerized aiding systems can assist human decision makers in complex tasks but can impair performance when they provide incorrect advice that humans erroneously follow, a phenomenon known as “automation bias.” The extent to which people exhibit automation bias varies significantly and may reflect inter-individual variation in the capacity of working memory and the efficiency of executive function, both of which are highly heritable and under dopaminergic and noradrenergic control in prefrontal cortex. The dopamine beta hydroxylase (DBH) gene is thought to regulate the differential availability of dopamine and norepinephrine in prefrontal cortex. We therefore examined decision-making performance under imperfect computer aiding in 100 participants performing a simulated command and control task. Based on two single nucleotide polymorphism (SNPs) of the DBH gene, −1041 C/T (rs1611115) and 444 G/A (rs1108580), participants were divided into groups of low and high DBH enzyme activity, where low enzyme activity is associated with greater dopamine relative to norepinephrine levels in cortex. Compared to those in the high DBH enzyme activity group, individuals in the low DBH enzyme activity group were more accurate and speedier in their decisions when incorrect advice was given and verified automation recommendations more frequently. These results indicate that a gene that regulates relative prefrontal cortex dopamine availability, DBH, can identify those individuals who are less susceptible to bias in using computerized decision-aiding systems

International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020).

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation (tVNS) across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation(VNS) and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice

Morphology and Behavior of an Unusually Flexible Thoracic Limb in the Snapping Shrimp, Alpheus heterochelis

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Interaction and perception of interaction with 3D objects during design activities

Post study questionnaires are used in design studies to uncover data about design reasoning and intent. A study was conducted where activities the study participants performed were compared to the participants' statements about those activities, collected immediately after the study via a questionnaire. The goal was to explore the reliability of post study evaluations. Disagreements between performed and reported activities were identified, and recommendations made to, where possible, include more objective measures of design activity

“Bacteroides nordii” sp. nov. and “Bacteroides salyersae” sp. nov. Isolated from Clinical Specimens of Human Intestinal Origin

Two groups of unknown bacteria, which phenotypically resemble members of the Bacteroides fragilis group but phylogenetically display >5% 16S rRNA gene sequence divergence from their nearest validly described species, Bacteroides thetaiotaomicron, were characterized by phenotypic and molecular taxonomic methods. Phylogenetically and phenotypically, the unidentified bacteria displayed a relatively close association with each other. However, a 16S rRNA gene sequence divergence of approximately 4% between the two unknown bacteria, as well as distinguishable biochemical characteristics, demonstrates that these organisms are genotypically and phenotypically distinct, and each group may represent a previously unknown subline within the Bacteroides phylogenetic cluster. Subsequent DNA-DNA hybridization studies confirmed that the two novel organisms were indeed distinct from each other. The previously described species closest to both of them is B. thetaiotaomicron (approximately 94% sequence similarity), but they can be differentiated easily from B. thetaiotaomicron by virtue of not utilizing trehalose. DNA-DNA pairing studies also documented the separateness of the unknown species and B. thetaiotaomicron. Based on the phenotypic and phylogenetic findings, two new species, “Bacteroides nordii” sp. nov. and “Bacteroides salyersae” sp. nov, are proposed. The G+C content of the DNA is 41.4 mol% for Bacteroides nordii and 42.0 mol% for Bacteroides salyersae. The type strains of Bacteroides nordii and Bacteroides salyersae are WAL 11050 (ATCC BAA-998 or CCUG 48943) and WAL 10018 (ATCC BAA-997 or CCUG 48945), respectively