567 research outputs found

    A complex network perspective on clinical science

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    Contemporary classification systems for mental disorders assume that abnormal behaviors are expressions of latent disease entities. An alternative to the latent disease model is the complex network approach. Instead of assuming that symptoms arise from an underlying disease entity, the complex network approach holds that disorders exist as systems of interrelated elements of a network. This approach also provides a framework for the understanding of therapeutic change. Depending on the structure of the network, change can occur abruptly once the network reaches a critical threshold (the tipping point). Homogeneous and highly connected networks often recover more slowly from local perturbations when the network approaches the tipping point, potentially making it possible to predict treatment change, relapse, and recovery. In this article, we discuss the complex network approach as an alternative to the latent disease model and its implications for classification, therapy, relapse, and recovery.R34 MH086668 - NIMH NIH HHS; R01 AT007257 - NCCIH NIH HHS; R21 MH101567 - NIMH NIH HHS; R34 MH099311 - NIMH NIH HHS; R21 MH102646 - NIMH NIH HHS; K23 MH100259 - NIMH NIH HHS; R01 MH099021 - NIMH NIH HH

    Inter-Identity Autobiographical Amnesia in Patients with Dissociative Identity Disorder

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    Background: A major symptom of Dissociative Identity Disorder (DID; formerly Multiple Personality Disorder) is dissociative amnesia, the inability to recall important personal information. Only two case studies have directly addressed autobiographical memory in DID. Both provided evidence suggestive of dissociative amnesia. The aim of the current study was to objectively assess transfer of autobiographical information between identities in a larger sample of DID patients. Methods: Using a concealed information task, we assessed recognition of autobiographical details in an amnesic identity. Eleven DID patients, 27 normal controls, and 23 controls simulating DID participated. Controls and simulators were matched to patients on age, education level, and type of autobiographical memory tested. Findings: Although patients subjectively reported amnesia for the autobiographical details included in the task, the results indicated transfer of information between identities. Conclusion: The results call for a revision of the DID definition. The amnesia criterion should be modified to emphasize its subjective nature.Psycholog

    Nuevos desarrollos en el tratamiento del trastorno de pánico

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    El objetivo de este artículo consiste en proporcionar una revisión sobre los desarrollos recientes producidos en la investigación del tratamiento del trastorno de pánico. Aunque los estudios controlados apenas han comenzado a iniciarse en el momento presente, los defensores del uso de fármacos han apoyado de forma abrumadora la utilización de los inhibidores selectivos de recaptación de serotonina (selective serotonin reuptake inhibitors, SSRIs) como el fármaco apropiado para el tratamiento del pánico. Los terapeutas cognitivo-conductuales han documentado más a fondo la efectividad de sus aproximaciones, a la vez que han ocurrido desarrollos sorprendentes. Algunos datos sugieren que la exposición no necesita estar incluida para que ciertos tratamientos psicosociales sean efectivos, mientras que otros estudios han demostrado que los elementos cognitivos añaden poco más a la terapia de exposición. Otros desarrollos adicionales se han referido tanto al establecimiento de criterios estandarizados para evaluar el trastorno de pánico cuando se aplican indistintamente fármacos y tratamiento psicológico, como a la clarificación de métodos apropiados para planificar e interpretar intervenciones controladas

    Attention Training Toward and Away from Threat in Social Phobia: Effects on Subjective, Behavioral, and Physiological Measures of Anxiety

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    Social Phobics exhibit an attentional bias for threat in probe detection and probe discrimination paradigms. Attention training programs, whereby probes always replace nonthreat cues, reduce attentional bias for threat and self-reported anxiety. However, it remains unclear whether the therapeutic benefits of attention training result from people learning to disengage attention from threat cues or acquiring greater control over their attention by learning to deploy it flexibly. Moreover, researchers have seldom taken behavioral measures, and have never taken physiological measures of fear reduction. Investigating these questions, we found that training to disengage attention from threat is more effective than training to deploy it flexibly in social phobia. Indeed, the former condition reduced self-report, behavioral and physiological measures of anxiety.Psycholog
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