Managing creative eco-innovation: Structuring outputs from eco-innovation projects

Increasing legislative pressures and consumer awareness of environmentally efficient products are causing businesses to look at Sustainable Product Design (SPD) as an opportunity to improve their products and processes. Business and academia have identified a need for strategic approaches to SPD that will result in ‘step-change’ improvements in the design of products and services. Eco-innovation aims to develop new products and processes which provide customer and business value but significantly decrease environmental impact. Eco-innovation considers environmental aspects of the product at early stages of the New Product Development process. The research presented in this paper looks at the use of eco-innovation tools and focuses on idea generation within ecoinnovation processes. Two novel tools were developed to help review the results from previously conducted eco-innovation workshops: the Standard Design Process Form and the Product Ideas Tree (PIT) diagram. This paper shows the development of these two tools and demonstrates their potential to assist in structuring and documenting ideas throughout the eco-innovation process. The paper discusses the benefits of using such documentation and how it may subsequently improve the management of eco innovation throughout the design process

Isolating LCDs at end-of-life using active disassembly technology: A feasibility study

The European Union draft Waste Electrical and Electronic Equipment (WEEE) directive calls for the removal and separate treatment of liquid crystal displays (LCD). This aspect of the legislation will potentially have an important impact upon the future `End of Life' (EoL) processing of much WEEE. Active Disassembly using Smart Materials (ADSM) has been proven to have applicability in self-dismantling, nondestructive and rapid disassembly of small electronic products. This paper investigates the technical feasibility of removing LCD screens from IT communication products using ASDM technology. In this paper an option is suggested to cleanly separate LCD screens from printed circuit boards, utilizing an LCD bracket made from `shape memory polymer'. The case study products employed are Nokia Japanese J-Phones. Demonstration experiments with initial results are presented, and future developments discussed. SMB glass transformation temperatures (Tg) and time efficiency in disassembly are considered

Stabilised columnar mesophases formed by 1:1 mixtures of hexaalkoxytriphenylenes with a hexaphenyltriphenylene-based polymer

The synthesis is reported for a main chain polymer in which the repeat units are 2,3,6,7,10,11-hexaphenyltriphenylene moieties linked through flexible dodecyl chains. In compositions with a series of 2,3,6,7,10,11-hexakis(alkoxy)triphenylenes (HATn) this new polymer forms stable hexagonal columnar liquid crystal phases. These are investigated in detail using optical polarised microscopy (OPM), differential scanning calorimetry (DSC) and X-ray diffraction (XRD). In these mixtures, suppression of crystallisation and enhancement of the clearing temperatures leads to very wide liquid crystal ranges: much wider than those for the HATn materials on their own. For the longer chain HATn compounds (n = 12-16) a columnar rectangular phase is also observed. The enhancement of the liquid crystal phase range is attributed to stabilising complementary polytopic interactions between the planar aromatic moieties

The fate of the homoctenids (Tentaculitoidea) during the Frasnian-Famennian mass extinction (Late Devonian)

The homoctenids (Tentaculitoidea) are small, conical-shelled marine animals which are amongst the most abundant and widespread of all Late Devonian fossils. They were a principal casualty of the Frasnian-Famennian (F-F, Late Devonian) mass extinction, and thus provide an insight into the extinction dynamics. Despite their abundance during the Late Devonian, they have been largely neglected by extinction studies. A number of Frasnian-Famennian boundary sections have been studied, in Poland, Germany, France, and the United States. These sections have yielded homoctenids, which allow precise recognition of the timing of the mass extinction. It is clear that the homoctenids almost disappear from the fossil record during the latest Frasnian “Upper Kellwasser Event”. The coincident extinction of this pelagic group, and the widespread development of intense marine anoxia within the water column, provides a causal link between anoxia and the F-F extinction. Most notable is the sudden demise of a group, which had been present in rock-forming densities, during this anoxic event. One new species, belonging to Homoctenus is described, but is not formally named here

Dysplasia of the Upper Aerodigestive Tract Squamous Epithelium

Dysplasia of the oral, laryngeal and oropharyngeal stratified squamous epithelia is a microscopically defined change that may occur in clinically identifiable lesions including erythroplakia, leukoplakia and erythroleukoplakia, lesions that convey a heightened risk for carcinomatous progression. Dysplastic lesions have been classified microscopically according to degree of cytologic atypia and changes in architectural patterns, usually on a three part or four part gradation scale. Vocal cord epithelial lesions are graded according to either the Ljubljana or the World Health Organization (WHO) system whereas oral dysplasias are generally classified according to WHO criteria. Cytologically atypical cells are considered to represent precancerous changes predicting an increase risk for carcinomatous transformation. Inter- and intra-rater reliability studies among pathologists have disclosed low correlation coefficients for four part grading systems, whereas improved agreement is achieved (kappa correlation values) using the Ljubljana systems. Evidence forwarded by some studies supports the prognostic value of progressively severe dysplastic changes for carcinomatous transformation; however, some studies indicate that the presence of a clinically defined lesion without microscopic evidence of dysplasia also connotes increased risk for carcinomatous transformation. Loss of heterozygosity (LOH) at 3p and 9p microsatellite domains, DNA ploidy analysis and nuclear image analyses may have predictive value as molecular and histomorphological biomarkers

Tissue-engineered tracheal replacement in a child: a 4-year follow-up study

In 2010, a tissue-engineered trachea was transplanted into a 10-year-old child using a decellularized deceased donor trachea repopulated with the recipient's respiratory epithelium and mesenchymal stromal cells. We report the child's clinical progress, tracheal epithelialization and costs over the 4 years. A chronology of events was derived from clinical notes and costs determined using reference costs per procedure. Serial tracheoscopy images, lung function tests and anti-HLA blood samples were compared. Epithelial morphology and T cell, Ki67 and cleaved caspase 3 activity were examined. Computational fluid dynamic simulations determined flow, velocity and airway pressure drops. After the first year following transplantation, the number of interventions fell and the child is currently clinically well and continues in education. Endoscopy demonstrated a complete mucosal lining at 15 months, despite retention of a stent. Histocytology indicates a differentiated respiratory layer and no abnormal immune activity. Computational fluid dynamic analysis demonstrated increased velocity and pressure drops around a distal tracheal narrowing. Cross-sectional area analysis showed restriction of growth within an area of in-stent stenosis. This report demonstrates the long-term viability of a decellularized tissue-engineered trachea within a child. Further research is needed to develop bioengineered pediatric tracheal replacements with lower morbidity, better biomechanics and lower costs

Purifying Selection in Deeply Conserved Human Enhancers Is More Consistent than in Coding Sequences

(c) 2014 De Silva et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

A transient liquid-like phase in the displacement cascades of zircon, hafnon and thorite

The study of radiation effects in solids is important for the development of 'radiation-resistant' materials for fission-reactor applications'. The effects of heavy-ion irradiation in the isostructural orthosilicates zircon (ZrSiO4), hafnon (HfSiO4) and thorite (ThSiO4) are particularly important because these minerals are under active investigation for use as a waste form for plutonium-239 resulting from the dismantling of nuclear weapons(2-4). During ion irradiation, localized 'cascades' of displaced atoms can form as a result of ballistic collisions in the target material, and the temperature inside these regions may for a short time exceed the bulk melting temperature. Whether these cascades do indeed generate a localized liquid state(5-8) has, however, remained unclear. Here we investigate the irradiation-induced decomposition of zircon and hafnon, and find evidence for formation of a liquidlike state in the displacement cascades. Our results explain the frequent occurrence of ZrO2 in natural amorphous zircong(9-12) Moreover, we conclude that zircon-based nuclear waste forms should be maintained within strict temperature Limits, to avoid potentially detrimental irradiation-induced amorphization or phase decomposition of the zircon.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62853/1/395056a0.pd