1,615 research outputs found
How Messages about COVID-19 May Have Affected People’s Sense of Threat and Mental Health
COVID-19 has had profound effects on many physical, mental and social aspects of health. This study examined people’s fears and concerns about the virus, their experiences of being subjected to expert opinion and media portrayals of suffering from the virus, experiences of lockdown, and hopes and doubts for the future. We also examined how these relate to symptoms of depression, anxiety and stress. 180 participants completed an online survey exploring the themes of the study. Results suggest that in addition to
concerns of catching the virus themselves, participants were more concerned with passing it on to others. People found information provided by experts at times contradictory and confusing. There was a strong endorsement that the media exploited suffering and while there was a high desire to move to a more compassionate ‘caring and sharing world’, there were strong doubts that this would happen or that politicians would be able to navigate to that. More research is needed on how to present information about high levels of threat, tragic events and processes in order to avoid adding to, rather than reducing mental health difficulties, and generating unhelpful behaviours
PRS16 CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A COMPARISON OF ESTIMATES OF HEALTH-RELATED UTILITY (EQ5D) FROM SF36 DATA ALONE, THE SF36 PLUS LUNG FUNCTION DATA, AND THE SF36 PLUS THE ST. GEORGE'S RESPIRATORY QUESTIONNAIRE PLUS LUNG FUNCTION DATA
A comparison of intermediate and long-acting insulins in people with type 2 diabetes starting insulin: an observational database study
AimsInsulin is normally added to oral glucose-lowering drugs in people with type 2 diabetes when glycaemic control becomes suboptimal. We evaluated outcomes in people starting insulin therapy with neutral protamine Hagedorn (NPH), detemir, glargine or premixed insulins.MethodsInsulin-naïve people with type 2 diabetes (n = 8009), ≥ 35 years old, HbA(1c) ≥ 6.5% and begun on NPH (n = 1463), detemir (n = 357), glargine (n = 2197) or premix (n = 3992), were identified from a UK database of primary care records (The Health Improvement Network). Unadjusted and multivariate-adjusted analyses were conducted, with persistence of insulin therapy assessed by survival analysis.ResultsIn the study population (n = 4337), baseline HbA(1c) was 9.5 ± 1.6%, falling to 8.4 ± 1.5% over 12 months (change -1.1 ± 1.8%, p Discussion and conclusionIn routine clinical practice, people with type 2 diabetes commenced on NPH experienced a modest disadvantage in glycaemic control after 12 months compared with other insulins. When comparing the insulins, glargine achieved best HbA(1c) reduction, while premix showed greatest weight gain and the highest dose requirement, but had the best persistence of therapy.J. Gordon, R. D. Pockett, A. P. Tetlow, P. McEwan, P. D. Hom
Analytical determination of coronal parameters using the period ratio P<sub>1</sub>/2P<sub>2</sub>
<p>Context. In transverse coronal loop oscillations, two periodicities have been measured simultaneously and are interpreted as the fundamental
kink mode (with period P1) and the first harmonic (with period P2). Deviations of the period ratio P1/2P2 from unity provide
information about the extent of longitudinal structuring within the loop.</p>
<p>Aims. Here we develop an analytical approximation that describes the shift in P1/2P2 in terms of the ratio L/Λc of the length 2L of a
coronal loop and the density scale height Λc.</p>
<p>Methods. We study the MHD wave equations in a low β plasma using the thin tube approximation. Disturbances are described by a
differential equation which may be solved for various equilibrium density profiles, obtaining dispersion relations in terms of Bessel
functions. These dispersion relations may be used to obtain analytical approximations to the periods P1 and P2. We also present a
variational approach to determining the period ratio and show how the WKB method may be used.</p>
<p>Results. Analytical approximations to the period ratio P1/2P2 are used to shed light on the magnitude of longitudinal structuring in
a loop, leading to a determination of the density scale height. We apply our formula to the observations in Verwichte et al. (2004) and
Van Doorsselaere et al. (2007), obtaining the coronal density scale height.</p>
<p>Conclusions. Our simple formula and approximate approaches highlight a useful analytical tool for coronal seismology. We demonstrate
that P1/2P2 is linked to the density scale height, with no need for estimates of other external parameters. Given the accuracy of
current observations, our formula provides a convenient means of determining density scale heights.</p>
Flowering Phenology Change and Climate Warming in Southwestern Ohio
Global surface temperature has increased markedly over the last 100 years. This increase has a variety of implications for human societies, and for ecological systems. One of the most obvious ways ecosystems are affected by global climate change is through alteration of organisms’ developmental timing (phenology). We used annual botanical surveys that documented the first flowering for an array of species from 1976 to 2003 to examine the potential implications of climate change for plant development. The overall trend for these species was a progressively earlier flowering time. The two earliest flowering taxa (Galanthus and Crocus) also exhibited the strongest shift in first flowering. We detected a significant trend in climate suggesting higher temperatures in winter and spring over the sampling interval and found a significant relationship between warming temperatures and first flowering time for some species. Although 60% of the species in our study flowered earlier over the sampling interval, the remaining species exhibited no statistically detectable change. This variation in response is ostensibly associated with among-species variation in the role of climate cues in plant development. Future work is needed to isolate specific climate cues, and to link plant phenology to the physiological processes that trigger plant development
ES5 RIMONABANT FOR THE TREATMENT OF OVERWEIGHT AND OBESE INDIVIDUALS AT INCREASED CARDIOMETABOLIC RISK:AN ECONOMIC EVALUATION USING DISCRETE EVENT SIMULATION
PDB44 THE COST-EFFECTIVENESS OF SAXAGLIPTIN VERSUS SULFONYLUREA (SU) IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS (T2DM) IN GERMANY
Decision-making accuracy of soccer referees in relation to markers of internal and external load
This study examined the relationships between the decision-making performances of soccer referees and markers of physiological load. Following baseline measurements and habituation procedures, 13 national-level male referees completed a novel Soccer Referee Simulation whilst simultaneously adjudicating on a series of video-based decision-making clips. The correctness of each decision was assessed in relation to the mean heart rate (HR), respiratory rate (RR), minute ventilation (VE), perceptions of breathlessness (RPE-B) and local muscular (RPE-M) exertion and running speeds recorded in the 10-s and 60-s preceding decisions. There was a significant association between decision-making accuracy and the mean HR (p = 0.042; VC = 0.272) and RR (p = 0.024, VC = 0.239) in the 10-s preceding decisions, with significantly more errors observed when HR ≥ 90% of HRmax (OR, 5.39) and RR ≥ 80% of RRpeak (OR, 3.34). Decision-making accuracy was also significantly associated with the mean running speeds performed in the 10-s (p = 0.003; VC = 0.320) and 60-s (p = 0.016; VC = 0.253) preceding decisions, with workloads of ≥250 m·min−1 associated with an increased occurrence of decisional errors (OR, 3.84). Finally, there was a significant association between decision-making accuracy and RPE-B (p = 0.021; VC = 0.287), with a disproportionate number of errors occurring when RPE-B was rated as “very strong” to “maximal” (OR, 7.19). Collectively, the current data offer novel insights into the detrimental effects that high workloads may have upon the decision-making performances of soccer referees. Such information may be useful in designing combined physical and decision-making training programmes that prepare soccer referees for the periods of match play that prove most problematic to their decision-making
Solar feature tracking in both spatial and temporal domains
A new method for automated coronal loop tracking, in both spatial and temporal
domains, is presented. The reliability of this technique was tested with TRACE 171A observations.
The application of this technique to a flare-induced kink-mode oscillation, revealed a
3500 km spatial periodicity which occur along the loop edge. We establish a reduction in oscillatory
power, for these spatial periodicities, of 45% over a 322 s interval. We relate the reduction
in oscillatory power to the physical damping of these loop-top oscillations
- …