Perceptions of Higher Education Faculty of the Quality, Benefits, and Consequences of Dual Enrollment Participation

In this qualitative study, the researcher sought to address a gap in the literature related to identifying and understanding perceptions of collegiate faculty of the quality, benefits, and consequences of dual enrollment participation upon students, their higher educational organization, and their own career paths. Study participants included 36 collegiate faculty and administrators with faculty standing employed full-time by Columbus State University who have taught dual enrollment students in college settings, high school settings, or in both settings. The sequential qualitative design identified perceptions of the participants through application of a survey instrument. The initial phase of data collection was followed by a subsequent phase utilizing a semi-structured focus group identifying agreement and disagreement with the initial phase results and research literature regarding the quality, benefits, and consequences of dual enrollment participation, thus providing deeper understanding of the perceptions of faculty at Columbus State University. Research literature generally suggests many immediate and future benefits to students obtained by participating in dual enrollment but also suggests some level of disagreement between some stakeholders regarding the advantages and disadvantages of dual enrollment. Likewise, the study results indicate faculty at Columbus State University possess positive perceptions of the benefit to students, the institution, and to their own instructional experience, but also possess reservations . Results carry implications for institutions, their students, and their faculty for future implementation, sustainment, and assessment of dual enrollment instruction and partnerships

USC South Campus: A Last Look at Modernism

This is a class project from ARTH 542: American Architecture taught at the University of South Carolina by Lydia Mattice Brandt in Spring 2016. With more Americans attending college than ever before; urban renewal; racial integration; the expansion of coeducation; and the architecture community’s advocacy for holistic relationship between planning, architecture, and landscape architecture, the American college campus developed rapidly and dramatically in the mid twentieth century. Using the University of South Carolina’s Columbia Campus as a case study, this project explores the history of American architecture in the mid-twentieth century

Serum autoantibody measurement for the detection of hepatocellular carcinoma

Background: Individuals with liver disease, and especially those with Hepatitis B or C, are at an increased risk of developing hepatocellular carcinoma (HCC) which is the third most common cause of cancer-related death worldwide. Inadequate screening tests largely account for presentation of advanced tumours and high mortality rates. Early detection of HCC amongst high-risk groups is paramount in improving prognosis. This research aimed to further characterise the previously described humoral immune response raised to tumour-associated antigens (TAAs) in the serum of patients with HCC.Methods: Serum from 96 patients with confirmed HCC, 96 healthy controls matched for age and sex, 78 patients with confirmed liver cirrhosis and 91 patients with confirmed chronic liver disease were analysed for the presence of IgG autoantibodies raised to 41 recombinant TAAs/antigen fragments by ELISA.Results: Varying autoantibody specificities (97–100%) and sensitivities (0–10%) were observed to individual TAAs. A 21-antigen panel achieved a specificity of 92% and sensitivity of 45% for the detection of HCC. This same panel identified 21% of 169 high-risk controls as having elevated autoantibody levels. A reproducible panel of 10 antigens achieved a specificity of 91% and sensitivity of 41% in HCC. 15% of 152 high-risk controls gave positive results with this panel.Conclusions: This minimally invasive blood test has the potential to offer advantages over currently available tools for the identification of HCC amongst pre-disposed patients. Results are comparable to current gold standards in HCC (Ultrasonography) and to similar tests in other cancers (EarlyCDT-Lung)

Evaluation of Esterified Hyaluronic Acid as Middle Ear–Packing Material

OBJECTIVE To evaluate the efficacy of esterified hyaluronic acid (MeroGel) as a middle ear (ME)–packing material. DESIGN Randomized controlled trial. MATERIAL Twenty-four guinea pigs. INTERVENTION Group 1, MeroGel-treated animals (n = 10), bilateral wounding of ME mucosa with 5 of the animals receiving the MeroGel packing in the left ME and 5 of the animals receiving MeroGel in the right ME; group 2, absorbable gelatin sponge–treated animals (n = 10), with the same experimental protocol as in group 1 except that the absorbable gelatin sponge was the packing material; group 3, untreated animals (n = 4), unilateral wounding of the left ME mucosa in 2 animals and in 2 animals in the right ME, with no packing material. Auditory brainstem recordings were performed for all groups before the ME operation and 5 days and 6 weeks after the operation. RESULTS Auditory brainstem response recordings at postoperative day 5 showed that all ears with ME packing had hearing losses in the frequency range of 500 to 4000 Hz. The recovery of hearing acuity at postoperative week 6 was significantly better in group 1 (MeroGel-treated) guinea pigs compared with group 2 (the absorbable gelatin sponge–treated) animals. In group 2 animals, 20% of the packing material remained in the ME cavities and new bone formation was observed, while in group 1 animals, there was less packing material in the ME and no formation of new bone. CONCLUSIONS MeroGel is a nonototoxic packing material with a high level of biocompatibility for ME mucosa; it is an effective supportive material following ME surgery and is easily expelled from the ME cavity.Arch Otolaryngol Head Neck Surg. 2001;127:534-539--

Injectable form of cross-linked hyaluronan is effective for middle ear wound healing

Objectives: Two studies were designed to investigate a hyaluronan (HA) gel for middle ear (ME) wound healing. Methods: We used a guinea pig model of ME wound healing. In a long-term study, we performed a comparison of hearing and ME inflammation in 3 groups. Group 1 (n = 8) underwent bilateral wounding of ME mucosa and unilateral packing of the ME with HA gel (Sepragel). Group 2 (n = 6) was the same as group 1 except that the packing was absorbable bovine collagen sponges (Gelfoam). Group 3, the control group (n = 14), had operated, unpacked ears. In a short-term study, we investigated ME retention of HA gel at 1 and 2 weeks (n = 16). Results: At 1 week, all ears showed decreased distortion product otoacoustic emissions (DPOAEs) and auditory brain stem responses (ABRs) secondary to ME packing and postsurgical inflammation. The controls recovered preoperative DPOAEs and ABRs by week 2. Group 1 had decreased low-frequency DPOAEs at weeks 2 and 6, but their high-frequency DPOAEs and ABRs recovered to preoperative values by week 6. Group 2 had hearing losses that persisted throughout the study. Group 1 showed normal ME and inner ear histologic characteristics. Group 2 showed inflammatory cells within the ME and cochleas. Group 1 showed less packing retention than did group 2 at week 6 (p = 016). Eighty-five percent of the HA packing remained at 1 week, and 73% at 2 weeks. Conclusions: Hyaluronan gel was a relatively safe and effective ME packing material in our animal model. </jats:sec