498 research outputs found

    Death and prudential deprivation

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    Dying is (sometimes) bad for the dier because it prevents her from being the subject of wellbeing she otherwise would (the deprivation account). I argue for this from a (plausible) principle about which futures are bad for a prudential subject (the future-comparison principle). A strengthening of this principle yields that death is not always bad, and that the badness of death does not consist in that it destroys the dier

    F21RS SGB No. 8 (Department funding)

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    A Bill To amend the Student Government Cod

    F21RS SGB No. 16 (Grad Student Exceptions)

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    A Bill To amend the Student Government Code to revise Section 208: Remove generally; graduate student exception

    F21RS SGB No. 20 (FLC Director)

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    A Bill To amend the Student Government Code Regarding Responsibilities of the FLC Directo

    F21RS SGB No. 4 (Water Bottle Refill)

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    A Bill To Appropriate a maximum of $8,000.00 from the Surplus account to fund 6 water bottle refill stations

    Whole genome scan in commercial angus cattle for quantitative trait loci influencing growth, carcass, and reproductive traits

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    The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.Title from PDF of title page (University of Missouri--Columbia, viewed on January 6, 2010).Vita.Thesis advisor: Jeremy Taylor."July 2009"Ph. D. University of Missouri-Columbia 2009.Experimental designs historically used for quantitative trait loci (QTL) mapping in cattle have captured a limited number of parental chromosomes and therefore have only detected the few heterozygous QTL within these parents. Consequently, most genome scans have found only a small number of QTL to influence any one trait and genetic improvement in cattle by marker-assisted selection (MAS) has been hindered by this limited information. By using a twenty-nine generation mapping population (N=1,769) that represents the major commercial bloodlines within American Angus, we have captured the majority of the chromosomes represented within the breed. Our experimental design allows the flexibility of using several different analytical approaches which exploit both the full pedigree information and within family variation. This design maximizes the potential for identifying all of the QTL of large effect that segregate within Angus cattle. Our analyses revealed that a large number of QTL of moderate to large effect influence all of the economically important growth and carcass traits, even for traits under strong selection. Despite considerable selection pressure by Angus producers on economically important traits over the past 30 years there remains a wide range in the allele frequency of trait-enhancing QTL. Thus genetic improvement programs that use information at only one, or a few QTL will have little value in beef cattle. Strategies must quickly be devised to simultaneously test for multiple QTL for MAS to be economically viable. The identification of multiple QTL underlying variation in carcass, growth and reproductive traits in this study will assist in the development of QTL tests. Ideally, QTL information will be integrated with available phenotypic data for the estimation of EPDs in cattle to allow producers to select for genetically superior animals.Includes bibliographical reference
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