Radioisotope Distribution in Visceral Organs of White Mice

White mice, previously medicated over a three week period with reserpine, thyroxine, ascorbic acid and streptomycin were given 0.3 Microcurie or radioactive phosphorus³² by intramuscular injection. After 24 hours the mice were sacrificed, ten organs removed, and the amount of radioactivity retained was recorded in counts per minute per gram. Results showed males retained more of the isotope than females in all organs except gonads and brain. Liver, intestine, and kidney retained more of the isotope than other organs with each medication. With the reserpine medicated animals there was less radioactivity retained by ten organs. The control group had the next most, followed by ascorbic acid, and streptomycin-medicated animals. Greatest retention of the isotope was in the thryoxin-medicated groups