382 research outputs found
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Dissociation between the impact of evidence on eye movement target choice and confidence judgements
It has been suggested that the evidence used to support a decision to move our eyes and the confidence we have in that decision are derived from a common source. Alternatively, confidence may be based on further post-decisional processes. In three experiments we examined this. In Experiment 1, participants chose between two targets on the basis of varying levels of evidence (i.e., the direction of motion coherence in a Random-Dot-Kinematogram). They indicated this choice by making a saccade to one of two targets and then indicated their confidence. Saccade trajectory deviation was taken as a measure of the inhibition of the non-selected target. We found that as evidence increased so did confidence and deviations of saccade trajectory away from the non-selected target. However, a correlational analysis suggested they were not related. In Experiment 2 an option to opt-out of the choice was offered on some trials if choice proved too difficult. In this way we isolated trials on which confidence in target selection was high (i.e., when the option to opt-out was available but not taken). Again saccade trajectory deviations were found not to differ in relation to confidence. In Experiment 3 we directly manipulated confidence, such that participants had high or low task confidence. They showed no differences in saccade trajectory deviations. These results support post-decisional accounts of confidence: evidence supporting the decision to move the eyes is reflected in saccade control, but the confidence that we have in that choice is subject to further post-decisional processes
Situational Judgment Tests: An Overview of Development Practices and Psychometric Characteristics
Situational judgment tests (SJTs) are popular assessment methods often used for personnel selection and promotion. SJTs present problem scenarios to examinees, who then evaluate each response option for addressing the issue described in the scenario. As guidance for practitioners and researchers alike, this paper provides experience- and evidence-based best practices for developing SJTs: writing scenarios and response options, creating response instructions, and selecting a response format. This review describes scoring options, including key stretching and within-person standardization. The authors also describe research on psychometric issues that affect SJTs, including reliability, validity, group differences, presentation modes, faking, and coaching
Vitrified hillforts as anthropogenic analogues for nuclear waste glasses – project planning and initiation
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The programming of sequences of saccades
Saccadic eye movements move the high-resolution fovea to point at regions of interest. Saccades can only be generated serially (i.e., one at a time). However, what remains unclear is the extent to which saccades are programmed in parallel (i.e., a series of such moments can be planned together) and how far ahead such planning occurs. In the current experiment, we investigate this issue with a saccade contingent preview paradigm. Participants were asked to execute saccadic eye movements in response to seven small circles presented on a screen. The extent to which participants were given prior information about target locations was varied on a trial-by-trial basis: participants were aware of the location of the next target only, the next three, five, or all seven targets. The addition of new targets to the display was made during the saccade to the next target in the sequence. The overall time taken to complete the sequence was decreased as more targets were available up to all seven targets. This was a result of a reduction in the number of saccades being executed and a reduction in their saccade latencies. Surprisingly, these results suggest that, when faced with a demand to saccade to a large number of target locations, saccade preparation about all target locations is carried out in paralle
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Understanding representations of uncertainty, an eye-tracking study – Part 2: The effect of expertise
As the ability to make predictions regarding uncertainty information
representing natural hazards increases, an important question for those
designing and communicating hazard forecasts is how visualizations of
uncertainty influence understanding amongst the intended, potentially
varied, target audiences. End-users have a wide range of differing expertise
and backgrounds, possibly influencing the decision-making process they
undertake for a given forecast presentation. Our previous, Part 1 study
(Mulder et al., 2023) examined how the presentation of uncertainty
information influenced end-user decision making. Here, we shift the focus to
examine the decisions and reactions of participants with differing areas of expertise
(meteorology, psychology, and graphic-communication students) when presented
with varied hypothetical forecast representations (boxplot, fan plot, or
spaghetti plot with and without median lines) using the same eye-tracking
methods and experiments. Participants made decisions about a fictional
scenario involving the choices between ships of different sizes in the face
of varying ice thickness forecasts. Eye movements to the graph area and key
and how they changed over time (early, intermediate, and later viewing
periods) were examined. More fixations (maintained gaze on one location)
and more fixation time were spent on the graph and key during early and
intermediate periods of viewing, particularly for boxplots and fan plots.
The inclusion of median lines led to less fixations being made on all graph
types during early and intermediate viewing periods. No difference in eye
movement behaviour was found due to expertise; however, those with greater
expertise were more accurate in their decisions, particularly during more
difficult scenarios. Where scientific producers seek to draw users to the
central estimate, an anchoring line can significantly reduce cognitive load,
leading both experts and non-experts to make more rational decisions. When
asking users to consider extreme scenarios or uncertainty, different prior
expertise can lead to significantly different cognitive loads for processing
information, with an impact on one's ability to make appropriate decisions.</p
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Understanding representations of uncertainty, an eye-tracking study – Part 1: The effect of anchoring
Geoscience communicators must think carefully about how
uncertainty is represented and how users may interpret these
representations. Doing so will help communicate risk more effectively, which
can elicit appropriate responses. Communication of uncertainty is not just a
geosciences problem; recently, communication of uncertainty has come to the
forefront over the course of the COVID-19 pandemic, but the lessons learned
from communication during the pandemic can be adopted across geosciences as
well. To test interpretations of environmental forecasts with uncertainty,
a decision task survey was administered to 65 participants who saw different
hypothetical forecast representations common to presentations of
environmental data and forecasts: deterministic, spaghetti plot with and
without a median line, fan plot with and without a median line, and box plot
with and without a median line. While participants completed the survey,
their eye movements were monitored with eye-tracking software. Participants'
eye movements were anchored to the median line, not focusing on possible
extreme values to the same extent as when no median line was present.
Additionally, participants largely correctly interpreted extreme values from
the spaghetti and fan plots, but misinterpreted extreme values from the box
plot, perhaps because participants spent little time fixating on the key.
These results suggest that anchoring lines, such as median lines, should
only be used where users should be guided to particular values and where
extreme values are not as important in data interpretation. Additionally,
fan or spaghetti plots should be considered instead of box plots to reduce
misinterpretation of extreme values. Further study on the role of expertise
and the change in eye movements across the graph area and key is explored in more detail in the companion paper to this study (Williams et al., 2023; hereafter Part 2).</p
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The effectiveness of personalised food choice advice tailored to an individual’s socio-demographic, cognitive characteristics, and sensory preferences
Personalised dietary advice has become increasingly popular, currently however most approaches are based on an individual’s genetic and phenotypic profile whilst largely ignoring other determinants such as socio economic and cognitive variables. This paper provides novel insights by testing the effectiveness of personalised healthy eating advice concurrently tailored to an individual’s socio-demographic group, cognitive characteristics, and sensory preferences. We first used existing data to build a synthetic dataset based on information from 3654 households (Study 1a), and then developed a cluster model to identify individuals characterised by similar socio- demographic, cognitive, and sensory aspects (Study 1b). Finally, in Study 2 we used the characteristics of 8 clusters to build 8 separate personalised food choice advice and assess their ability to motivate the increased consumption of fruit and vegetables and decreased intakes of saturated fat and sugar. We presented 218 par- ticipants with either generic UK Government “EatWell” advice, advice that was tailored to their allocated cluster (matched personalised), or advice tailored to a different cluster (unmatched personalised). Results showed that, when compared to generic advice, participants that received matched personalised advice were significantly more likely to indicate they would change their diet. Participants were similarly motivated to increase vegetable consumption and decrease saturated fat intake when they received unmatched personalised advice, potentially highlighting the power of providing alternative food choices. Overall, this study demonstrated that the power of personalizing food choice advice, based on a combination of individual characteristics, can be more effective than current approaches in motivating dietary change. Our study also emphasizes the viability of addressing population health through automatically delivered web-based personalised advice
Magnetotransport properties of high quality Co:ZnO and Mn:ZnO single crystal pulsed laser deposition films: Pitfalls associated with magnetotransport on high resistivity materials
Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells
Background:
Persin is a plant toxin that displays synergistic cytotoxicity with tamoxifen in human breast cancer cell lines. Here, we examined the ability of persin to circumvent tamoxifen resistance and delineated the intracellular signalling pathways involved.
Methods:
The induction of apoptosis in tamoxifen-resistant and -sensitive breast cancer cells was measured by flow cytometry following treatment with persin±tamoxifen. Markers of endoplasmic reticulum stress (ERS) were analysed following treatment, and their causal role in mediating persin-induced apoptosis was determined using chemical inhibitors and RNA interference.
Results:
Cells that were resistant to an apoptotic concentration of tamoxifen maintained an apoptotic response to persin. Persin-induced apoptosis was associated with an increase in markers of ERS, that is, CHOP expression and XBP-1 splicing and was decreased by CHOP siRNA. The CASP-4 inhibitor Z-YVAD-FMK markedly inhibited persin-induced apoptosis in both tamoxifen-sensitive and -resistant cells.
Conclusion:
The cytotoxic effects of persin are CASP-4 dependent and mediated by CHOP-dependent and -independent ERS signalling cascades. Increased ERS signalling contributes to persin-induced reversal of tamoxifen resistance
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The concurrent programming of saccades
Sequences of saccades have been shown to be prepared concurrently however it remains unclear exactly what aspects of those saccades are programmed in parallel. To examine this participants were asked to make one or two target-driven saccades: a reflexive saccade; a voluntary saccade; a reflexive then a voluntary saccade; or vice versa. During the first response the position of a second target was manipulated. The new location of the second saccade target was found to impact on second saccade latencies and second saccade accuracy showing that some aspects of the second saccade program are prepared in parallel with the first. However, differences were found in the specific pattern of effects for each sequence type. These differences fit well within a general framework for saccade control in which a common priority map for saccade control is computed and the influence of saccade programs on one another depends not so much on the types of saccade being produced but rather on the rate at which their programs develop
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