16 research outputs found
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Ohio State 4-H Green Building
Congressionally directed project to pay in part for construction of a building on the Ohio State University campus
Microsc Microanal
Abstract A microcompressor is a precision mechanical device that flattens and immobilizes living cells and small organisms for optical microscopy, allowing enhanced visualization of sub-cellular structures and organelles. We have developed an easily fabricated device, which can be equipped with microfluidics, permitting the addition of media or chemicals during observation. This device can be used on both upright and inverted microscopes. The apparatus permits micrometer precision flattening for nondestructive immobilization of specimens as small as a bacterium, while also accommodating larger specimens, such as Caenorhabditis elegans, for long-term observations. The compressor mount is removable and allows easy specimen addition and recovery for later observation. Several customized specimen beds can be incorporated into the base. To demonstrate the capabilities of the device, we have imaged numerous cellular events in several protozoan species, in yeast cells, and in Drosophila melanogaster embryos. We have been able to documen
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ERP indices of performance monitoring and feedback processing in psychosis: A meta-analysis
BackgroundAlthough individuals with, or at risk for, psychotic disorders often show difficulties with performance monitoring and feedback processing, findings from studies using event-related potentials (ERPs) to index these processes are not consistent. This meta-analytic review focused on studies of two different indexes of performance monitoring, the early error-related negativity (ERN; nâŻ=âŻ25) and the later error positivity (Pe; nâŻ=âŻ17), and one index of feedback processing, the feedback negativity (FN; nâŻ=âŻ6).MethodsWe evaluated whether individuals (1) with psychotic disorders, or (2) at heightened risk for these disorders differ from healthy controls in available studies of the ERN, Pe, and FN.ResultsThere was a significant, large ERN reduction in those with psychosis (gâŻ=âŻ-0.96) compared to controls, and a significant, moderate ERN reduction in those at-risk (gâŻ=âŻ-0.48). In contrast, there were uniformly non-significant, small between-group differences for Pe and FN (gsâŻâ€âŻ|0.16|).ConclusionsThe results reveal a differential pattern of impairment in psychosis. Early performance monitoring (ERN) impairments are substantial among those with psychotic disorders in general and may be a useful vulnerability indicator for these disorders. However, later performance monitoring (Pe) and basic feedback processing (FN) appear to be relatively spared in psychosis
The European rescue of the Washington Consensus? EU and IMF lending to Central and Eastern European countries
The latest global financial crisis has allowed the International Monetary Fund (IMF) a spectacular comeback. But despite its notorious reputation as a staunch advocate of restrictive economic policies, the Fund has displayed less preference for austerity in recent crisis lending. Though widely welcomed as overdue, the IMFâs shift away from what John Williamson coined the âWashington Consensusâ was met with resistance from the European Union (EU) where it concerned Central and Eastern European (CEE) countries. The situation of hard-hit Hungary, Latvia, and Romania propelled unprecedented cooperation between the IMF and the EU, in which the EU has very actively promoted orthodox measures in return for loans. We argue that this represents a European rescue of the Washington Consensus. The case of Latvia is paradigmatic for the profound disagreements between an austerity-demanding EU and a less austere IMF. The IMFâs stance contradicts conventional wisdom about the organization as the guardian of economic orthodoxy. To solve this puzzle, we shed light on three complementary factors of (non)learning that have shaped the EUâs relations vis-Ă -vis CEE borrowing countries in comparison to the IMFâs: (1) a disadvantageous institutional setting; (2) vociferous creditor coalitions; (3) the precarious eurozone project
DataSheet_1_Trophic interactions between primary consumers appear to weaken during periods of synchrony.zip
Our understanding of synchrony between populations from different taxonomic groups has been centered on predatorâprey dynamics in simple systems but has rarely been examined in complex predatorâprey systems. In addition to trophic interactions such as predatorâprey dynamics, there is some evidence that exogenous factor such as climatic variation may facilitate synchrony between different taxonomic groups. Using three longitudinal datasets on quail (Colinus virginianus) and cotton rats (Sigmodon hispidus) we examined 1) the consistency of synchrony across time and space, 2) the relative influence of trophic interactions vs. exogenous factors on synchrony and 3) if trophic interactions were positively associated with synchrony between populations. We found evidence of consistent synchrony in cotton rat and bobwhite populations at both the site and regional levels. We found that trophic interactions between cotton rats and bobwhite were associated with relative synchrony between these populations, but these interactions appeared to weaken in years of greater synchrony. We did not find evidence that exogenous factors influenced relative synchrony at the regional level. Given the lack of a clear mechanistic explanation of the patterns observed in our data, we propose an alternative climate-mediated predation framework to explain synchrony in complex predatorâprey systems. This framework includes both classic bottom-up theories of regulation while integrating trophic interactions via components of the shared predator hypothesis.</p
Longitudinal stability of social cognition in schizophrenia: A 5-year follow-up of social perception and emotion processing.
BackgroundIndividuals with schizophrenia exhibit marked and disproportional impairment in social cognition, which is associated with their level of community functioning. However, it is unclear whether social cognitive impairment is stable over time, or if impairment worsens as a function of illness chronicity. Moreover, little is known about the longitudinal associations between social cognition and community functioning.MethodForty-one outpatients with schizophrenia completed tests of emotion processing (Mayer-Salovey-Caruso Emotional Intelligence Test, MSCEIT) and social perception (Relationships Across Domains, RAD) at baseline and approximately five years later. Stability of performance was assessed using paired t-tests and correlations. Longitudinal associations between social cognition and community functioning (Role Functioning Scale, RFS) were assessed using cross-lagged panel correlation analysis.ResultsPerformance on the two social cognition tasks were stable over follow-up. There were no significant mean differences between assessment points [p'sâ„0.20, Cohen'sd'sâ€|0.20|], and baseline performance was highly correlated with performance at follow-up [Ï'sâ„0.70, ICCâ„0.83, p's<0.001]. The contemporaneous association between social cognition and community functioning was moderately large at follow-up [Ï=0.49, p=0.002]. However, baseline social cognition did not show a significant longitudinal influence on follow-up community functioning [z=0.31, p=0.76].ConclusionsThese data support trait-like stability of selected areas of social cognition in schizophrenia. Cross-lagged correlations did not reveal a significant unidirectional influence of baseline social cognition on community functioning five years later. However, consistent with the larger literature, a moderately large cross-sectional association between social cognition and community functioning was observed. Based on stability and cross-sectional associations, these results suggest that social cognition might have short-term implications for functional outcome rather than long-term consequences