20,556 research outputs found
On the Intracluster Medium in Cooling Flow & Non-Cooling Flow Clusters
Recent X-ray observations have highlighted clusters that lack entropy cores.
At first glance, these results appear to invalidate the preheated ICM models.
We show that a self-consistent preheating model, which factors in the effects
of radiative cooling, is in excellent agreement with the observations.
Moreover, the model naturally explains the intrinsic scatter in the L-T
relation, with ``cooling flow'' and ``non-cooling flow'' systems corresponding
to mildly and strongly preheated systems, respectively. We discuss why
preheating ought to be favoured over merging as a mechanism for the origin of
``non-cooling flow'' clusters.Comment: 4 pages, to appear in the proceedings of the "Multiwavelength
Cosmology" Conference held in Mykonos, Greece, June 2003, ed. M. Plionis
(Kluwer
Predictive validity of the HCR-20 for inpatient aggression:the effect of intellectual disability on accuracy
BackgroundPeople with intellectual disability (ID) account for a large proportion of aggressive incidents in secure and forensic psychiatric services. Although the Historical, Clinical, Risk Management 20 (HCR-20) has good predictive validity in inpatient settings, it does not perform equally in all groups and there is little evidence for its efficacy in those with ID.MethodA pseudo-prospective cohort study of the predictive efficacy of the HCR-20 for those with ID (n = 109) was conducted in a UK secure mental health setting using routinely collected risk data. Performance of the HCR-20 in the ID group was compared with a comparison group of adult inpatients without an ID (n = 504). Analysis controlled for potential covariates including security level, length of stay, gender and diagnosis.ResultsThe HCR-20 total score was a significant predictor of any aggression and of physical aggression for both groups, although the area under the curve values did not reach the threshold for a large effect size. The clinical subscale performed significantly better in those without an ID compared with those with. The ID group had a greater number of relevant historical and risk management items. The clinicians' summary judgment significantly predicted both types of aggressive outcomes in the ID group, but did not predict either in those without an ID.ConclusionsThis study demonstrates that, after controlling for a range of potential covariates, the HCR-20 is a significant predictor of inpatient aggression in people with an ID and performs as well as for a comparison group of mentally disordered individuals without ID. The potency of HCR-20 subscales and items varied between the ID and comparison groups suggesting important target areas for improved prediction and risk management interventions in those with ID
Models of the ICM with Heating and Cooling: Explaining the Global and Structural X-ray Properties of Clusters
(Abridged) Theoretical models that include only gravitationally-driven
processes fail to match the observed mean X-ray properties of clusters. As a
result, there has recently been increased interest in models in which either
radiative cooling or entropy injection play a central role in mediating the
properties of the intracluster medium. Both sets of models give reasonable fits
to the mean properties of clusters, but cooling only models result in fractions
of cold baryons in excess of observationally established limits and the
simplest entropy injection models do not treat the "cooling core" structure
present in many clusters and cannot account for entropy profiles revealed by
recent X-ray observations. We consider models that marry radiative cooling with
entropy injection, and confront model predictions for the global and structural
properties of massive clusters with the latest X-ray data. The models
successfully and simultaneously reproduce the observed L-T and L-M relations,
yield detailed entropy, surface brightness, and temperature profiles in
excellent agreement with observations, and predict a cooled gas fraction that
is consistent with observational constraints. The model also provides a
possible explanation for the significant intrinsic scatter present in the L-T
and L-M relations and provides a natural way of distinguishing between clusters
classically identified as "cooling flow" clusters and dynamically relaxed
"non-cooling flow" clusters. The former correspond to systems that had only
mild levels (< 300 keV cm^2) of entropy injection, while the latter are
identified as systems that had much higher entropy injection. This is borne out
by the entropy profiles derived from Chandra and XMM-Newton.Comment: 20 pages, 15 figures, accepted for publication in the Astrophysical
Journa
Effects of negative energy balance on liver gene and protein expression during the early postpartum period and its impacts on dairy cow fertility
End of project reportNegative energy balance (NEB) is a severe metabolic affecting high yielding dairy cows early post partum with both concurrent and latent negative effects on cow fertility as well as on milk production and cow health. The seasonal nature of Irish dairy production necessitates high cow fertility and a compact spring calving pattern in order to maximise grass utilisation. Poor dairy cow reproductive performance currently costs the Irish cattle industry in excess of €400 million annually. High milk yields have been associated with lower reproductive efficiency, and it has been suggested that this effect is probably mediated through its effects on the energy balance of the cow during lactation. The modern high genetic merit dairy cow prioritises nutrient supply towards milk production in early lactation and this demand takes precedence over the provision of optimal conditions for reproduction. In this study we used the bovine Affymetrix 23,000 gene microarray, which contains the most comprehensive set of bovine genes to be assembled and provides a means of investigating the modifying influences of energy balance on liver gene expression.
Cows in severe negative energy balance (SNEB) in early lactation showed altered hepatic gene expression in metabolic processes as well as a down regulation of the insulin-like growth factor (IGF) system, where insulin like growth factor-1 (IGF-1), growth hormone receptor variant 1A (GHR1A) and insulin-like growth factor binding protein-acid labile subunit (IGFBP-ALS) were down regulated compared to the cows in the moderate negative energy balance MNEB group, consistent with a five-fold reduction in systemic concentrations of IGF1 in the SNEB group.Cows in SNEB showed elevated expression of key genes involved in the inflammatory response such as interleukin-8 (IL-8). There was a down regulation of genes involved in cellular growth in SNEB cows and moreover a negative regulator of cellular proliferation (HGFIN) was up regulated in SNEB cows, which is likely to compromise adaptation and recovery from NEB.
The puma method of analysis revealed that 417 genes were differentially regulated by EB (P<0.05), of these genes 190 were up-regulated while 227 were down-regulated, with 405 genes having known biological functions. From Ingenuity Pathway Analysis (IPA), lipid catabolism was found to be the process most affected by differences in EB status
Vine and Fruit Responses to Supplementary Irrigation and Canopy Management
Drip irrigation at 0.0, 0.2 or 0.4 of weekly Class A Pan evaporation was applied to grapevines cv. Shiraz in the Barossa Valley of South Australia. Irrigation resulted in a significant increase in yield and vegetative growth but also significantly changed wine composition and wine spectral measures. Canopy management by shoot positioning and treatment with ethephon, both designed to increase fruit exposure to sunlight, resulted in significant but small changes in wine quality measures. The implications of these treatments for the improvement of wine quality from irrigated vines are discussed
Salmonella in Irish pig farms; prevalence, antibiotic resistance and molecular epidemiology
The objective was to examine the prevalence of Salmonella in manure from 30 Irish pig farms and to characterize any recovered isolates in order to assess potential risks and epidemiological relationships. Salmonella was detected in the manure from finisher pigs in 50% of the herds investigated. S. Typhimurium was the predominant serotype recovered and the most common phage types were DT104 and DT104b. Nineteen of the 29 Salmonella isolates recovered were resistant to one or more antibiotics and 15 of these (all Typhimurium) were multi-resistant
Providing Self-Aware Systems with Reflexivity
We propose a new type of self-aware systems inspired by ideas from
higher-order theories of consciousness. First, we discussed the crucial
distinction between introspection and reflexion. Then, we focus on
computational reflexion as a mechanism by which a computer program can inspect
its own code at every stage of the computation. Finally, we provide a formal
definition and a proof-of-concept implementation of computational reflexion,
viewed as an enriched form of program interpretation and a way to dynamically
"augment" a computational process.Comment: 12 pages plus bibliography, appendices with code description, code of
the proof-of-concept implementation, and examples of executio
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Making Sense of Family Deaths in Urban Senegal: Diversities, Contexts, and Comparisons
Despite calls for cross-cultural research, Minority world perspectives still dominate death and bereavement studies, emphasizing individualized emotions and neglecting contextual diversities. In research concerned with contemporary African societies, on the other hand, death and loss are generally subsumed within concerns about AIDS or poverty, with little attention paid to the emotional and personal significance of a death. Here, we draw on interactionist sociology to present major themes from a qualitative study of family deaths in urban Senegal, theoretically framed through the duality of meanings-in-context. Such themes included family and community as support and motivation; religious beliefs and practices as frameworks for solace and (regulatory) meaning; and material circumstances as these are intrinsically bound up with emotions. Although we identify the experience of (embodied, emotional) pain as a common response across Minority and Majority worlds, we also explore significant divergencies, varying according to localized contexts and broader power dynamics
Barrier and internal wave contributions to the quantum probability density and flux in light heavy-ion elastic scattering
We investigate the properties of the optical model wave function for light
heavy-ion systems where absorption is incomplete, such as Ca
and O around 30 MeV incident energy. Strong focusing effects
are predicted to occur well inside the nucleus, where the probability density
can reach values much higher than that of the incident wave. This focusing is
shown to be correlated with the presence at back angles of a strong enhancement
in the elastic cross section, the so-called ALAS (anomalous large angle
scattering) phenomenon; this is substantiated by calculations of the quantum
probability flux and of classical trajectories. To clarify this mechanism, we
decompose the scattering wave function and the associated probability flux into
their barrier and internal wave contributions within a fully quantal
calculation. Finally, a calculation of the divergence of the quantum flux shows
that when absorption is incomplete, the focal region gives a sizeable
contribution to nonelastic processes.Comment: 16 pages, 15 figures. RevTeX file. To appear in Phys. Rev. C. The
figures are only available via anonynous FTP on
ftp://umhsp02.umh.ac.be/pub/ftp_pnt/figscat
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