20 research outputs found
Theoretical and experimental activities on opacities for a good interpretation of seismic stellar probes
Opacity calculations are basic ingredients of stellar modelling. They play a
crucial role in the interpretation of acoustic modes detected by SoHO, COROT
and KEPLER. In this review we present our activities on both theoretical and
experimental sides. We show new calculations of opacity spectra and comparisons
between eight groups who produce opacity spectra calculations in the domain
where experiments are scheduled. Real differences are noticed with real
astrophysical consequences when one extends helioseismology to cluster studies
of different compositions. Two cases are considered presently: (1) the solar
radiative zone and (2) the beta Cephei envelops. We describe how our
experiments are performed and new preliminary results on nickel obtained in the
campaign 2010 at LULI 2000 at Polytechnique.Comment: 6 pages, 4 figures, invited talk at SOHO2
A Quasi Method of Characteristics with Applications to Fluid Lines with Frequency Dependent Wall Shear and Heat Transfer
Professor Streeter has given a fine summary of the basic numerical techniques for unsteady flows, presuming that equation One exception, well known to Professor Streeter and included in several of his references, is the simpler case of laminar rather than turbulent friction for low frequency excitation. Only minor variations in the equations are necessary. A much greater departure from equation 4 Numbers in brackets designate Additional References at end of discussion. at intermediate frequencies in turbulent flow. Apparently because of a little-understood resonance of ring vortices, the step response of a tube may contain significant oscillations. Wavelengths of the complicated patterns are about 25 and 50 diameters. (Further information is forthcoming in a thesis by Margolis.) The report also discusses the details of numerical application of the quasi method of characteristics to large amplitude transients, with illustrations. Readers should know that the paper and this discussion represent a highly selected rather than comprehensive review of the important literature on numerical methods for unsteady flow calculations in channels and tubes. T. P. Propson 6 The author has conducted a thorough review of the most popular techniques currrently employed to numerically evaluate the effect of transient flows in liquid piping systems. His discussion of the relative advantages and disadvantages of both the characteristics (explicit) and centered implicit method is excellent; of particular interest to the writer were the author's comments relative to the occurrence of instabilities and inaccuracies occasionally encountered during application of the implicit techniques. Recent unpublished work by the writer has confirmed these problems. When frictional effects are very important, the writer would suggest that equations (64) It may be shown that the error introduced into the integration of the friction term by these finite-difference equations is usually about one-half of that introduced by equations (30) and (31)
Biomedical Discovery Acceleration, with Applications to Craniofacial Development
The profusion of high-throughput instruments and the explosion of new results in the scientific literature, particularly in molecular biomedicine, is both a blessing and a curse to the bench researcher. Even knowledgeable and experienced scientists can benefit from computational tools that help navigate this vast and rapidly evolving terrain. In this paper, we describe a novel computational approach to this challenge, a knowledge-based system that combines reading, reasoning, and reporting methods to facilitate analysis of experimental data. Reading methods extract information from external resources, either by parsing structured data or using biomedical language processing to extract information from unstructured data, and track knowledge provenance. Reasoning methods enrich the knowledge that results from reading by, for example, noting two genes that are annotated to the same ontology term or database entry. Reasoning is also used to combine all sources into a knowledge network that represents the integration of all sorts of relationships between a pair of genes, and to calculate a combined reliability score. Reporting methods combine the knowledge network with a congruent network constructed from experimental data and visualize the combined network in a tool that facilitates the knowledge-based analysis of that data. An implementation of this approach, called the Hanalyzer, is demonstrated on a large-scale gene expression array dataset relevant to craniofacial development. The use of the tool was critical in the creation of hypotheses regarding the roles of four genes never previously characterized as involved in craniofacial development; each of these hypotheses was validated by further experimental work