998 research outputs found
Formality theorems for Hochschild chains in the Lie algebroid setting
In this paper we prove Lie algebroid versions of Tsygan's formality
conjecture for Hochschild chains both in the smooth and holomorphic settings.
In the holomorphic setting our result implies a version of Tsygan's formality
conjecture for Hochschild chains of the structure sheaf of any complex manifold
and in the smooth setting this result allows us to describe quantum traces for
an arbitrary Poisson Lie algebroid. The proofs are based on the use of
Kontsevich's quasi-isomorphism for Hochschild cochains of R[[y_1,...,y_d]],
Shoikhet's quasi-isomorphism for Hochschild chains of R[[y_1,...,y_d]], and
Fedosov's resolutions of the natural analogues of Hochschild (co)chain
complexes associated with a Lie algebroid.Comment: 40 pages, no figure
Recurrent Non-Hodgkin’s lymphoma in the uterine cervix: a case report and a review of the literature
Background. Lymphomas are a heterogeneous group of malignant lymphoproliferative diseases. As primary localization, the most common histological subtype of female genital lymphomas is a Non-Hodgkin Lymphoma (NHL), the diffuse large B-cell type. However cervical relapse of NHL is a very rare condition (0.3%). Case presentation. A 42-year-old Peruvian woman experienced relapse of NHL with uterine localization. She complained at first of abnormal vaginal bleeding and stranguria. The cervical biopsy performed showed a diffuse large B-cell lymphoma in the uterine cervix. The lack of clinical studies on this topic and its rarity make this type of recurrence very difficult to treat. Conclusions. In case of a woman with vaginal bleeding and history of NHL, a disease relapse should always be considered, and a biopsy should be performed to confirm the diagnosis. © 2023, EDRA S.p.A. All rights reserved
Viticultural Climate Indexes and Their Role in The Prediction of Anthocyanins and Other Flavonoids Content in Seedless Table Grapes
Background: Viticulture bioclimatic indexes like the Heliothermal Index (HI), Cool Night
Index (CI), and Dryness Index (DI), can be used to assess the influence of climate on grapes’ quality.
Methods: HI, CI, and DI + total seasonal irrigation were utilized to assess the effect of climate on
the flavonoids content and composition of two Vitis vinifera seedless varieties, ‘Summer Royal’ and
‘Crimson Seedless’, both grown in Apulia (Southern Italy). Results: The flavonoids content was
significantly affected by variety and climate conditions on the base of HI, CI, and DI + total seasonal
irrigation. Factor analysis applied to climate indexes and flavonoids showed that anthocyanins and
flavonols were negatively and positively correlated to CI in both varieties, respectively. Additionally,
warmer night temperatures determined higher fla-van-3-ols. HI increase promoted anthocyanins,
flavonols, and flavan-3-ols content in Crimson Seedless, whilst it induced an opposite trend in
Summer Royal. Finally, DI + total seasonal irrigation showed to be positively linked to flavonols
content and negatively linked to anthocyanins content just in the case of Crimson Seedless. Significant
regression models were also determined between climate indexes and productive parameters (i.e.,
yield, TSS, TA, pH, bunch, and berry weight). Conclusions: Climate indexes HI, CI, and DI + total
seasonal irrigation showed an effect on quality grape parameters like flavonoids and contributed to
building predictive models when new climatic zones are going to be evaluated for the production of
table grapes
Genotyping-by-sequencing of a melon (Cucumis melo L.) germplasm collection from a secondary center of diversity highlights patterns of genetic variation and genomic features of different gene pool.
Melon (Cucumis melo L.) is one of the most important horticultural species, which includes several taxonomic groups. With the advent of next-generation sequencing, single nucleotide polymorphism (SNP) markers are widely used in the study of genetic diversity and genomics. Results: We report the first successful application of genotyping-by-sequencing (GBS) technology in melon. We detected 25,422 SNPs by the analysis of 72 accessions collected in Apulia, a secondary centre of diversity in Southern Italy. Analyses of genetic structure, principal components, and hierarchical clustering support the identification of three distinct subpopulations. One of them includes accessions known with the folk name of 'carosello', referable to the chate taxonomic group. This is one of the oldest domesticated forms of C. melo, once widespread in Europe and now exposed to the risk of genetic erosion. The second subpopulation contains landraces of 'barattiere', a regional vegetable production that was never characterized at the DNA level and we show was erroneously considered another form of chate melon. The third subpopulation includes genotypes of winter melon (C. melo var. inodorus). Genetic analysis within each subpopulation revealed patterns of diversity associated with fruit phenotype and geographical origin. We used SNP data to describe, for each subpopulation, the average linkage disequilibrium (LD) decay, and to highlight genomic regions possibly resulting from directional selection and associated with phenotypic variation. Conclusions: We used GBS to characterize patterns of genetic diversity and genomic features within C. melo. We provide useful information to preserve endangered gene pools and to guide the use of germplasm in breeding. Finally, our findings lay a foundation for molecular breeding approaches and the identification of genes underlying phenotypic traits
Elliptic operators on manifolds with singularities and K-homology
It is well known that elliptic operators on a smooth compact manifold are
classified by K-homology. We prove that a similar classification is also valid
for manifolds with simplest singularities: isolated conical points and fibered
boundary. The main ingredients of the proof of these results are: an analog of
the Atiyah-Singer difference construction in the noncommutative case and an
analog of Poincare isomorphism in K-theory for our singular manifolds.
As applications we give a formula in topological terms for the obstruction to
Fredholm problems on manifolds with singularities and a formula for K-groups of
algebras of pseudodifferential operators.Comment: revised version; 25 pages; section with applications expande
Adsorption of Rhodamine B from Wastewater on the Arsenic- Hyperaccumulator Pteris Vittata Waste Roots
The Pteris vittata fern, which is a perennial plant known for hyper-accumulating Arsenic, can be grown in hydroponic cultures and is often used for phytoremediation of contaminated water. To reduce the cost of disposing As-contaminated biomass, this study examined the potential of using waste roots from Pteris vittata as a new and inexpensive bio-adsorbent for removing Rhodamine B (RB) dye, which is commonly used in industrial applications. Batch tests were performed at 25°C in order to observe both the rate and the equilibrium conditions of the system. The isotherm showed a typical Langmuir behavior exhibiting a maximum adsorption capacity of 42.7 mg/g. Kinetics tests were conducted at different solid-liquid ratios and fitted by a mathematical model. The maximum likelihood method was employed to estimate the effective diffusivity of RB in the solid which resulted 4.48 10-9 cm2/min. This study lays the groundwork for future investigations into the use of this material in continuous systems to determine its feasibility for application in industrial apparatus
Use of drugs for attrv amyloidosis in the real world: How therapy is changing survival in a non-endemic area
Background: Over the past decade, three new drugs have been approved for the treatment of hereditary amyloid transthyretin (ATTRv) polyneuropathy. The aim of this work was to analyze whether current therapies prolong survival for patients affected by ATTRv amyloidosis. Methods: The study was conducted retrospectively, analyzing the medical records of 105 patients with genetic diagnoses of familial amyloidotic polyneuropathy followed at the two referral centers for the disease in Sicily, Italy. Of these, 71 received disease-modifying therapy, while 34 received only symptomatic treatment or no therapy. Results: The most used treatment in our patient cohort was tafamidis, followed by liver transplantation, patisiran, inotersen, and diflunisal. The median survival was significantly longer for treated vs. untreated patients (12 years vs. 8 years). In the 71 patients who received disease-modifying treatment, the presence of cardiac involvement, weight loss, or autonomic dysfunction at diagnosis was not related to survival. Conversely, patients diagnosed in the early stage of the disease (PND 1) had significantly longer survival than those diagnosed in the late stage (PND 2–4)
The critical Ising lines of the d=2 Ashkin-Teller model
The universal critical point ratio is exploited to determine positions of
the critical Ising transition lines on the phase diagram of the Ashkin-Teller
(AT) model on the square lattice. A leading-order expansion of the ratio in
the presence of a non-vanishing thermal field is found from finite-size scaling
and the corresponding expression is fitted to the accurate perturbative
transfer-matrix data calculations for the square clusters with
.Comment: RevTex, 4 pages, two figure
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