2 research outputs found
Bone mineral density, bone remodeling and osteoprotegerin in patients with acute coronary syndrome
Producción CientíficaThe objective of this study was to evaluate the relationship between coronary disease and osteoporosis and determine the effect of
osteoprotegerin (OPG) on bone remodeling and bone mineral density (BMD) in a group of patients with acute coronary syndrome. Eightythree
patients (52 males and 31 women) with acute coronary syndrome (75 patients with acute myocardial infarction and 8 with unstable
angina) with an average age of 61±10 years were studied. Levels of osteocalcin, urinarydeoxypyridinoline, OPG and the receptor activator of
nuclear factor-κB ligand (RANKL) were determined during the hospital stay. Femoral neck, trochanter and lumbar spine densitometry was
carried out using a DXA densitometer. Thirty percent of patients presented osteoporosis (39% of females and 26% of males). Osteoporotic
patients were older and had a lower weight and height and elevated serum levels of osteocalcin (3.6±2.25 2.63 versus ±1.55, p=0.05).
Levels of OPG and RANKL were similar in both groups and showed no relationship with BMD. In conclusion, no relationship was observed
between the OPG/RANKL system and BMD in these patients
Valor pronóstico de los anticuerpos anti-Chlamydia pneumoniae en la cardiopatía isquémica
Producción CientíficaSe ha relacionado la
enfermedad arterial coronaria con infección por
Chlamydia pneumoniae, pero existen pocos estudios
que valoren la presencia de anticuerpos frente a este
microorganismo y el pronóstico de los pacientes con
cardiopatía isquémica. El objetivo de nuestro estudio
fue valorar el impacto de la positividad de
anticuerpos anti-Chlamydia pneumoniae en la
morbimortalidad asociada a la cardiopatía isquémica