Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

Prediction Of The In Planta Phakopsora Pachyrhizi Secretome And Potential Effector Families

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Asian soybean rust (ASR), caused by the obligate biotrophic fungus Phakopsora pachyrhizi, can cause losses greater than 80%. Despite its economic importance, there is no soybean cultivar with durable ASR resistance. In addition, the P. pachyrhizi genome is not yet available. However, the availability of other rust genomes, as well as the development of sample enrichment strategies and bioinformatics tools, has improved our knowledge of the ASR secretome and its potential effectors. In this context, we used a combination of laser capture microdissection (LCM), RNAseq and a bioinformatics pipeline to identify a total of 36 350 P. pachyrhizi contigs expressed in planta and a predicted secretome of 851 proteins. Some of the predicted secreted proteins had characteristics of candidate effectors: small size, cysteine rich, do not contain PFAM domains (except those associated with pathogenicity) and strongly expressed in planta. A comparative analysis of the predicted secreted proteins present in Pucciniales species identified new members of soybean rust and new Pucciniales- or P. pachyrhizi-specific families (tribes). Members of some families were strongly up-regulated during early infection, starting with initial infection through haustorium formation. Effector candidates selected from two of these families were able to suppress immunity in transient assays, and were localized in the plant cytoplasm and nuclei. These experiments support our bioinformatics predictions and show that these families contain members that have functions consistent with P. pachyrhizi effectors.183363377Coordenacao de aperfeicoamento de pessoal de nivel superior (CAPES)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) (Genosoja Project)Empresa Brasileira de Pesquisa Agropecuaria (Embrapa) (Government of Brazil)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms

ABSTRACTLong-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affects the host gut microbiota, which is linked to disease severity in patients with COVID-19. Here, we report that the gut microbiota of post-COVID subjects had a remarkable predominance of Enterobacteriaceae strains with an antibiotic-resistant phenotype compared to healthy controls. Additionally, short-chain fatty acid (SCFA) levels were reduced in feces. Fecal transplantation from post-COVID subjects to germ-free mice led to lung inflammation and worse outcomes during pulmonary infection by multidrug-resistant Klebsiella pneumoniae. transplanted mice also exhibited poor cognitive performance. Overall, we show prolonged impacts of SARS-CoV-2 infection on the gut microbiota that persist after subjects have cleared the virus. Together, these data demonstrate that the gut microbiota can directly contribute to post-COVID sequelae, suggesting that it may be a potential therapeutic target

Evidências de validade entre a Escala de Depressão (EDEP), o BDI e o Inventário de Percepção de Suporte Familiar (IPSF) Validity evidences between the Depression Scale (EDEP), the BDI and the Perception of Family Support Inventory (IPSF)

A depressão é contemporaneamente definida como um transtorno de humor, marcada por um conjunto de sinais, sintomas, comportamentos e manisfestações fisiológicas apresentadas pelos indivíduos acometidos. Dentre os fatores relacionados com o desenvolvimento e manutenção da depressão, encontra-se o suporte familiar, entendido como manifestação de atenção, carinho, diálogo, liberdade, proximidade afetiva, autonomia e independência existente entre os integrantes da família. A presente pesquisa teve como objetivos a busca por evidências de validade para a Escala de Depressão (EDEP) baseada na relação com outras variáveis, avaliando o mesmo construto, ou seja, depressão sendo mensurada também pelo Inventário de Depressão de Beck - BDI e, ainda, avaliando construtos relacionados, sendo o suporte familiar mensurado pelo Inventário de Percepção de Suporte Familiar - IPSF. Participaram desta pesquisa 157 estudantes de uma universidade particular do sul de Minas Gerais, 75,5% do sexo feminino e 24,5% do sexo masculino, com idade média de 23,22 anos (DP=6,4), variando entre 18 e 51 anos. Nos resultados, encontraram-se correlações altas, positivas e significativas entre EDEP e BDI, conforme esperado, indicando que quanto maior a pontuação nas escalas, maior sintomatologia depressiva. Nas correlações entre a EDEP e as dimensões do IPSF, foram encontradas correlações negativas e significativas, sugerindo que quanto maior a sintomatologia de depressão, pior a percepção do suporte familiar recebido. Foram encontradas apenas diferenças marginalmente significativas entre os sexos, no que diz respeito à sintomatologia depressiva (EDEP e BDI), indicando que mulheres pontuariam mais nas escalas de depressão.<br>Depression is contemporary defined as a mood disorder, shown by a set of individual's signs, symptoms, behaviors and physiological manifestations. Among the related factors to developing and maintaining depression, there's family support, understood as manifestation of attention, care, dialog, freedom, affective proximity, autonomy and independence between family members. The present research aimed to search for validity evidences to Depression Scale (EDEP) based on the relation to other variables assessing the same construct, depression, being also assessed by Beck Depression Inventory - BDI, and assessing related constructs, family support, measured by Perception of Family Support Inventory - IPSF. 157 undergraduates from a private university located in south state of Minas Gerais, 75,5% from female gender and 24,5% from male gender, aging from 18 to 51 years old (M=23,2; DP=6,4) took part in this study. At the results, high, significant and positive correlations were found between EDEP and BDI, as expected, indicating that the higher the scores on both scales, higher the depressive symptoms. As for the correlations between EDEP and IPSF dimensions, significant and negative correlations were found, suggesting that the higher depressive symptoms lower the perception of family support on individuals. Only marginally significant differences were found between genders, as to depressive symptoms (EDEP and BDI), indicating that women would score more at the depression scales

Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

Abstract The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, and dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus across the country since its first detection in 2014 in Northeast Brazil. In this work, we carried out on-site training activities in genomic surveillance in partnership with the National Network of Public Health Laboratories that have led to the generation of 422 chikungunya virus genomes from 12 Brazilian states over the past two years (2021–2022), a period that has seen more than 312 thousand chikungunya fever cases reported in the country. These genomes increased the amount of available data and allowed a more comprehensive characterization of the dispersal dynamics of the chikungunya virus East-Central-South-African lineage in Brazil. Tree branching patterns revealed the emergence and expansion of two distinct subclades. Phylogeographic analysis indicated that the northeast region has been the leading hub of virus spread towards other regions. Increased frequency of C > T transitions among the new genomes suggested that host restriction factors from the immune system such as ADAR and AID/APOBEC deaminases might be driving the genetic diversity of the chikungunya virus in Brazil