Additional file 1: Table S1. of Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination

Antibodies used in the study. Each antibody used in this study is listed together with its supplier, species, type (monoclonal/polyclonal), dilution and reference. (DOCX 16 kb

Additional file 3: Figure S2. of Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination

EGFR is expressed in early oligodendrocyte precursors. Photomicrographs from embryonic spinal cord (ventral ventricular zone, E13) and perilesional adult corpus callosum (3dpi) WT mice tissue sections show representative confocal images of EGFR (green), Sox2 or PDGFRα (red) and DAPI (blue) immunoreactivities. Asterisks indicate PDGFRα+/EGFR− cells and arrowheads indicate PDGFRα+/EGFR+ cells (Representative images from n = 3). Scale bars: 10 μm. (TIF 585 kb

Additional file 4: Figure S3. of Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination

tPA is not detected in PDFGR-β + pericytes. (A) Photomicrographs from adult WT mice tissue sections show representative confocal images of PDGFR-β (green), tPA (red) and DAPI (blue) immunoreactivities in the lesion 3 days after injection. (Representative images from n = 3). Inlets show side view reconstructions of the z-stack. (B) Representative fluorescent intensity/distance graph measured from confocal image in (A) showing that tPA (Red) is not found in colocalization with PDGFR-β staining. (TIF 328 kb