Additional file 3: Figure S2. of Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination
EGFR is expressed in early oligodendrocyte precursors. Photomicrographs from embryonic spinal cord (ventral ventricular zone, E13) and perilesional adult corpus callosum (3dpi) WT mice tissue sections show representative confocal images of EGFR (green), Sox2 or PDGFRα (red) and DAPI (blue) immunoreactivities. Asterisks indicate PDGFRα+/EGFR− cells and arrowheads indicate PDGFRα+/EGFR+ cells (Representative images from n = 3). Scale bars: 10 μm. (TIF 585 kb