Neutrino spin evolution in presence of general external fields

The derivation of the quasiclassical Lorentz invariant neutrino spin evolution equation taking into account general types of neutrino non-derivative interactions with external fields is presented. We discuss the constraints on the characteristics of matter and neutrino under which this quasiclassical approach is valid. The application of the obtained equation for the case of the Standard Model neutrino interactions with moving and polarized background matter is considered.Comment: The form of the article has been sufficiently improve

Spin light of neutrino in gravitational fields

We predict a new mechanism for the spin light of neutrino ($SL\nu$) that can be emitted by a neutrino moving in gravitational fields. This effect is studied on the basis of the quasiclassical equation for the neutrino spin evolution in a gravitational field. It is shown that the gravitational field of a rotating object, in the weak-field limit, can be considered as an axial vector external field which induces the neutrino spin procession. The corresponding probability of the neutrino spin oscillations in the gravitational field has been derived for the first time. The considered in this paper $SL\nu$ can be produced in the neutrino spin-flip transitions in gravitational fields. It is shown that the total power of this radiation is proportional to the neutrino gamma factor to the fourth power, and the emitted photon energy, for the case of an ultra relativistic neutrino, could span up to gamma-rays. We investigate the $SL\nu$ caused by both gravitational and electromagnetic fields, also accounting for effects of arbitrary moving and polarized matter, in various astrophysical environments. In particular, we discuss the $SL\nu$ emitted by a neutrino moving in the vicinity of a rotating neutron star, black hole surrounded by dense matter, as well as by a neutrino propagating in the relativistic jet from a quasar.Comment: 14 pages in LaTex with 1 eps figure; derivation of the neutrino spin oscillations probability in gravitational fields and several clarifying notes are added, typos correcte

Application of ultrasonic testing method for determining defects of hot-deformed powder materials

The article is devoted to the analysis of elastic and plastic characteristics of composite materials during hot stamping. The purpose of this work is to offer optimal conditions for hot plasticity of composite porous material with determination of temperature conditions of hot stamping excluding the appearance of defects in the structure. Production of details of the difficult form by method of hot stamping from preparations of the cylindrical form is followed by development of barrel on a peripheral surface. Sludge sintered porous blanks, and sediment compact material, accompanied by a nonuniform height lateral deformation. In connection with the action of friction forces on the contact surfaces, this leads to the formation of a “barrel”. The heterogeneity of the deformed state is associated with the appearance of tangential tensile stresses on the free surface of the workpiece. If they exceed some critical degree of transverse deformation, cracks appear on the side surface, which leads to gas saturation (oxidation) of the inner layers of the forging, to the ingress of grease into them and its pressing into the volume of the part during hot stamping. In the end, this significantly reduces the properties of hot-stamped parts. Conclusion: the methods of determining the elastic characteristics depending on the geometric parameters of the workpieces, the applied strain energy, body density and temperature dependence of the plasticity characteristics of the hot deformation of the powder material are сonsidered

The Novel Gallium Aminobisphenolate Initiator of the Ring-Opening Copolymerization of L-Lactide and ε-Caprolactone: A Computational Study

Density functional theory (DFT) simulations of ring-opening copolymerization of ε-caprolactone (CL) and L-lactide (LA) in presence of novel gallium complex on aminobis (phenolate) ligand are conducted. The initial steps of polymerization of CL and LA as well as the first steps of propagation which led to LGa-LA-LA-OMe, LGa-LA-CL-OMe, LGa-CL-LA-OMe, or LGa-CL-CL-OMe derivatives have been analyzed in detail. According to these data, the studied catalyst is a rare example of a catalyst in which, during copolymerization, the polymerization of CL should proceed faster than LA. Thus, we predict the formation of a mainly block copolymer poly(CL-block-LA) using this catalyst

Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis

Rheumatoid arthritis is one of the most common autoimmune diseases. Many antioxidants have been tested in arthritis, but their efficacy was, at best, marginal. In this study, a novel mitochondria-targeted antioxidant, plastoquinonyl-decyl-triphenylphosphonium bromide (SkQ1), was tested in vivo to prevent and cure experimental autoimmune arthritis. In conventional Wistar rats, SkQ1 completely prevented the development of clinical signs of arthritis if administered with food before induction. Further, SkQ1 significantly reduced the fraction of animals that developed clinical signs of arthritis and severity of pathological lesions if administration began immediately after induction of arthritis or at the onset of first symptoms (day 14 after induction). In specific pathogen-free Wistar rats, SkQ1 administered via gavage after induction of arthritis did not reduce the fraction of animals with arthritis but decreased the severity of lesions upon pathology examination in a dose-dependent manner. Efficacious doses of SkQ1 were in the range of 0.25–1.25 nmol/kg/day (0.13–0.7 μg/kg/day), which is much lower than doses commonly used for conventional antioxidants. SkQ1 promoted apoptosis of neutrophils in vitro, which may be one of the mechanisms underlying its pharmacological activity. Considering its low toxicity and the wide therapeutic window, SkQ1 may be a valuable additional therapy for rheumatoid arthritis

Purification of a recombinant membrane protein tagged with a calmodulin-binding domain: properties of chimeras of the Escherichia coli nicotinamide nucleotide transhydrogenase and the C-terminus of human plasma membrane Ca2+ -ATPase.

A Ca2+ -dependent calmodulin-binding peptide (CBP) is an attractive tag for affinity purification of recombinant proteins, especially membrane proteins, since elution is simply accomplished by removing/chelating Ca2+. To develop a single-step calmodulin/CBP-dependent purification procedure for Escherichia coli nicotinamide nucleotide transhydrogenase, a 49 amino acid large CBP or a larger 149 amino acid C-terminal fragment of human plasma membrane Ca2+ -ATPase (hPMCA) was fused C-terminally to the beta subunit of transhydrogenase. Fusion using the 49 amino acid fragment resulted in a dramatic loss of transhydrogenase expression while fusion with the 149 amino acid fragment gave a satisfactory expression. This chimeric protein was purified by affinity chromatography on calmodulin-Sepharose with mild elution with EDTA. The purity and activity were comparable to those obtained with His-tagged transhydrogenase and showed an increased stability. CBP-tagged transhydrogenase contained a 4- to 10-fold higher amount of the alpha subunit relative to the beta subunit as compared to wild-type transhydrogenase. To determine whether the latter was due to the CBP tag, a double-tagged transhydrogenase with both an N-terminal 6x His-tag and a CBP-tag, purified by using either tag, gave no significant increase in purity as compared to the single-tagged protein. The reasons for the altered subunit composition are discussed. The results suggest that, depending on the construct, the CBP-tag may be a suitable affinity purification tag for membrane proteins in general

Size Distribution of Inactivated Tick-Borne Encephalitis Virus Particles Revealed by a Comprehensive Physicochemical Approach

Tick-borne encephalitis virus (TBEV) is an enveloped RNA virus, a member of the genus Flavivirus (family Flaviviridae). Here, we provide a detailed analysis of the size and structure of the inactivated TBEV vaccine strain Sofjin-Chumakov. Four analytical methods were used to analyze individual TBEV particles—negative staining TEM, cryo-EM, atomic force microscopy (AFM), and nanoparticle tracking analysis (NTA). All methods confirmed that the particles were monodisperse and that their mean size was ~50 nm. Cryo-EM data allowed us to obtain a 3D electron density model of the virus with clearly distinguishable E protein molecules. STEM-EELS analysis detected phosphorus in the particles, which was interpreted as an indicator of RNA presence. Altogether, the described analytical procedures can be valuable for the characterization of inactivated vaccine virus samples

Defect properties of InGaAsN layers grown as sub-monolayer digital alloys by molecular beam epitaxy

International audienceThe defect properties of InGaAsN dilute nitrides grown as sub-monolayer digital alloys (SDAs) by molecular beam epitaxy for photovoltaic application were studied by space charge capacitance spectroscopy. Alloys of i-InGaAsN (Eg = 1.03 eV) were lattice-matched grown on GaAs wafers as a superlattice of InAs/GaAsN with one monolayer of InAs (<0.5 nm) between wide GaAsN (7–12 nm) layers as active layers in single-junction solar cells. Low p-type background doping was demonstrated at room temperature in samples with InGaAsN layers 900 nm and 1200 nm thick (less 1 × 1015 cm−3). According to admittance spectroscopy and deep-level transient spectroscopy measurements, the SDA approach leads to defect-free growth up to a thickness of 900 nm. An increase in thickness to 1200 nm leads to the formation of non-radiative recombination centers with an activation energy of 0.5 eV (NT = 8.4 × 1014 cm−3) and a shallow defect level at 0.20 eV. The last one leads to the appearance of additional doping, but its concentration is low (NT = 5 × 1014 cm−3) so it does not affect the photoelectric properties. However, further increase in thickness to 1600 nm, leads to significant growth of its concentration to (3–5) × 1015 cm−3, while the concentration of deep levels becomes 1.3 × 1015 cm−3. Therefore, additional free charge carriers appearing due to ionization of the shallow level change the band diagram from p-i-n to p-n junction at room temperature. It leads to a drop of the external quantum efficiency due to the effect of pulling electric field decrease in the p-n junction and an increased number of non-radiative recombination centers that negatively impact lifetimes in InGaAsN