BOOMERanG Constraints on Primordial Non-Gaussianity from Analytical Minkowski Functionals

We use Minkowski Functionals (MF) to constrain a primordial non-Gaussian contribu- tion to the CMB intensity field as observed in the 150 GHz and 145 GHz BOOMERanG maps from the 1998 and 2003 flights, respectively, performing for the first time a joint analysis of the two datasets. A perturbative expansion of the MF formulae in the limit of a weakly non-Gaussian field yields analytical formulae, derived by Hikage et al. (2006), which can be used to constrain the coupling parameter fNL without the need for non-Gaussian simulations. We find -1020 < fNL < 390 at 95% CL, significantly improving the previous constraints by De Troia et al. (2007) on the BOOMERanG 2003 dataset. These are the best fNL limits to date for suborbital probes

Italian guidelines for primary headaches: 2012 revised version

The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in adults was published in J Headache Pain 2(Suppl. 1):105–190 (2001). Ten years later, the guideline committee of the Italian Society for the Study of Headaches (SISC) decided it was time to update therapeutic guidelines. A literature search was carried out on Medline database, and all articles on primary headache treatments in English, German, French and Italian published from February 2001 to December 2011 were taken into account. Only randomized controlled trials (RCT) and meta-analyses were analysed for each drug. If RCT were lacking, open studies and case series were also examined. According to the previous edition, four levels of recommendation were defined on the basis of levels of evidence, scientific strength of evidence and clinical effectiveness. Recommendations for symptomatic and prophylactic treatment of migraine and cluster headache were therefore revised with respect to previous 2001 guidelines and a section was dedicated to non-pharmacological treatment. This article reports a summary of the revised version published in extenso in an Italian version