Calcium, Orai1, and Epidermal Proliferation

Ca2+ influx controls essential epidermal functions, including proliferation, differentiation, cell migration, itch, and barrier homeostasis. The Orai1 ion channel allows capacitive Ca2+ influx after Ca2+ release from the endoplasmic reticulum, and it has now been shown to modulate epidermal atrophy. These findings reveal new interactions among various Ca2+ signaling pathways and uncover novel functions for Ca2+ signaling via the Orai1 channel

Bone marrow-derived mesenchymal cell differentiation toward myogenic lineages: Facts and perspectives

Bone marrow-derived mesenchymal stem cells (BM-MSCs) are valuable platforms for new therapies based on regenerative medicine. BM-MSCs era is coming of age since the potential of these cells is increasingly demonstrated. In fact, these cells give origin to osteoblasts, chondroblasts, and adipocyte precursors in vitro, and they can also differentiate versus other mesodermal cell types like skeletal muscle precursors and cardiomyocytes. In our short review, we focus on the more recent manipulations of BM-MSCs toward skeletal and heart muscle differentiation, a growing field of obvious relevance considering the toll of muscle disease (i.e., muscular dystrophies), the heavier toll of heart disease in developed countries, and the still not completely understood mechanisms of muscle differentiation and repair

Passing quantum correlations to qubits using any two-mode state

We draw an explicit connection between the statistical properties of an entangled two-mode continuous variable (CV) resource and the amount of entanglement that can be dynamically transferred to a pair of non-interacting two-level systems. More specifically, we rigorously reformulate entanglement transfer process by making use of covariance matrix formalism. When the resource state is Gaussian, our method makes the approach to the transfer of quantum correlations much more flexible than in previously considered schemes and allows the straightforward inclusion of the effects of noise affecting the CV system. Moreover, the proposed method reveals that the use of de-Gaussified two-mode states is almost never advantageous for transferring entanglement with respect to the full Gaussian picture, despite the entanglement in the non-Gaussian resource can be much larger than in its Gaussian counterpart. We can thus conclude that the entanglement-transfer map overthrows the "ordering" relations valid at the level of CV resource states.Comment: 10 pages, 6 figures, RevTeX4, Accepted for publication in Physical Review

Eco-friendly gas mixtures for Resistive Plate Chambers based on Tetrafluoropropene and Helium

Due to the recent restrictions deriving from the application of the Kyoto protocol, the main components of the gas mixtures presently used in the Resistive Plate Chambers systems of the LHC experiments will be most probably phased out of production in the coming years. Identifying possible replacements with the adequate characteristics requires an intense R&D, which was recently started, also in collaborations across the various experiments. Possible candidates have been proposed and are thoroughly investigated. Some tests on one of the most promising candidate - HFO-1234ze, an allotropic form of tetrafluoropropane- have already been reported. Here an innovative approach, based on the use of Helium, to solve the problems related to the too elevate operating voltage of HFO-1234ze based gas mixtures, is discussed and the relative first results are shown.Comment: 9 pages, 6 figures, 1 tabl

YF-12 cooperative airframe/propulsion control system program, volume 1

Several YF-12C airplane analog control systems were converted to a digital system. Included were the air data computer, autopilot, inlet control system, and autothrottle systems. This conversion was performed to allow assessment of digital technology applications to supersonic cruise aircraft. The digital system was composed of a digital computer and specialized interface unit. A large scale mathematical simulation of the airplane was used for integration testing and software checkout

Transferring entanglement to the steady-state of flying qubits

The transfer of entanglement from optical fields to qubits provides a viable approach to entangling remote qubits in a quantum network. In cavity quantum electrodynamics, the scheme relies on the interaction between a photonic resource and two stationary intracavity atomic qubits. However, it might be hard in practice to trap two atoms simultaneously and synchronize their coupling to the cavities. To address this point, we propose and study entanglement transfer from cavities driven by an entangled external field to controlled flying qubits. We consider two exemplary non-Gaussian driving fields: NOON and entangled coherent states. We show that in the limit of long coherence time of the cavity fields, when the dynamics is approximately unitary, entanglement is transferred from the driving field to two atomic qubits that cross the cavities. On the other hand, a dissipation-dominated dynamics leads to very weakly quantum-correlated atomic systems, as witnessed by vanishing quantum discord.Comment: 8 pages, 4 figures, RevTeX

Operational distance and fidelity for quantum channels

We define and study a fidelity criterion for quantum channels, which we term the minimax fidelity, through a noncommutative generalization of maximal Hellinger distance between two positive kernels in classical probability theory. Like other known fidelities for quantum channels, the minimax fidelity is well-defined for channels between finite-dimensional algebras, but it also applies to a certain class of channels between infinite-dimensional algebras (explicitly, those channels that possess an operator-valued Radon--Nikodym density with respect to the trace in the sense of Belavkin--Staszewski) and induces a metric on the set of quantum channels which is topologically equivalent to the CB-norm distance between channels, precisely in the same way as the Bures metric on the density operators associated with statistical states of quantum-mechanical systems, derived from the well-known fidelity (`generalized transition probability') of Uhlmann, is topologically equivalent to the trace-norm distance.Comment: 26 pages, amsart.cls; improved intro, fixed typos, added a reference; accepted by J. Math. Phy

Two proposals for testing quantum contextuality of continuous-variable states

We investigate the violation of non-contextuality by a class of continuous variable states, including variations of entangled coherent states (ECS's) and a two-mode continuous superposition of coherent states. We generalise the Kochen-Specker (KS) inequality discussed in A. Cabello, Phys. Rev. Lett. {\bf 101}, 210401 (2008) by using effective bidimensional observables implemented through physical operations acting on continuous variable states, in a way similar to an approach to the falsification of Bell-CHSH inequalities put forward recently. We test for state-independent violation of KS inequalities under variable degrees of state entanglement and mixedness. We then demonstrate theoretically the violation of a KS inequality for any two-mode state by using pseudo-spin observables and a generalized quasi-probability function.Comment: 7 pages, 2 figures, RevTeX