1,291 research outputs found

    Multi-objective optimization of building energy design to reconcile collective and private perspectives: CO2-eq vs. Discounted payback time

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    Building energy design is a multi-objective optimization problem where collective and private perspectives conflict each other. For instance, whereas the collectivity pursues the minimization of environmental impact, the private pursues the maximization of financial viability. Solving such trade-off design problems usually involves a big computational cost for exploring a huge solution domain including a large number of design options. To reduce that computational cost, a bi-objective simulation-based optimization algorithm, developed in a previous study, is applied in the present investigation. The algorithm is implemented for minimizing the CO2-eq emissions and the discounted payback time (DPB) of a single-family house in cold climate, where 13,456 design solutions including building envelope and heating system options are explored and compared to a predefined reference case. The whole building life is considered by assuming a calculation period of 30 years. The results show that the type of heating system significantly affects energy performance; notably, the ground source heat pump leads to the highest reduction in CO2-eq emissions, around 1300 kgCO2-eq/m2, with 17 year DPB; the oil fire boiler can provide the lowest DPB, equal to 8.5 years, with 850 kgCO2-eq/m2 reduction. In addition, it is shown that using too high levels of thermal insulation is not an effective solution as it causes unacceptable levels of summertime overheating. Finally a multi-objective decision making approach is proposed in order to enable the stakeholders to choice among the optimal solutions according to the weight given to each objective, and thus to each perspectiv

    Predicting the Impact of Climate Change on Thermal Comfort in A Building Category: The Case of Linear-type Social Housing Stock in Southern Spain

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    The Climate Change scenario projected by the IPCC for the year 2050 predicts noticeable increases in temperature. In severe summer climates, such as the Mediterranean area, this would have very negative e ects on thermal comfort in the existing housing stock, given the current high percentage of dwellings which are obsolete in energy terms and house a population at serious risk of energy poverty. The main aim of this paper is to generate a predictive model in order to assess the impact of this future climate scenario on thermal comfort conditions in an entire building category. To do so, calibrated models representing linear-type social multi-family buildings, dating from the post-war period and located in southern Spain, will be simulated extensively using transient energy analyses performed by EnergyPlus. In addition, a sensitivity analysis will be performed to identify the most influential parameters on thermal discomfort. The main results predict a generalized deterioration in indoor thermal comfort conditions due to global warming, increasing the average percentage of discomfort hours during the summer by more than 35%. This characterization of the future thermal behaviour of the residential stock in southern Spain could be a trustworthy tool for decision-making in energy retrofitting projects which are so badly needed. To do so, further work is required on some limitations of this model so that di erent user profiles and typologies can be represented in detail and an economic assessment can be included

    villas on islands cost effective energy refurbishment in mediterranean coastline houses

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    Abstract This paper aims to underline the variability of constructions in Mediterranean regions, where different climates, architectural techniques and kinds of building uses determine different optimal energy refurbishments of residential buildings placed on the coastline. More in detail, by considering two different construction technologies (i.e., a lightweight house in reinforced concrete and a massive tuff-made villa), two different climates (Greek coast, climate of Athens and Italian coast, climate of Naples), two cost-optimal energy retrofits are presented. The optimized energy retrofit, performed by coupling transient energy simulations and genetic algorithm for generating improved models, have taken into account all levers of energy efficiency, and thus optimization of building envelope (thermal insulation, reflectance, windows and solar screens), active energy systems (daylight control, HVAC systems for the regulation of indoor conditions) and renewable energy sources at the building scale (namely, solar photovoltaic)

    Thermal Dynamic Insulation: Numerical Modeling in a Transient Regime and Application to Alternative Aviary Houses

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    Abstract The paper proposes a numerical model for investigating the energy performance of thermal dynamic insulation in transient conditions. This technology consists of porous building components that are permeable to airflow, ensuring high levels of energy performance and IAQ. The model is implemented in MATLAB environment and allows an accurate evaluation of heat transfer through porous media, with the final purpose of quantifying the energy benefits deriving from dynamic insulation. Beyond its presentation, the model is used to investigate the implementation of a dynamically-insulated ceiling to an alternative aviary house for laying-hens, located in Des Moines, Iowa (U.S.). The proposed system produces thermal, energy and economical savings in both cold and warm seasons

    Is indoor overheating an upcoming risk in southern Spain social housing stocks? Predictive assessment under a climate change scenario

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    Beyond thermal comfort, the future outlook of climate change poses a challenge for the health of the most vulnerable inhabitants of the existing residential stock. In southern Spain specifically there is extensive social housing stock that is obsolete from an energy perspective and occupied by an aging population with economic constraints for the use of energy. The main aim of this work is to evaluate the possible comfort risks in terms of overheating following the different criteria established by the Chartered Institution of Building Services Engineers (CIBSE), both under current conditions and in a climate change scenario. For this purpose, a parametric simulation model was developed to reliably evaluate the category of linear-type social housing from the postwar period, a total of more than 42,000 dwellings. The results show that around 38% of the evaluated cases are already at risk of overheating as they fail to meet two of the three adaptive criteria set in TM52. By 2050 this figure will be almost 100%. In addition, it is expected that global warming will result in an increase of up to 40% in the percentage of Hours of Exceedance

    Anthracyclines gels: Chemical structure and functional behaviour

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    Anthracyclines are a family of antibiotics often used in cancer chemotherapy. Daunorubicin (DA) was the first isolated from a strain of Streptomyces peucetius back in 1960 and still in use for the treatment of several malignancies together with the even more frequently used analogue Doxorubicin (DX, also called Adriamycin) and its semisynthetic derivative Epirubicyn (EPI). Despite their extremely close chemical formula (Figure 1), their properties when in solution are enormously different. In fact, whereas the increase of the ionic strength induces the formation of a gel with DX1-3, in the case of the related EPI and DA molecules what is observed are only the well-known self-association phenomena documented in the literature from decades4. Please click Additional Files below to see the full abstract

    Energy Analysis of a Real Industrial Building: Model Development, Calibration via Genetic Algorithm and Monitored Data, Optimization of Photovoltaic Integration

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    This study performs the energy analysis of a real industrial building, located near Naples (South Italy). The used approach includes three phases: development of the energy model, model calibration based on monitored data and optimization of photovoltaic (PV) integration. Monitored data provide the monthly overall electricity demands of the facility for different years, while the load factors of industrial devices are not available. Thus, the assessment of hourly and daily trends of electricity demands and internal heat loads is not possible from monitored data. In order to solve such issue, the energy model of the building is developed under EnergyPlus environment, taking account of the existing PV system too. A genetic algorithm is run by coupling EnergyPlus and MATLAB® to properly calibrate the hourly load factors of the devices in order to achieve a good agreement between simulated and monitored values of monthly electricity demands. Finally, the installation of further PV panels is investigated to optimize the photovoltaic integration with a view to cost-effectiveness. The robustness of the optimization process is ensured using the calibrated energy model, which provides reliable hourly values of building electricity demand. Results show that the electricity produced by the additional PV panels is around 160 MWh per year, while the payback period is around 10 years demonstrating the financial viability of PV integration

    Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury

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    The liver is susceptible to such oxidative and metabolic stresses as ischemia-reperfusion (I/R) and fatty acid accumulation. Probiotics are viable microorganisms that restore the gut microbiota and exert a beneficial effect on the liver by inhibiting bacterial enzymes, stimulating immunity, and protecting intestinal permeability. We evaluated Lactobacillus paracasei F19 (LP-F19), for its potential protective effect, in an experimental model of I/R (30 min ischemia and 60 min reperfusion) in rats fed a standard diet or a steatogen [methionine/choline-deficient (MCD)] diet. Both groups consisted of 7 sham-operated rats, 10 rats that underwent I/R, and 10 that underwent I/R plus 8 wk of probiotic dietary supplementation. In rats fed a standard diet, I/R induced a decrease in sinusoid perfusion (P < 0.001), severe liver inflammation, and necrosis besides an increase of tissue levels of malondialdehyde (P < 0.001), tumor necrosis factor-alpha (P < 0.001), interleukin (IL)-1beta (P < 0.001), and IL-6 (P < 0.001) and of serum levels of transaminase (P < 0.001) and lipopolysaccharides (P < 0.001) vs. sham-operated rats. I/R also induced a decrease in Bacterioides, Bifidobacterium, and Lactobacillus spps (P < 0.01, P < 0.001, and P < 0.001, respectively) and an increase in Enterococcus and Enterobacteriaceae (P < 0.01 and P < 0.001, respectively) on intestinal mucosa. The severity of liver and gut microbiota alterations induced by I/R was even greater in rats with liver inflammation and steatosis, i.e., MCD-fed animals. LP-F19 supplementation significantly reduced the harmful effects of I/R on the liver and on gut microbiota in both groups of rats, although the effect was slightly less in MCD-fed animals. In conclusion, LP-F19 supplementation, by restoring gut microbiota, attenuated I/R-related liver injury, particularly in the absence of steatosis

    Estimation of Insulin Resistance in Mexican Adults by the [ 13

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    Objective. To evaluate the efficacy of the [13C]glucose breath test for measuring insulin resistance in Mexican adults with different glycemic states. Research Design and Methods. Fifty-eight adults underwent a [13C]glucose breath test with simultaneous measurement of total CO2 production by indirect calorimetry, at baseline and 90 minutes after the ingestion of 15 g of dextrose and 25 mg of [13C]glucose. HOMA was used as a marker of insulin resistance. Results. We found an inverse correlation between HOMA and the breath test δ13CO2 (‰), r=-0.41 (P=0.001). After adjusting for total CO2 production, correlations between HOMA and fasting glucose were less strong but remained significant. An ROC curve was constructed using δ13CO2 (‰) and HOMA values; the cut-off point was 9.99‰ δ13CO2, corresponding to a sensitivity of 80.0 (95% CI: 51.9, 95.7) and a specificity of 67.4 (95% CI: 51.5, 80.9). Conclusions. The [13C]glucose breath test is a simple noninvasive procedure but was not sufficiently robust for an accurate diagnosis of insulin resistance. Our findings suggest that the test might be helpful in identifying individuals who are not IR, which in turn may contribute to improved diabetes prevention
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