181 research outputs found
Endoscopic Tomography and Quantum-Non-Demolition
We propose to measure the quantum state of a single mode of the radiation
field in a cavity---the signal field---by coupling it via a
quantum-non-demolition Hamiltonian to a meter field in a highly squeezed state.
We show that quantum state tomography on the meter field using balanced
homodyne detection provides full information about the signal state. We discuss
the influence of measurement of the meter on the signal field.Comment: RevTeX, 10 pages, 1 eps figure with psfig. To appear In Physical
Review A 59 (January 1999
Trapping state restoration in the randomly-driven Jaynes-Cummings model by conditional measurements
We propose a scheme which can effectively restore fixed points in the quantum
dynamics of repeated Jaynes-Cummings interactions followed by atomic state
measurements, when the interaction times fluctuate randomly. It is based on
selection of superposed atomic states whose phase correlations tend to suppress
the phase fluctuations of each separate state. One suggested realization
involves the convergence of the cavity field distribution to a single Fock
state by conditional measurements performed on two-level atoms with fluctuating
velocities after they cross the cavity. Another realization involves a trapped
ion whose internal-motional state coupling fluctuates randomly. Its motional
state is made to converge to a Fock state by conditional measurements of the
internal state of the ion.Comment: RevTeX, 5 pages, four (EPS) figures automatically included through
epsfig. Physical Review A 1998 (accepted for publication) Two references
added to Ref. [8]. No other change. Final version which will appear in
Physical Review
A FALTA QUE UMA POLÍTICA DE GESTÃO DE PESSOAS FAZ
O texto trata da minha experiência na luta pela conquista, instituição e implantação da primeira carreira do corpo técnico administrativo das Ifes
Quantum Feedback for Protection of Schroedinger-cat states
We review the use of quantum feedback for combatting the decoherence of
Schroedinger-cat-like states in electromagnetic cavities, with special emphasys
on our recent proposal of an automatic mechanism based on the injection of
appropriately prepared ``probe'' and ``feedback'' Rydberg atoms. In the latter
scheme, the information transmission from the probe to the feedback atom is
directly mediated by a second auxiliary cavity. The detection efficiency for
the probe atom is no longer a critical parameter, and the decoherence time of
the linear superposition state can be significantly increased using presently
available technology.Comment: LaTeX, 11 pages, 2 figures, uses sprocl.sty. Based on a talk given by
M. Fortunato at the 1998 Lecce Conference on Foundation of Quantum Mechanics,
to appear in the Conference Proceedings (World Scientific, Singapore, 2000
Comment on ``Creating Metastable Schroedinger Cat States''
After a careful analysis of the feedback model recently proposed by Slosser
and Milburn [Phys. Rev. Lett. 75, 418 (1995)], we are led to the conclusion
that---under realistic conditions---their scheme is not significantly more
effective in the production of linear superpositions of macroscopically
distinguishable quantum states than the usual quantum-optical Kerr effect.Comment: 1 page, RevTeX, 1 eps figure (fig_1.eps), accepted for publication in
Physical Review Letters [Phys. Rev. Lett. 77 (9) (1996)
COVID-19 Is a Multifaceted Challenging Pandemic Which Needs Urgent Public Health Interventions
Until less than two decades ago, all known human coronaviruses (CoV) caused diseases so mild that they did not stimulate further advanced CoV research. In 2002 and following years, the scenario changed dramatically with the advent of the new more pathogenic CoVs, including Severe Acute Respiratory Syndome (SARS-CoV-1), Middle Eastern respiratory syndrome (MERS)-CoV, and the new zoonotic SARS-CoV-2, likely originated from bat species and responsible for the present coronavirus disease (COVID-19), which to date has caused 15,581,007 confirmed cases and 635,173 deaths in 208 countries, including Italy. SARS-CoV-2 transmission is mainly airborne via droplets generated by symptomatic patients, and possibly asymptomatic individuals during incubation of the disease, although for the latter, there are no certain data yet. However, research on asymptomatic viral infection is currently ongoing worldwide to elucidate the real prevalence and mortality of the
disease. From a clinical point of view, COVID-19 would be defined as “COVID Planet “ because it presents as a multifaceted disease, due to the large number of organs and tissues infected by the virus. Overall, based on the available published data, 80.9% of patients infected by SARS-CoV-2 develop a mild disease/infection, 13.8% severe pneumonia, 4.7% respiratory failure, septic shock, or multi-organ failure, and 3% of these cases are fatal, but mortality parameter is highly variable in dfferent countries. Clinically, SARS-CoV-2 causes severe primary interstitial viral pneumonia and a “cytokine storm syndrome”, characterized by a severe and fatal uncontrolled systemic inflammatory response triggered by the activation of interleukin 6 (IL-6) with development of endothelitis and generalized thrombosis that can lead to organ failure and death. Risk factors include advanced age and comorbidities including hypertension, diabetes, and cardiovascular disease. Virus entry occurs
via binding the angiotensin-converting enzyme 2 (ACE2) receptor present in almost all tissues and organs through the Spike (S) protein. Currently, SARS-CoV-2 infection is prevented by the use of masks, social distancing, and improved hand hygiene measures. This review summarizes the current knowledge on the main biological and clinical features of the SARS-CoV-2 pandemic, also focusing on the principal measures taken in some Italian regions to face
Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells.
Background Patients with chronic lymphocytic leukemia whose cells express CD38 and ZAP-70 and utilize unmutated Ig VH region genes have a very poor prognosis. We studied whether cells expressing CD38 and ZAP-70 are more susceptible to stimulation through B-cell receptors than are cells that do not express CD38 and ZAP-70.Design and Methods CD38-positive and CD38-negative leukemic cells were separated from single cases and compared for their response to B-cell receptor cross-linking and ZAP-70 expression. Cohort studies were also carried out by measuring the apoptotic response to surface immunoglobulin M (IgM) cross-linking in 82 patients with chronic lymphocytic leukemia and the protein tyrosine phosphorylation induced by surface IgM in 21 patients.Results CD38-positive cells, isolated from cases of chronic lymphocytic leukemia classified as CD38-positive or CD38-negative, expressed more ZAP-70 than the corresponding CD38-negative cells, exhibited more robust protein tyrosine phosphorylation and had a greater tendency to apoptosis upon B-cell receptor cross-linking. In the cohort studies, surface IgM-induced protein tyrosine phosphorylation correlated significantly with CD38 and ZAP-70 expression and with the absence of Ig VH gene mutations. Apoptosis induced by surface IgM cross-linking correlated significantly only with the proportion of CD38-positive cells. Difficulties in finding more definitive correlations were probably related to imprecision in the in vitro test system and in the definition of cases as positive or negative.Conclusions Collectively, these data indicate that CD38-positive, ZAP-70-positive cells have a greater capacity for signaling through the B-cell receptor and suggest a function for B-cell receptor signaling in promoting chronic lymphocytic leukemia cell expansion, especially within the CD38-positive fraction of the leukemic clone
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